url: =Journal of Biomedical Research (12)\nShen, Hongbing (123)\nHu, Zhibin (89)\nJin, Guangfu (42)\nDai, Juncheng (38)\nLin, Dongxin (21)\nChen, Feng (20)\nWu, Chen (19)\nWu, Tangchun (19)\nJiang, Yue (15)\nLiu, Yao (15)\nChen, Jiaping (14)\nChu, Minjie (12)\nZhu, Meng (12)\nDong, Jing (11)\nTan, Wen (10)\nWang, Jianming (10)\nZhang, Ruyang (9)\nGuo, Huan (8)\nWang, Xinru (8)\nWen, Juan (8)\nZhai, Xiangjun (8)\nCao, Songyu (7)\nChang, Jiang (7)\nChen, Yijiang (7)\nDu, Jiangbo (7)\n1. The known genetic loci for telomere length may be involved in the modification of telomeres length after birth Weng, Qiao | Du, Jiangbo | Yu, Fei | Huang, Tongtong | Chen, Mengxi | Lv, Hong | Ma, Hongxia | Hu, Zhibin | Jin, Guangfu | Hu, Yali | Shen, Hongbing\nScientific Reports 2016;6:38729.\nTelomere length varies considerably among individuals. It is highly heritable and decreases with ageing or ageing related diseases. Recently, genome-wide association studies (GWAS) have identified several genetic loci associated with telomere length in adults. However, it is unclear whether these loci represent the genetic basis of telomere length or determine the individual susceptibility to shortening during growth process. Using DNA extracted from peripheral and cord blood of 444 mother-newborn pairs from a Chinese population, we measured relative telomere length (RTL) and genotyped eight known telomere length related variants that were initially identified in populations of European descent. We observed the T allele of rs10936599 and the T allele of rs2736100 were norminally associated with shorter RTL (P = 0.041 and 0.046, respectively) in maternal samples. Furthermore, the Weighted genetic score (WGS) of eight variants was significantly associated with RTL in maternal samples (R2 = 0.012, P = 0.025). However, we didn’t detect any significant associations for any individual variant or the combined WGS with RTL in newborns. These findings didn’t support the hypothesis that telomere length related loci may affect telomere length at birth, and we suggested that these loci may play a role in telomere length modification during life course.\n4. Association of KCTD10, MVK, and MMAB polymorphisms with dyslipidemia and coronary heart disease in Han Chinese population Sun, Jie | Qian, Yun | Jiang, Yue | Chen, Jiaping | Dai, Juncheng | Jin, Guangfu | Wang, Jianming | Hu, Zhibin | Liu, Sijun | Shen, Chong | Shen, Hongbing\nLipids in Health and Disease 2016;15:171.\nThe online version of this article (doi:10.1186/s12944-016-0348-7) contains supplementary material, which is available to authorized users.\nMVK; MMAB; KCTD10; HDL-C; Coronary heart disease\n5. Y chromosome haplogroups based genome-wide association study pinpoints revelation for interactions on non-obstructive azoospermia Lu, Chuncheng | Wen, Yang | Hu, Weiyue | Lu, Feng | Qin, Yufeng | Wang, Ying | Li, Shilin | Yang, Shuping | Lin, Yuan | Wang, Cheng | Jin, Li | Shen, Hongbing | Sha, Jiahao | Wang, Xinru | Hu, Zhibin | Xia, Yankai\nScientific Reports 2016;6:33363.\nThe Y chromosome has high genetic variability with low rates of parallel and back mutations, which make up the most informative haplotyping system. To examine whether Y chromosome haplogroups (Y-hgs) could modify the effects of autosomal variants on non-obstructive azoospermia (NOA), based on our previous genome-wide association study (GWAS), we conducted a genetic interaction analysis in GWAS subjects. Logistic regression analysis demonstrated a protective effect of Y-hg O3e* on NOA. Then, we explored the potential interaction between Y-hg O3e* and autosomal variants. Our results demonstrated that there was a suggestively significant interaction between Y-hg O3e* and rs11135484 on NOA (Pinter = 9.89 × 10−5). Bioinformatic analysis revealed that genes annotated by significant single nucleotide polymorphisms (SNPs) were mainly enriched in immunological pathways. This is the first study of interactions between Y-hgs and autosomal variants on a genome-wide scale, which addresses the missing heritability in spermatogenic impairment and sheds new light on the pathogenesis of male infertility.\n6. Risk assessment model for invasive breast cancer in Hong Kong women Wang, Feng | Dai, Juncheng | Li, Mengjie | Chan, Wing-cheong | Kwok, Carol Chi-hei | Leung, Siu-lan | Wu, Cherry | Li, Wentao | Yu, Wai-cho | Tsang, Koon-ho | Law, Sze-hong | Lee, Priscilla Ming-yi | Wong, Carmen Ka-man | Shen, Hongbing | Wong, Samuel Yeung-shan | Yang, Xiaohong R. | Tse, Lap Ah\n7. Association of microRNA polymorphisms with the risk of head and neck squamous cell carcinoma in a Chinese population: a case–control study Miao, Limin | Wang, Lihua | Zhu, Longbiao | Du, Jiangbo | Zhu, Xun | Niu, Yuming | Wang, Ruixia | Hu, Zhibin | Chen, Ning | Shen, Hongbing | Ma, Hongxia\nChinese Journal of Cancer 2016;35:77.\nThe results revealed that miR-605 rs2043556 [dominant model: adjusted odds ratio (OR) 0.71, 95% confidence interval (CI) 0.58–0.88; additive model: adjusted OR 0.74, 95% CI 0.62–0.89] and miR-196a2 rs11614913 (dominant model: adjusted OR 1.36, 95% CI 1.08–1.72; additive model: adjusted OR 1.28, 95% CI 1.10–1.48) were significantly associated with the risk of oral squamous cell carcinoma (OSCC). Furthermore, when these two loci were evaluated together based on the number of putative risk alleles (rs2043556 A and rs11614913 G), a significant locus-dosage effect was noted on the risk of OSCC (Ptrend < 0.001). However, no significant association was detected between the other three SNPs (miR-149 rs2292832, miR-146a rs2910164, and miR-608 rs4919510) and HNSCC risk.\nHead and neck cancer; microRNA; Polymorphism; Squamous cell carcinoma; Susceptibility\n9. Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese Li, Yuanfeng | Si, Lanlan | Zhai, Yun | Hu, Yanling | Hu, Zhibin | Bei, Jin-Xin | Xie, Bobo | Ren, Qian | Cao, Pengbo | Yang, Fei | Song, Qingfeng | Bao, Zhiyu | Zhang, Haitao | Han, Yuqing | Wang, Zhifu | Chen, Xi | Xia, Xia | Yan, Hongbo | Wang, Rui | Zhang, Ying | Gao, Chengming | Meng, Jinfeng | Tu, Xinyi | Liang, Xinqiang | Cui, Ying | Liu, Ying | Wu, Xiaopan | Li, Zhuo | Wang, Huifen | Li, Zhaoxia | Hu, Bo | He, Minghui | Gao, Zhibo | Xu, Xiaobing | Ji, Hongzan | Yu, Chaohui | Sun, Yi | Xing, Baocai | Yang, Xiaobo | Zhang, Haiying | Tan, Aihua | Wu, Chunlei | Jia, Weihua | Li, Shengping | Zeng, Yi-Xin | Shen, Hongbing | He, Fuchu | Mo, Zengnan | Zhang, Hongxing | Zhou, Gangqiao\n10. The case-only test for gene-environment interaction is not uniformly powerful: an empirical example Wu, Chen | Chang, Jiang | Ma, Baoshan | Miao, Xiaoping | Zhou, Yifeng | Liu, Yu | Li, Yun | Wu, Tangchun | Hu, Zhibin | Shen, Hongbing | Jia, Weihua | Zeng, Yixin | Lin, Dongxin | Kraft, Peter\nGenetic epidemiology 2013;37(4):402-407.\nThe case-only test has been proposed as a more powerful approach to detect gene-environment (G×E) interactions. This approach assumes that the genetic and environmental factors are independent. While it is well known that Type I error rate will increase if this assumption is violated, it is less widely appreciated that gene-environment correlation can also lead to power loss. We illustrate this phenomenon by comparing the performance of the case-only test to other approaches to detect G×E interactions in a genome-wide association study of esophageal squamous carcinoma (ESCC) in Chinese populations. Some of these approaches do not use information on the correlation between exposure and genotype (standard logistic regression), while others seek to use this information in a robust fashion to boost power without increasing Type I error (two-step, empirical Bayes and cocktail methods). G×E interactions were identified involving drinking status and two regions containing genes in the alcohol metabolism pathway, 4q23 and 12q24. Although the case-only test yielded the most significant tests of G×E interaction in the 4q23 region, the case-only test failed to identify significant interactions in the 12q24 region which were readily identified using other approaches. The low power of the case-only test in the 12q24 region is likely due to the strong inverse association between the SNPs in this region and drinking status. This example underscores the need to consider multiple approaches to detect gene-environment interactions, as different tests are more or less sensitive to different alternative hypotheses and violations of the gene-environment independence assumption.\n11. Common genetic variation in ETV6 is associated with colorectal cancer susceptibility Wang, Meilin | Gu, Dongying | Du, Mulong | Xu, Zhi | Zhang, Suzhan | Zhu, Lingjun | Lu, Jiachun | Zhang, Rui | Xing, Jinliang | Miao, Xiaoping | Chu, Haiyan | Hu, Zhibin | Yang, Lei | Tang, Cuiju | Pan, Lei | Du, Haina | Zhao, Jian | Du, Jiangbo | Tong, Na | Sun, Jielin | Shen, Hongbing | Xu, Jianfeng | Zhang, Zhengdong | Chen, Jinfei\nNature Communications 2016;7:11478.\nGenome-wide association studies have been performed to identify genetic variants that are associated with susceptibility to colorectal cancer. Here, the authors expand on these studies and identify a variant that regulates the expression of ETV6 and find that over-expression of ETV6 blocks cell proliferation in vitro.\n12. Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer Jiang, Liyan | Huang, Jiaqi | Higgs, Brandon W. | Hu, Zhibin | Xiao, Zhan | Yao, Xin | Conley, Sarah | Zhong, Haihong | Liu, Zheng | Brohawn, Philip | Shen, Dong | Wu, Song | Ge, Xiaoxiao | Jiang, Yue | Zhao, Yizhuo | Lou, Yuqing | Morehouse, Chris | Zhu, Wei | Sebastian, Yinong | Czapiga, Meggan | Oganesyan, Vaheh | Fu, Haihua | Niu, Yanjie | Zhang, Wei | Streicher, Katie | Tice, David | Zhao, Heng | Zhu, Meng | Xu, Lin | Herbst, Ronald | Su, Xinying | Gu, Yi | Li, Shyoung | Huang, Lihua | Gu, Jianren | Han, Baohui | Jallal, Bahija | Shen, Hongbing | Yao, Yihong\n13. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci He, Meian | Xu, Min | Zhang, Ben | Liang, Jun | Chen, Peng | Lee, Jong-Young | Johnson, Todd A. | Li, Huaixing | Yang, Xiaobo | Dai, Juncheng | Liang, Liming | Gui, Lixuan | Qi, Qibin | Huang, Jinyan | Li, Yanping | Adair, Linda S. | Aung, Tin | Cai, Qiuyin | Cheng, Ching-Yu | Cho, Myeong-Chan | Cho, Yoon Shin | Chu, Minjie | Cui, Bin | Gao, Yu-Tang | Go, Min Jin | Gu, Dongfeng | Gu, Weiqiong | Guo, Huan | Hao, Yongchen | Hong, Jie | Hu, Zhibin | Hu, Yanling | Huang, Jianfeng | Hwang, Joo-Yeon | Ikram, Mohammad Kamran | Jin, Guangfu | Kang, Dae-Hee | Khor, Chiea Chuen | Kim, Bong-Jo | Kim, Hung Tae | Kubo, Michiaki | Lee, Jeannette | Lee, Juyoung | Lee, Nanette R. | Li, Ruoying | Li, Jun | Liu, JianJun | Longe, Jirong | Lu, Wei | Lu, Xiangfeng | Miao, Xiaoping | Okada, Yukinori | Ong, Rick Twee-Hee | Qiu, Gaokun | Seielstad, Mark | Sim, Xueling | Song, Huaidong | Takeuchi, Fumihiko | Tanaka, Toshihiro | Taylor, Phil R. | Wang, Laiyuan | Wang, Weiqing | Wang, Yiqin | Wu, Chen | Wu, Ying | Xiang, Yong-Bing | Yamamoto, Ken | Yang, Handong | Liao, Ming | Yokota, Mitsuhiro | Young, Terri | Zhang, Xiaomin | Kato, Norihiro | Wang, Qing K. | Zheng, Wei | Hu, Frank B. | Lin, Dongxin | Shen, Hongbing | Teo, Yik Ying | Mo, Zengnan | Wong, Tien Yin | Lin, Xu | Mohlke, Karen L. | Ning, Guang | Tsunoda, Tatsuhiko | Han, Bok-Ghee | Shu, Xiao-Ou | Tai, E. Shyong | Wu, Tangchun | Qi, Lu\n14. Telomere length, genetic variants and risk of squamous cell carcinoma of the head and neck in Southeast Chinese Gu, Yayun | Yu, Chengxiao | Miao, Limin | Wang, Lihua | Xu, Chongquan | Xue, Wenjie | Du, Jiangbo | Yuan, Hua | Dai, Juncheng | Jin, Guangfu | Hu, Zhibin | Ma, Hongxia | Shen, Hongbing\nScientific Reports 2016;6:20675.\nTelomere dysfunction participates in malignant transformation and tumorigenesis. Previous studies have explored the associations between telomere length (TL) and cancer susceptibility; however, the findings are inconclusive. The associations between genetic variants and TL have been verified by quite a few genome-wide association studies (GWAS). Yet, to date, there was no published study on the relationship between TL, related genetic variants and susceptibility to squamous cell carcinoma of the head and neck (SCCHN) in Chinese. Hence, we detected relative telomere length (RTL) by using quantitative PCR and genotyped seven selected single nucleotide polymorphisms by TaqMan allelic discrimination assay in 510 SCCHN cases and 913 controls in southeast Chinese. The results showed that RTL was significantly associated with SCCHN risk [(adjusted odds ratio (OR) = 1.19, 95% confidence interval (CI) = 1.08–1.32, P = 0.001]. Furthermore, among seven selected SNPs, only G allele of rs2736100 related to RTL in Caucasians was significantly associated with both the decreased RTL (P = 0.002) and the increased susceptibility to SCCHN in Chinese (additive model: adjusted OR = 1.17, 95%CI = 1.00–1.38, P = 0.049). These findings provide evidence that shortened TL is a risk factor for SCCHN, and genetic variants can contribute to both TL and the susceptibility to SCCHN in southeast Chinese population.\n15. Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension Lu, Xiangfeng | Wang, Laiyuan | Lin, Xu | Huang, Jianfeng | Charles Gu, C. | He, Meian | Shen, Hongbing | He, Jiang | Zhu, Jingwen | Li, Huaixing | Hixson, James E. | Wu, Tangchun | Dai, Juncheng | Lu, Ling | Shen, Chong | Chen, Shufeng | He, Lin | Mo, Zengnan | Hao, Yongchen | Mo, Xingbo | Yang, Xueli | Li, Jianxin | Cao, Jie | Chen, Jichun | Fan, Zhongjie | Li, Ying | Zhao, Liancheng | Li, Hongfan | Lu, Fanghong | Yao, Cailiang | Yu, Lin | Xu, Lihua | Mu, Jianjun | Wu, Xianping | Deng, Ying | Hu, Dongsheng | Zhang, Weidong | Ji, Xu | Guo, Dongshuang | Guo, Zhirong | Zhou, Zhengyuan | Yang, Zili | Wang, Renping | Yang, Jun | Zhou, Xiaoyang | Yan, Weili | Sun, Ningling | Gao, Pingjin | Gu, Dongfeng\n16. Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: A report from the Female Lung Cancer Consortium in Asia Machiela, Mitchell J | Hsiung, Chao Agnes | Shu, Xiao-Ou | Seow, Wei Jie | Wang, Zhaoming | Matsuo, Keitaro | Hong, Yun-Chul | Seow, Adeline | Wu, Chen | Hosgood, H Dean | Chen, Kexin | Wang, Jiu-Cun | Wen, Wanqing | Cawthon, Richard | Chatterjee, Nilanjan | Hu, Wei | Caporaso, Neil E | Park, Jae Yong | Chen, Chien-Jen | Kim, Yeul Hong | Kim, Young Tae | Landi, Maria Teresa | Shen, Hongbing | Lawrence, Charles | Burdett, Laurie | Yeager, Meredith | Chang, I-Shou | Mitsudomi, Tetsuya | Kim, Hee Nam | Chang, Gee-Chen | Bassig, Bryan A | Tucker, Margaret | Wei, Fusheng | Yin, Zhihua | An, She-Juan | Qian, Biyun | Lee, Victor Ho Fun | Lu, Daru | Liu, Jianjun | Jeon, Hyo-Sung | Hsiao, Chin-Fu | Sung, Jae Sook | Kim, Jin Hee | Gao, Yu-Tang | Tsai, Ying-Huang | Jung, Yoo Jin | Guo, Huan | Hu, Zhibin | Hutchinson, Amy | Wang, Wen-Chang | Klein, Robert J | Chung, Charles C | Oh, In-Jae | Chen, Kuan-Yu | Berndt, Sonja I | Wu, Wei | Chang, Jiang | Zhang, Xu-Chao | Huang, Ming-Shyan | Zheng, Hong | Wang, Junwen | Zhao, Xueying | Li, Yuqing | Choi, Jin Eun | Su, Wu-Chou | Park, Kyong Hwa | Sung, Sook Whan | Chen, Yuh-Min | Liu, Li | Kang, Chang Hyun | Hu, Lingmin | Chen, Chung-Hsing | Pao, William | Kim, Young-Chul | Yang, Tsung-Ying | Xu, Jun | Guan, Peng | Tan, Wen | Su, Jian | Wang, Chih-Liang | Li, Haixin | Sihoe, Alan Dart Loon | Zhao, Zhenhong | Chen, Ying | Choi, Yi Young | Hung, Jen-Yu | Kim, Jun Suk | Yoon, Ho-Il | Cai, Qiuyin | Lin, Chien-Chung | Park, In Kyu | Xu, Ping | Dong, Jing | Kim, Christopher | He, Qincheng | Perng, Reury-Perng | Kohno, Takashi | Kweon, Sun-Seog | Chen, Chih-Yi | Vermeulen, Roel C H | Wu, Junjie | Lim, Wei-Yen | Chen, Kun-Chieh | Chow, Wong-Ho | Ji, Bu-Tian | Chan, John K C | Chu, Minjie | Li, Yao-Jen | Yokota, Jun | Li, Jihua | Chen, Hongyan | Xiang, Yong-Bing | Yu, Chong-Jen | Kunitoh, Hideo | Wu, Guoping | Jin, Li | Lo, Yen-Li | Shiraishi, Kouya | Chen, Ying-Hsiang | Lin, Hsien-Chih | Wu, Tangchun | Wong, Maria Pik | Wu, Yi-Long | Yang, Pan-Chyr | Zhou, Baosen | Shin, Min-Ho | Fraumeni, Joseph F | Zheng, Wei | Lin, Dongxin | Chanock, Stephen J | Rothman, Nathaniel | Lan, Qing\n17. Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types Wang, Cheng | Gu, Yayun | Zhang, Kai | Xie, Kaipeng | Zhu, Meng | Dai, Ningbin | Jiang, Yue | Guo, Xuejiang | Liu, Mingxi | Dai, Juncheng | Wu, Linxiang | Jin, Guangfu | Ma, Hongxia | Jiang, Tao | Yin, Rong | Xia, Yankai | Liu, Li | Wang, Shouyu | Shen, Bin | Huo, Ran | Wang, Qianghu | Xu, Lin | Yang, Liuqing | Huang, Xingxu | Shen, Hongbing | Sha, Jiahao | Hu, Zhibin\n18. Potentially Functional Polymorphisms in POU5F1 Gene Are Associated with the Risk of Lung Cancer in Han Chinese Niu, Rui | Wang, Yuzhuo | Zhu, Meng | Wen, Yifan | Sun, Jie | Shen, Wei | Cheng, Yang | Zhang, Jiahui | Jin, Guangfu | Ma, Hongxia | Hu, Zhibin | Shen, Hongbing | Dai, Juncheng\nBioMed Research International 2015;2015:851320.\nPOU5F1 is a key regulator of self-renewal and differentiation in embryonic stem cells and may be associated with initiation, promotion, and progression in cancer. We hypothesized that functional polymorphisms in POU5F1 may play an important role in modifying the lung cancer risk. To test this hypothesis, we conducted a case-control study to explore the association between 17 potentially functional SNPs in POU5F1 gene and the lung cancer risk in 1,341 incident lung cancer cases and 1,982 healthy controls in a Chinese population. We found that variant alleles of rs887468 and rs3130457 were significantly associated with increased risk of lung cancer after multiple comparison (OR = 1.29, 95% CI: 1.11–1.51, Pfdr = 0.017 for rs887468; OR = 1.29, 95% CI: 1.10–1.51, Pfdr = 0.034 for rs3130457, resp.). In addition, we detected a significant interaction between rs887468 genotypes and smoking status on lung cancer risk (P = 0.017). Combined analysis of these 2 SNPs showed a significant allele-dosage association between the number of risk alleles and increased risk of lung cancer (Ptrend < 0.001). These findings indicate that potentially functional polymorphisms in POU5F1 gene may contribute to lung cancer susceptibility in a Chinese population.\n19. A functional variant in miR-155 regulation region contributes to lung cancer risk and survival Xie, Kaipeng | Ma, Hongxia | Liang, Cheng | Wang, Cheng | Qin, Na | Shen, Wei | Gu, Yayun | Yan, Caiwang | Zhang, Kai | Dai, Ningbin | Zhu, Meng | Wu, Shuangshuang | Wang, Hui | Dai, Juncheng | Jin, Guangfu | Shen, Hongbing | Hu, Zhibin\nEmerging evidence suggested that upregulation of miR-155 could serve as a promising marker for the diagnosis and prognosis of non-small cell lung cancer (NSCLC). In the present study, we genotyped rs767649 (A > T) located in miR-155 regulation region in 1341 cases and 1982 controls, and analyzed the associations of rs767649 with NSCLC risk and survival. Consequently, rs767649 exhibited the significant associations with the risk (adjusted OR = 1.12, 95% CI = 1.01–1.24, P = 0.031) and prognosis of NSCLC (adjusted HR = 1.17, 95% CI = 1.03–1.32, P = 0.014). Meanwhile, rs767649 specifically interacted with radio-chemotherapy (Pint = 0.013), and patients with both the rs767649-TT genotype and radio-chemotherapy had the highest hazard ratio (adjusted HR = 1.65, 95% CI = 1.26–2.16, P < 0.001). Furthermore, using functional assays and The Cancer Genome Atlas (TCGA) Lung Adenocarcinoma (LUAD) dataset, we found that rs767649 variant allele could increase the transcriptional activity of miR-155, which in turn facilitated tumor growth and metastasis by inhibiting HBP1, TJP1, SMAD5 and PRKAR1A expression. Our findings suggested that rs767649 A > T might contribute to the increased risk and poor prognosis of NSCLC, highlighting the importance of rs767649 in the prevention and therapy of NSCLC.\nnon-small cell lung cancer; genetic susceptibility; prognosis; miR-155\n20. Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33 Wang, Zhaoming | Zhu, Bin | Zhang, Mingfeng | Parikh, Hemang | Jia, Jinping | Chung, Charles C. | Sampson, Joshua N. | Hoskins, Jason W. | Hutchinson, Amy | Burdette, Laurie | Ibrahim, Abdisamad | Hautman, Christopher | Raj, Preethi S. | Abnet, Christian C. | Adjei, Andrew A. | Ahlbom, Anders | Albanes, Demetrius | Allen, Naomi E. | Ambrosone, Christine B. | Aldrich, Melinda | Amiano, Pilar | Amos, Christopher | Andersson, Ulrika | Andriole, Gerald | Andrulis, Irene L. | Arici, Cecilia | Arslan, Alan A. | Austin, Melissa A. | Baris, Dalsu | Barkauskas, Donald A. | Bassig, Bryan A. | Beane Freeman, Laura E. | Berg, Christine D. | Berndt, Sonja I. | Bertazzi, Pier Alberto | Biritwum, Richard B. | Black, Amanda | Blot, William | Boeing, Heiner | Boffetta, Paolo | Bolton, Kelly | Boutron-Ruault, Marie-Christine | Bracci, Paige M. | Brennan, Paul | Brinton, Louise A. | Brotzman, Michelle | Bueno-de-Mesquita, H. Bas | Buring, Julie E. | Butler, Mary Ann | Cai, Qiuyin | Cancel-Tassin, Geraldine | Canzian, Federico | Cao, Guangwen | Caporaso, Neil E. | Carrato, Alfredo | Carreon, Tania | Carta, Angela | Chang, Gee-Chen | Chang, I-Shou | Chang-Claude, Jenny | Che, Xu | Chen, Chien-Jen | Chen, Chih-Yi | Chen, Chung-Hsing | Chen, Constance | Chen, Kuan-Yu | Chen, Yuh-Min | Chokkalingam, Anand P. | Chu, Lisa W. | Clavel-Chapelon, Francoise | Colditz, Graham A. | Colt, Joanne S. | Conti, David | Cook, Michael B. | Cortessis, Victoria K. | Crawford, E. David | Cussenot, Olivier | Davis, Faith G. | De Vivo, Immaculata | Deng, Xiang | Ding, Ti | Dinney, Colin P. | Di Stefano, Anna Luisa | Diver, W. Ryan | Duell, Eric J. | Elena, Joanne W. | Fan, Jin-Hu | Feigelson, Heather Spencer | Feychting, Maria | Figueroa, Jonine D. | Flanagan, Adrienne M. | Fraumeni, Joseph F. | Freedman, Neal D. | Fridley, Brooke L. | Fuchs, Charles S. | Gago-Dominguez, Manuela | Gallinger, Steven | Gao, Yu-Tang | Gapstur, Susan M. | Garcia-Closas, Montserrat | Garcia-Closas, Reina | Gastier-Foster, Julie M. | Gaziano, J. Michael | Gerhard, Daniela S. | Giffen, Carol A. | Giles, Graham G. | Gillanders, Elizabeth M. | Giovannucci, Edward L. | Goggins, Michael | Gokgoz, Nalan | Goldstein, Alisa M. | Gonzalez, Carlos | Gorlick, Richard | Greene, Mark H. | Gross, Myron | Grossman, H. Barton | Grubb, Robert | Gu, Jian | Guan, Peng | Haiman, Christopher A. | Hallmans, Goran | Hankinson, Susan E. | Harris, Curtis C. | Hartge, Patricia | Hattinger, Claudia | Hayes, Richard B. | He, Qincheng | Helman, Lee | Henderson, Brian E. | Henriksson, Roger | Hoffman-Bolton, Judith | Hohensee, Chancellor | Holly, Elizabeth A. | Hong, Yun-Chul | Hoover, Robert N. | Hosgood, H. Dean | Hsiao, Chin-Fu | Hsing, Ann W. | Hsiung, Chao Agnes | Hu, Nan | Hu, Wei | Hu, Zhibin | Huang, Ming-Shyan | Hunter, David J. | Inskip, Peter D. | Ito, Hidemi | Jacobs, Eric J. | Jacobs, Kevin B. | Jenab, Mazda | Ji, Bu-Tian | Johansen, Christoffer | Johansson, Mattias | Johnson, Alison | Kaaks, Rudolf | Kamat, Ashish M. | Kamineni, Aruna | Karagas, Margaret | Khanna, Chand | Khaw, Kay-Tee | Kim, Christopher | Kim, In-Sam | Kim, Jin Hee | Kim, Yeul Hong | Kim, Young-Chul | Kim, Young Tae | Kang, Chang Hyun | Jung, Yoo Jin | Kitahara, Cari M. | Klein, Alison P. | Klein, Robert | Kogevinas, Manolis | Koh, Woon-Puay | Kohno, Takashi | Kolonel, Laurence N. | Kooperberg, Charles | Kratz, Christian P. | Krogh, Vittorio | Kunitoh, Hideo | Kurtz, Robert C. | Kurucu, Nilgun | Lan, Qing | Lathrop, Mark | Lau, Ching C. | Lecanda, Fernando | Lee, Kyoung-Mu | Lee, Maxwell P. | Le Marchand, Loic | Lerner, Seth P. | Li, Donghui | Liao, Linda M. | Lim, Wei-Yen | Lin, Dongxin | Lin, Jie | Lindstrom, Sara | Linet, Martha S. | Lissowska, Jolanta | Liu, Jianjun | Ljungberg, Börje | Lloreta, Josep | Lu, Daru | Ma, Jing | Malats, Nuria | Mannisto, Satu | Marina, Neyssa | Mastrangelo, Giuseppe | Matsuo, Keitaro | McGlynn, Katherine A. | McKean-Cowdin, Roberta | McNeill, Lorna H. | McWilliams, Robert R. | Melin, Beatrice S. | Meltzer, Paul S. | Mensah, James E. | Miao, Xiaoping | Michaud, Dominique S. | Mondul, Alison M. | Moore, Lee E. | Muir, Kenneth | Niwa, Shelley | Olson, Sara H. | Orr, Nick | Panico, Salvatore | Park, Jae Yong | Patel, Alpa V. | Patino-Garcia, Ana | Pavanello, Sofia | Peeters, Petra H. M. | Peplonska, Beata | Peters, Ulrike | Petersen, Gloria M. | Picci, Piero | Pike, Malcolm C. | Porru, Stefano | Prescott, Jennifer | Pu, Xia | Purdue, Mark P. | Qiao, You-Lin | Rajaraman, Preetha | Riboli, Elio | Risch, Harvey A. | Rodabough, Rebecca J. | Rothman, Nathaniel | Ruder, Avima M. | Ryu, Jeong-Seon | Sanson, Marc | Schned, Alan | Schumacher, Fredrick R. | Schwartz, Ann G. | Schwartz, Kendra L. | Schwenn, Molly | Scotlandi, Katia | Seow, Adeline | Serra, Consol | Serra, Massimo | Sesso, Howard D. | Severi, Gianluca | Shen, Hongbing | Shen, Min | Shete, Sanjay | Shiraishi, Kouya | Shu, Xiao-Ou | Siddiq, Afshan | Sierrasesumaga, Luis | Sierri, Sabina | Loon Sihoe, Alan Dart | Silverman, Debra T. | Simon, Matthias | Southey, Melissa C. | Spector, Logan | Spitz, Margaret | Stampfer, Meir | Stattin, Par | Stern, Mariana C. | Stevens, Victoria L. | Stolzenberg-Solomon, Rachael Z. | Stram, Daniel O. | Strom, Sara S. | Su, Wu-Chou | Sund, Malin | Sung, Sook Whan | Swerdlow, Anthony | Tan, Wen | Tanaka, Hideo | Tang, Wei | Tang, Ze-Zhang | Tardon, Adonina | Tay, Evelyn | Taylor, Philip R. | Tettey, Yao | Thomas, David M. | Tirabosco, Roberto | Tjonneland, Anne | Tobias, Geoffrey S. | Toro, Jorge R. | Travis, Ruth C. | Trichopoulos, Dimitrios | Troisi, Rebecca | Truelove, Ann | Tsai, Ying-Huang | Tucker, Margaret A. | Tumino, Rosario | Van Den Berg, David | Van Den Eeden, Stephen K. | Vermeulen, Roel | Vineis, Paolo | Visvanathan, Kala | Vogel, Ulla | Wang, Chaoyu | Wang, Chengfeng | Wang, Junwen | Wang, Sophia S. | Weiderpass, Elisabete | Weinstein, Stephanie J. | Wentzensen, Nicolas | Wheeler, William | White, Emily | Wiencke, John K. | Wolk, Alicja | Wolpin, Brian M. | Wong, Maria Pik | Wrensch, Margaret | Wu, Chen | Wu, Tangchun | Wu, Xifeng | Wu, Yi-Long | Wunder, Jay S. | Xiang, Yong-Bing | Xu, Jun | Yang, Hannah P. | Yang, Pan-Chyr | Yatabe, Yasushi | Ye, Yuanqing | Yeboah, Edward D. | Yin, Zhihua | Ying, Chen | Yu, Chong-Jen | Yu, Kai | Yuan, Jian-Min | Zanetti, Krista A. | Zeleniuch-Jacquotte, Anne | Zheng, Wei | Zhou, Baosen | Mirabello, Lisa | Savage, Sharon A. | Kraft, Peter | Chanock, Stephen J. | Yeager, Meredith | Landi, Maria Terese | Shi, Jianxin | Chatterjee, Nilanjan | Amundadottir, Laufey T.\n21. Mitochondria-related miR-151a-5p reduces cellular ATP production by targeting CYTB in asthenozoospermia Zhou, Ran | Wang, Rong | Qin, Yufeng | Ji, Juan | Xu, Miaofei | Wu, Wei | Chen, Minjian | Wu, Di | Song, Ling | Shen, Hongbing | Sha, Jiahao | Miao, Dengshun | Hu, Zhibin | Xia, Yankai | Lu, Chuncheng | Wang, Xinru\nScientific Reports 2015;5:17743.\n22. Genome-wide association study identifies two new susceptibility loci for colorectal cancer at 5q23.3 and 17q12 in Han Chinese Jiang, Kewei | Sun, Yimin | Wang, Cheng | Ji, Jiafu | Li, Yaoping | Ye, Yingjiang | Lv, Liang | Guo, Yong | Guo, Sutang | Li, Hai | Zhang, Lianhai | Zhou, Yanbing | Jiang, Bo | Ren, Yonghong | Xu, Youchun | Yang, Xiongfei | Liu, Hongxia | Wang, Yirui | Shen, Zhanlong | Qin, Wenyan | Guo, Peng | Jiang, Yuyang | Hu, Zhibin | Shen, Hongbing | Cheng, Jing | Yang, Yinxue | Wang, Shan\nGWAS; colorectal cancer; association\n23. Hepatitis B virus genotype, mutations, human leukocyte antigen polymorphisms and their interactions in hepatocellular carcinoma: a multi-centre case-control study Wen, Juan | Song, Ci | Jiang, Deke | Jin, Tianbo | Dai, Juncheng | Zhu, Liguo | An, Jiaze | Liu, Yao | Ma, Shijie | Qin, Na | Liang, Cheng | Chen, Jiaping | Jiang, Yue | Yang, Linlin | Liu, Jibin | Liu, Li | Geng, Tingting | Chen, Chao | Jiang, Jie | Chen, Jianguo | Zhu, Fengcai | Zhu, Yefei | Yu, Long | Shen, Hongbing | Zhai, Xiangjun | Xu, Jianfeng | Hu, Zhibin\nScientific Reports 2015;5:16489.\nThree genome-wide association studies (GWAS) have been conducted on the genetic susceptibility of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), two of which consistently identified tagging single nucleotide polymorphisms (SNPs) around HLA-DQ/DR. In contrast, large multi-centre association studies between HBV genotype, mutations and the risk of HCC are relatively rare, and their interactions with host variants are even less. We performed a multi-centre study of 1,507 HBV-related HCC cases and 1,560 HBV persistent carriers as controls to evaluate the effects of HBV genotype, mutations, GWAS-identified HLA-DQ/DR SNPs (rs9272105 and rs9275319) and their interactions on HCC risk. We found HBV genotype C was more frequent in HBV-related HCC. And 11 HBV hotspot mutations were independently and significantly associated with HCC risk. We also detected significant interactions of rs9272105 with both the HBV genotype and mutations. Through stepwise regression analysis, HBV genotype, the 11 mutations, HLA-DQ/DR SNPs, and the interaction of rs9272105 with mutation A1752G were all entered into the HCC prediction model, and the area under the curve for the panel including the HLA-DQ/DR SNPs, HBV genotype and mutations was 0.840. The HBV genotype, the mutations and the HLA-DQ/DR SNPs may serve as biomarkers for the surveillance of HBV persistent carriers.\n24. Mitochondria-related miR-141-3p contributes to mitochondrial dysfunction in HFD-induced obesity by inhibiting PTEN Ji, Juan | Qin, Yufeng | Ren, Jing | Lu, Chuncheng | Wang, Rong | Dai, Xiuliang | Zhou, Ran | Huang, Zhenyao | Xu, Miaofei | Chen, Minjian | Wu, Wei | Song, Ling | Shen, Hongbing | Hu, Zhibin | Miao, Dengshun | Xia, Yankai | Wang, Xinru\nScientific Reports 2015;5:16262.\n25. Polymorphisms in microRNAs are associated with survival in non-small cell lung cancer Zhao, Yang | Wei, Qingyi | Hu, Lingming | Chen, Feng | Hu, Zhibin | Heist, Rebecca S. | Su, Li | Amos, Christopher I. | Shen, Hongbing | Christiani, David C.\nCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2014;23(11):2503-2511.\nMicroRNAs (miRNAs) play important roles in the regulation of eukaryotic gene expression and are involved in human carcinogenesis. Single nucleotide polymorphisms (SNPs) in miRNA sequence may alter miRNA functions in gene regulation, which, in turn, may affect cancer risk and disease progression.\nWe conducted an analysis of associations of 142 miRNA SNPs with non-small cell lung cancer (NSCLC) survival using data from a genome-wide association study (GWAS) in a Caucasian population from the Massachusetts General Hospital (Boston, MA, US) including 452 early-stage and 526 late-stage NSCLC cases. Replication analyses were further performed in two external populations, one Caucasian cohort from The University of Texas MD Anderson Cancer Center (Houston, TX, US) and one Han Chinese cohort from Nanjing, China.\nWe identified 7 significant SNPs in the discovery set. Results from the independent Caucasian cohort demonstrated that the C allele of rs2042253 (has-miRNA-5197) was significantly associated with decreased risk for death among the late-stage NSCLC patients (discovery set: HR=0.80, P=0.007; validation set: HR=0.86, P=0.035; combined analysis: HR=0.84, P=0.001).\nThese findings provide evidence that some miRNA SNPs are associated with NSCLC survival and can be used as predictive biomarkers.\nThis study provided an estimate of outcome probability for survival experience of NSCLC patients, which demonstrates that genetic factors, as well as classical non-genetic factors, may be used to predict individual outcome.\nmicro RNA lung cancer; biomarkers; predictors of survival


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url: =On the Optimized Teaching of Basketball among PE Majors in College--《Journal of Fuling Teachers College》2003年05期\n《Journal of Fuling Teachers College》 2003-05\nOn the Optimized Teaching of Basketball among PE Majors in College\nGUO Li (Department of Physical Education, Fuling Teachers College, Chongqing 408003, China)\nWith the all-sided reform of education, it is of great significance to explore the teaching of basketball in colleges. The optimized teaching is the core of basketball teaching. In the light of the characteristics of basketball teaching in China, the writer of this article provides some suggestions on how to choose and make use of the forms and methods of optimized teaching so as to achieve the optimized effect.\n1 XING Zhong-you Department of Physical Education,Xuchang College,Xuchang 461000,Henan China;Application and Experimental Study on Different Mutual Teaching Method in Basketball Class[J];Bulletin of Sport Science & Technology;2008-09\n2 CHENG Lin LIU Jian (Chengdu Institute of Physical Education Sichuan 610041);Create the Teaching Mode of“Broad, Moderate, Flexible” Optimizing Sports Talents Training[J];Journal of Chengdu Physical Education Institute;2001-02\n3 Chen Qi et al (South China Normal University, guangzhou, China 510631);Physical Education Curriculum in Today and Its Development Trend[J];Sport Science;1998-05\n3 Feng Shoudong * Zhou Ke (Department of P.E,Henan University,Henan 475001);An Experimental Research on Ball Games Courses Teaching Integrative Reform In P.E Department[J];Journal of Anhui Sports Science;2002-03\n4 Sun Zhixin Nie Zhiqiang(College of P.E.Liaocheng University,LiaoCheng252059);A Probe Into Improving The Current Testing Method & Standard Of The Athletic Teaching[J];Journal of Anhui Sports Science;2003-03\n5 Wang Xiaoling(The Educational Bureau In The City of Chizhou,Chizhou Anhui 247000);The Problems And Strategies Of The P.E. Teaching Reform In Current Primary And Middle Schools[J];Journal of Anhui Sports Science;2006-05\n6 NIU Yong gang (P.E.Department of Anyang Teachers College,Anyang 455002,China);Emphasis Should be Paid on Health Consciousness of Students's in College Physical Education[J];Journal of Aayang Teachers College;2000-04\n7 QIAN Jie;Discussion on Physical Education Teaching Organization Mode in Colleges and Universities[J];JOURNAL OF BEIJING UNIVERSITY OF PHYSICAL EDVCATION;2000-01\n8 MA Yong-zhan (Dept. of PE, Taizhou Teachers Training School of Zhejiang Province, Taizhou 317000, China);Research on Factors Composing Physical Education Course in Chinese Universities and Measures for its Development[J];JOURNAL OF BEIJING UNIVERSITY OF PHYSICAL EDVCATION;2000-02\n9 GONG De gui 1,Gao Yan song 2,TAN Xiao yong 1,MAO Zhi he 1,HUANG Zhen 3,ZHANG Shi wei 4 (1.Dept. of PE, Changde Teachers College, Changde 415000, Hunan, China;2.Teaching and Research Dept. of PE, Jilin University, Chang chun, 130023,Jilin, Ch;Research on Evaluation Standards of Specialized Courses of Physical Education in Teachers Colleges in the 21st Century[J];Journal of Beijing University of Physical Education;2000-04\n10 XU Ming rong, JIANG Ling, ZHOU Zhang bin, LIU Zhong qing, ZHAO Yang dong, ZHUANG Qi lin (Dept. of PE, Guangxi University, Nanning 530004, Guangxi, China);Research on Implement of Inside and Outside-class Integrative Pattern of Club System in Physical Education Courses of Colleges and Universities[J];Journal of Beijing University of Physical Education;2001-03\n1 WANG Yong,ZHU Bin-bin;About the Basketball Course in Colleges[J];Journal of Anhui Textile Vocational Technical Institute;2005-04\n3 LIU Min (Department of P.E., Guangxi Physical Education College, Naning 530012, Guangxi China);Research on the Reform of Theoretical Teaching of Basketball Major Course[J];Journal of Beijing University of Physical Education;2005-09\n4 LI Qian1,WU Ai-li1,XU Bo2 (1.Hunan Institute of Business,410205,China;2.Beijing Sport University,Beijing 100084,China);Research on the Designing Methods of the Standard System of Basketball Teaching Materials in P.E Colleges and Universities[J];Journal of Beijing Sport University;2007-04\n5 WANG Bao-cheng (Department of Science and Technology,Capital Institute of Physical Education,Beijing 100088,China);Arrangements and Selection of Teaching Contonts in School Physical Education[J];Journal of Beijing Teachers College of Physical Education;2004-03\n6 ZHANG Xian-gui ( College of Physical Education, Dalian University, Dalian 116622, China);Research on optimal basketball teaching made of physical education speciality[J];Journal of Dalian University;2004-03\n7 TAN Da-shun;Brief Discussion on the Developing Trend of Teaching Methods in the 21~nt Century[J];Journal of Dali College;2002-06\n8 ZHANG Guang jun (College of Educational Science,Tianjin Normal University, Tianjin 300074, China);On the Qualitative Regularity of Teaching-Learning Process[J];Journal of Educational Science of Hunan Normal University;2003-01\n9 LIU You-ce (Heilongjiang Institute of Science and Technology,Harbin 150027,Heilongjiang China);The Utilization of Graduation Fluctuation Law in Basketball Teaching[J];Journal of Harbin Institute of Physical Education;2007-03\n10 XIONG He ping (Beijing Center for Legal Protection against Illegitimate Competition, Beijing 100080, China);A Critique: Rethinking the Research on the Nature of Teaching Process in the Past Two Decades in China[J];Education and Modernization;2001-03


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url: =Jeff Leibow | Article Archives | San Francisco News and Events | SF Weekly\nre: Jeff Leibow\nThough it's essentially a revue of more than 30 Stephen Sondheim songs from his classic musicals (such as Follies, Company, and A Little Night Music), Putting It Together still tells the somewhat coherent (if thin) story of the intoxicating rush…\nby Nathaniel Eaton August 2, 2006 Tags: Stagecap, Columns, Stephen Sondheim, Follies , Company, Mary-Pat Green, Jeff Leibow\nWhy do people write silly musicals about love? And why, come to think of it, do people sit through them? Even jaded New York audiences can't seem to get enough of the most obvious musical nonsense about dating, romance, marriage,…\nby Michael Scott Moore August 18, 2004 Tags: Stage, Stage, Joe DiPietro, Danielle Thys, Colin Thomson, Jeff Leibow


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url: =Fuzzy optimization of tolerance in CAD/CAPP integration--《Journal of Zhejiang University(Engineering Science)》2001年01期\nFuzzy optimization of tolerance in CAD/CAPP integration\nLIU Yu-sheng,YANG Jiang-xin,WU Zhao-tong\_;(Production Engineering Institute of Zhejiang Uni., Hangzhou 310027, China)\nFuzzy factors in CAD/CAPP concurrent tolerance design are analyzed. The result shows that fuzzy factors are of objectiveness and unavoidableness in concurrent tolerance. A new mathematical model was presented for design and manufacturing tolerance design. To solve this model, two steps are used. The first step is to transform the fuzzy optimal model to non-fuzzy optimal model by using a kind of membership function which can change the absolute limit boundary to a transitional one. The second step is to solve the non-fuzzy optimal model using Monte Carlo simulation method. An example is given to illustrate the proposed model.\n【Fund】： 国家自然科学基金资助项目 !(5 970 5 0 2 2 )\n1 XU Xu-song,YANG Jiang-xin,CAO Yan-long,MAO Jian(Institute of Modern Manufacturing Engineering,Zhejiang University,Hangzhou 310027,China);Manufacturing error modeling based on homogeneous transformation[J];浙江大学学报(工学版);2008-06\n2 Cao Yanlong Yang Jiangxin Wu Zhaotong Ying Yibin(Zhejiang University) Wang Yifeng(Zhejiang University of Science and Technology);Fuzzy Quality Loss Function Model[J];农业机械学报;2004-04\n3 YANG Bo 1, 2 , HUANG Ke zheng 2 ,CHEN Hong wu 2 ( 1 College of Mechanical Engineering, Jinan University, Jinan 250022; 2 College of Mechanical Engineering, Shangdong University, Jinan 250061);A Review of the Optimal Design Methods in Design for Assembly(DFA)[J];机械科学与技术;2004-07\n4 CAO Yan-long~1, YANG Jiang-xin~1, WU Zhao-tong~1, WU Li-qun~2(1.Institute of Modern Manufacturing Engineering, Zhejiang University, Hangzhou 310027, China;2.Hangzhou Institute of Electronic Industry, Hangzhou 310037, China);Robust tolerance design based on fuzzy quality loss[J];浙江大学学报(工学版);2004-01\n1 Yang Jiangxin Wu Zhaotong (Zhejiang University);FUZZY EXPERT CONSULTANT SYSTEM FOR DESIGNOF COMPONENTS FITTING[J];机械工程学报;1997-04\n1 ;Design Method of Mechanical Part Fitting Based on Evidential Reasoning[J];航空制造技术;2010-05\n2 LIU Yu-sheng,YANG Jiang-xin,WU Zhao-tong\_;(Production Engineering Institute of Zhejiang Uni., Hangzhou 310027, China);Fuzzy optimization of tolerance in CAD/CAPP integration[J];浙江大学学报(工学版);2001-01\n3 Yang Jiangxin; Liu Yusheng ; Tan Jianrong; Wu Zhaotong (Production Engineering Institute, Zhejiang University);A CAD MODEL FOR FUZZY CONCURRENT TOLERANCE[J];Chinese Journal of Mechanical Engineering(English Edition);2000-02\n1 Huang Meifa Zhong Yanru Guilin University of Electronic Technology, Guilin,541004;A New Model for Concurrent Tolerancing in CAD System[J];中国机械工程;2004-18\n2 CAO Yan-long~1, YANG Jiang-xin~1, WU Zhao-tong~1, WU Li-qun~2(1.Institute of Modern Manufacturing Engineering, Zhejiang University, Hangzhou 310027, China;2.Hangzhou Institute of Electronic Industry, Hangzhou 310037, China);Robust tolerance design based on fuzzy quality loss[J];浙江大学学报(工学版);2004-01\n3 Hu Jie Xiong Guangleng (Tsinghua University) Wu Zhaotong (Zhejiang University);STUDY ON TOLERANCE DESIGN BASED ON VARIATIONAL GEOMETRIC CONSTRAINS NETWORK[J];机械工程学报;2003-05\n4 HE Shan 1,XIONG Guang-leng 1,ZENG Qin-liang 1,FAN Wen-hui 1, YUE Yu-hua 2,ZHANG Chun-heng 2,BAO Jian-wen 2 ( 1 The National CIMS/ERC, Tsinghua University, Beijing 100084; 2 Qiqihaer Rolling Stocks Co.Ltd, Qiqihaer 161002);A Method for Estimating Product Assembly Cost Based on Neural Networks[J];机械科学与技术;2002-04\n5 ZHANG Weijun(Shanghai Jiaotong University,Shanghai, China)JIA Chuansheng YANG Ruqing;Robotic Assembly Task Planning Based on Timed Petri Nets[J];中国机械工程;2002-14\n6 YANG Peng, LIU Ji-hong,GUAN Qiang (CAD Center, Huazhong Univ. of Science and Technology, Wuhan 430074, China);An Improved Genetic Algorithm for Assembly Sequence Optimization[J];计算机集成制造系统-CIMS;2002-06\n7 GUO Huixin(Changde Teachers University,Changde,Hunan);Study on the Fuzzy Robustness of Product Quality and Method of Fuzzy Robust Optimal Design[J];中国机械工程;2002-03\n8 SHU Qi lin et al (Department of Mechanical Engineering Shenyang Institute of Technology);Establishment and realization of assemblability analysis and evaluation model at the level of component part[J];机械设计;2001-12\n9 Wang Junping 1,2 , Tao Hua 1, Li Jianjun 2 1.Northwestern Polytechnical University, Xi′an 710072; 2.Luoyang Photoelectric Technique Development Center, Luoyang 471009;A Multiple-Parameter Quality Loss Model[J];西北工业大学学报;2001-03\n10 Zhang Weijun Wei Changqing Yang Ruqing (Shanghai Jiaotong University);SYNCHRONIZED PETRI NETS MODEL FOR ROBOTIC ASSEMBLY STATES TRANSITION CONTROL[J];机械工程学报;2001-04\n1 HUANG Meifa;TANG Zhemin;SUN Yonghou;GONG Wenfeng;ZHANG Zhengpo;School of Mechanical and Electrical Engineering,Guilin University of Electronic Technology;Guangxi Key Laboratory of Manufacturing System and Manufacturing Technology;Guilin Guanglu Measuring Instrument Co.,Ltd.;;Assembly tolerance modeling based on auxiliary assembly joints[J];计算机集成制造系统;2015-08\n2 QI Zhenchao;ZHANG Kaifu;LI Yuan;CHENG Hui;The Key Lab of Contemporary Design and Integrated Manufacturing Technology,Ministry of Education,Northwestern Polytechnical University;School of Mechanical Engineering,Northwestern Polytechnical University;;Analysis and optimization for locating errors of large wing panel during automatic drilling and riveting[J];航空学报;2015-10\n3 Wang Weifeng;Shi Jianghuan;Li Beibei;Ningbo Institute of Measurement and Testing Technology;;An evaluation method of detection quality based on MCP and RM[J];分析仪器;2015-01\n4 ZHONG Yanru;WANG Bingqing;HUANG Meifa;QIN Yuchu;WU Shiwei;Guangxi Colleges and Universities Key Laboratory of Intelligent Processing of Computer Image and Graphics,Guilin University of Electronic Technology;Henan Local Taxation Management Cadre School;School of Mechanical and Electrical Engineering,Guilin University of Electronic Technology;School of Mechanical Science and Engineering,Huazhong University of Science and Technology;;Functional tolerance analysis based on description logic[J];计算机集成制造系统;2015-08\n5 ZHAO Man;MAO Jian;College of Mechanical Engineering,Shanghai University of Engineering Science;;Research on model of assembly tolerance for manufacturing process[J];工程设计学报;2014-06\n6 ZHAO Xianfu;ZONG Min;ZHAO Xuan;CAO Shuang;ZHANG Yufeng;;Industrial Bolt Hole Space Position Detection Based on Three-dimensional Laser Scanning Technology[J];测绘通报;2014-03\n7 WANG Yi-feng;WANG Chen-chen;CAO Yan-long;YANG Jiang-xin;Zhejiang University of Science and Technology;Institute of Modern Manufacturing Engineering,Zhejiang University;;CNC Machine Tool Geometric Error Odentification Study[J];机械设计与制造;2014-02\n8 MENG Biao;WANG Bo;Key Laboratory of Aeronautical Digital Manufacturing Processes,Fundamental Science for National Defense,Shenyang Aerospace University;;Improvement of Engineering Dimension Driving Principle and Its Application to Tolerance Analysis[J];航空学报;2014-06\n9 Zhao Yanming1,3,Guo Yinfu2,Wen Zejun2,Liu Qiao2(1.School of Mechanical and Electrical Engineering,Central South University,Changsha 410083,China;2.Hunan University of Science and Technology,Hunan Provincial Key Laboratory of Health Maintenance for Mechanical Equipment,Xiangtan 411201,China;3.School of Information and Electrical Engineering,Hunan University of Science and Technology,Xiangtan 411201,China);Modeling Present Worth of Product Quality Losses of LTB Characteristic Based on Service Life Distribution[J];机械设计与研究;2013-04\n10 FENG Yan,HONG Jun,GUO Jun-kang,WANG Yong(State Key Laboratory for Manufacturing Systems Engineering,Xi'an Jiaotong University,Xi'an 710049,China);Tolerance modeling of working load based on geometrical product specifications[J];计算机集成制造系统;2013-07\n1 Liu Yusheng; Wu Zhaotong; Yang Jiangxin (Institute of Production Engineering, Zhjiang University, Hangzhou, 310027 );A research of computer aided tolerance optinal design based on cost models[J];浙江大学学报(自然科学版);1995-06


url: =Yinni di shang zhan he shang wu lü xing (Book, 1985) [WorldCat.org]\nI thought you might be interested in this item at http://www.worldcat.org/oclc/15409490 Title: Yinni di shang zhan he shang wu lü xing Publisher: Taibei Shi : Zhonghua Minguo dui wai mao yi fa zhan xie hui, min guo 74  OCLC:15409490\nYinni di shang zhan he shang wu lü xing\n撰編中華民國駐耶加逹中華商會經濟組. ; ; Zhonghua Minguo zhu Yejiada Zhonghua shang hui. Jing ji zu.\n中華民國對外貿易發展協會, Taibei Shi : Zhonghua Minguo dui wai mao yi fa zhan xie hui, min guo 74 \nMao xie cong gan., Mao yi shi wu lei ;, bian hao 74-316.\nFairs -- Indonesia.\nii, 34 pages : map ; 27 cm.\nzhuan bian Zhonghua Minguo zhu Yejiada Zhonghua shang hui jing ji zu.\nYinni di shang zhan he shang wu lü xing". 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url: =1 March 2013 Osteology of Concavispina biseridens (Reptilia, Thalattosauria) from the Xiaowa Formation (Carnian), Guanling, Guizhou, China\nJun Liu, Li-Jun Zhao, Chun Li, Tao He\nJun Liu,1 Li-Jun Zhao,2 Chun Li,1 Tao He2\n1Key Laboratory of Evolutionary Systematics of Vertebrates, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing 100044, China, < >; and liujun@ivpp.ac.cn\n2Zhejiang Museum of Natural History, Hangzhou 310012, China\nJ. of Paleontology, 87(2):341-350 (2013). https://doi.org/10.1666/12-059R1.1\nJun Liu, Li-Jun Zhao, Chun Li, and Tao He "Osteology of Concavispina biseridens (Reptilia, Thalattosauria) from the Xiaowa Formation (Carnian), Guanling, Guizhou, China," Journal of Paleontology 87(2), 341-350, (1 March 2013). https://doi.org/10.1666/12-059R1.1\nJun Liu, Li-Jun Zhao, Chun Li, Tao He "Osteology of Concavispina biseridens (Reptilia, Thalattosauria) from the Xiaowa Formation (Carnian), Guanling, Guizhou, China," Journal of Paleontology, 87(2), 341-350, (1 March 2013)


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url: =Rui Hua - researchr alias\nPublications by 'Rui Hua'\nUnsupervised Video Highlight Extraction via Query-related Deep TransferHan Wang, Huangyue Yu, Pei Chen, Rui Hua, Chuyi Yan, Ling Zou. icpr 2018: 2971-2976 [doi]\nMultiresolution eXtended Free-Form Deformations (XFFD) for non-rigid registration with discontinuous transformsRui Hua, Jose M. Pozo, Zeike A. Taylor, Alejandro F. Frangi. mia, 36:113-122, 2017. [doi]\nAccurate personal ultraviolet dose estimation with multiple wearable sensorsJinyang Li, Yongpan Liu, Hehe Li, Rui Hua, Chun Jason Xue, Hyung Gyu Lee, Huazhong Yang. bsn 2016: 347-352 [doi]\nA compare-and-select error tolerant scheme for nonvolatile processorsZhibo Wang, Rui Hua, Yongpan Liu, Huazhong Yang. NANOARCH 2016: 21-22 [doi]\nAutomated Quality Assessment of Cardiac MR Images Using Convolutional Neural NetworksLe Zhang, Ali Gooya, Bo Dong, Rui Hua, Steffen Petersen, Pau Medrano-Gracia, Alejandro F. Frangi. miccai 2016: 138-145 [doi]\nDiscontinuous nonrigid registration using extended free-form deformationsRui Hua, Jose M. Pozo, Zeike A. Taylor, Alejandro F. Frangi. miip 2015: [doi]\nLearning to Detect Stent Struts in Intravascular UltrasoundFrancesco Ciompi, Rui Hua, Simone Balocco, Marina Alberti, Oriol Pujol, Carles Caus, Josepa Mauri, Petia Radeva. ibpria 2013: 575-583 [doi]\npCloud: An Adaptive I/O Resource Allocation Algorithm with Revenue Consideration over Public CloudsJianzong Wang, Yanjun Chen, Daniel Gmach, Changsheng Xie, Jiguang Wan, Rui Hua. GPC 2012: 16-30 [doi]\nRO-BURST: A Robust Virtualization Cost Model for Workload Consolidation over CloudsJianzong Wang, Rui Hua, Yifeng Zhu, Jiguang Wan, Changsheng Xie, Yanjun Chen. ccgrid 2012: 490-497 [doi]\nC-IRR: An Adaptive Engine for Cloud Storage Provisioning Determined by Economic Models with Workload Burstiness ConsiderationJianzong Wang, Rui Hua, Yifeng Zhu, Changsheng Xie, Peng Wang, Weijiao Gong. nas 2012: 79-83 [doi]\nSecurity Analysis of Authentication Schemes in m-Commerce based on Fuzzy Comprehensive EvaluationRui Hua, Runtong Zhang, Dandan Li. iciso 2010: 245-251


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url: =Study on the damage of the underground cavern caused by blasting waves--《Journal of China Coal Society》2011年S2期\n《Journal of China Coal Society》 2011-S2\nStudy on the damage of the underground cavern caused by blasting waves\nMU Chao-min1,2,3,QI Juan4(1.School of Energy Resources and Safety,Anhui University of Science and Technology,Huainan 232001,Anhui,China;2.Key Lab of Mining Coal Safety and Efficiently Constructed by Anhui Province and Ministry of Education,Huainan 232001,China;3.Luoyang Institute of Hydraulic Engineering and Technology,Luoyang 470123,China;4.Center of Modern Educational Technology,Anhui University of Science and Technology,Huainan 232001,China)\nThe tension and compression damage constitutive model was established based on the theory of continuum damage mechanics.Using the model that was implemented into the nonlinear dynamic finite element program,LS-dyna.The tension and compression damage caused by blasting waves in rock around the underground cavern was simulated.The results show that the rock bolts can improve the anti-explosion ability of the underground cavern.The damage direction is changed and the cracks are prohibited by the rock bolts so that damage can not penetrate rock bolts forming damage in the rock around the underground cavern and meanwhile the tensile strength of the rock around cavern is improved by the rock bolts.\n【CateGory Index】： TD354\n2 LI Yong-chi*, YAO Lei, SHEN Jun, HU Xiu-zhang (University of Science and Technology of China, Heifei230027, Anhui, China);Insulation effect of the cavity on stress wave[J];Explosion and Shock Waves;2005-03\n4 GU Jincai1,CHEN Anmin1,XU Jingmao1,ZHAO Hongling2,ZHANG Xiangyang1,GU Leiyu1,3,MING Zhiqing1(1.The Third Scientific Research Institute of the Corps of Engineers,General Staff of PLA,Luoyang,Henan 471023,China;2.Department of Civil Engineering,Luoyang Institute of Science and Technology,Luoyang,Henan 471023,China;3.Department of Geotechnical Engineering,Tongji University,Shanghai 200092,China);MODEL TEST STUDY OF FAILURE PATTERNS OF ANCHORED TUNNEL SUBJECTED TO EXPLOSION LOAD[J];Chinese Journal of Rock Mechanics and Engineering;2008-07\n5 WANG Guang-yong1,2,GU Jin-cai3,CHEN An-min3,XU Jing-mao3,ZHANG Xiang-yang3(1.School of Civil Engineering,Henan Polytechnic University,Jiaozuo 454000,China;2.Department of Modern Mechanics,University of Science and Technology of China,Hefei 230026,China;3.The Third Research Institute of the Corps of Engineers,General Staff of PLA,Luoyang 471023,China);Model tests on anti-explosion anchoring effect of tunnels reinforced by dense bolts at arch top[J];Chinese Journal of Geotechnical Engineering;2009-03\n6 ZHANG Liang-liang1,XIA Yuan-you1,GU Jin-cai2(1.School of Civil Engineering and Architecture,Wuhan University of Technology,Wuhan 430070,China;2.Third Research Institute of the Corps of Engineering,General Staff of PLA,Luoyang 471023,China);Stress characteristics of prestressed anchor cables under explosive waves[J];Chinese Journal of Geotechnical Engineering;2009-07\n7 WANG Zhi-liang, LI Yong-chi (University of Science and Technology of China, Hefei 230027, China);Study on diffracting and screening effects of cavities on axial stress waves in defense layer[J];Rock and Soil Mechanics;2005-08\n1 Tian Qiang1,Zheng Yunmu1,Wang Qifan1,Feng Guoxiang2(1.Depaartment of Architecture & Civil Engineering,LEU,Chongqing 401331,China;2.Engineering Research and Design Institute,Chengdu Military Region,Kunming 650222,China);The Damage Test Investigation of Underground Structure Heads Subjected to Precision Strikes[J];Chinese Journal of Underground Space and Engineering;2010-06\n2 WANG Lei JIANG Jing-ping (College of Electrical Engineering,Zhejiang University,Hangzhou 310027,China);Brushless DC Motor Network Control Drive System Based on ARM and DSP[J];Journal of Beijing University of Technology;2008-03\n3 DU Xiu-li~1 LIAO Wei-zhang~2 TIAN Zhi-min~3 SHI Lei~1 1.College of Architecture and Civil Engineering,Beijing University of Technology,Beijing 100022,China; 2.Beijing Building Construction Research Institute,Beijing 100039,China; 3.The Beijing Canbao Institute of Architectural Design,Beijing 100850,China;State-of-the-art in the Dynamic Responses and Blast Resistant Measures of the Buildings Under Explosive Loads[J];Journal of Beijing University of Technology;2008-03\n5 WANG Guangyong①②,LI Guilin①,ZHANG Suhua①①School of Civil Engineering,He'nan Polytechnic University(He'nan Jiaozuo,454000)②Department of Modern Mechanics,University of Science and Technology of China(Anhui Hefei,230026);Numerical Analysis of the Anti-explosion Anchored Effects of Lined Tunnel under Dynamic Loads[J];Explosive Materials;2009-06\n6 WANG Youkai①②,WANG Hui②,WANG Guangyong②①Department of Modern Mechanics,University of Science and Technology of China(Anhui Hefei,230026)②School of Civil Engineering,He'nan Polytechnic University(He'nan Jiaozuo,454000);Research on the Influence of Radius on Dynamic Stress Concentration Factor and Vibration Acceleration of Underground Openings[J];Explosive Materials;2010-06\n7 ZHAO Bao-you1,2, MA Zhen-yue1, LIANG Bing2, XU Wei1,3, XU Xin-yong1(1. School of Civil and Hydraulic Engineering, Dalian University of Technology,Dalian 116085, Liaoning, China;2. College of Mechanics and Engineering Science, Liaoning Technical University, Fuxin 123000, Liaoning, China;3. Water Resources College, Shenyang Agricultural University,Shenyang 110161, Liaoning, China);Blast resistance of large underground rock caverns in hydraulic power stations[J];Explosion and Shock Waves;2010-02\n8 ZHAO Baoyou1,MA Zhenyue2(1.School of Mechanics and Engineering,Liaoning Technical University,Fuxin 123000,China;2.Faculty of Infrastructure Engineering,Dalian University of Technology,Dalian 116085,China);Feasibility study on seismic resistance of soft seismic absorption layer for large rock cavern[J];Journal of Earthquake Engineering and Engineering Vibration;2011-02\n9 WANG Guangyong,YU Yongqiang,ZHANG Suhua,LIU Xiliang (School of Civil Engineering,Henan Polytechnic University,Jiaozuo 454000,China);Distribution of dynamic stress concentration factor of underground openings[J];Journal of Liaoning Technical University(Natural Science);2010-04\n10 YANG Qiang,LIU Yao-ru,CHANG Qiang,LENG Kuang-dai,ZHOU Wei-yuan,YANG Ruo-qiong(State Key Laboratory of Hydroscience and Hydraulic Engineering,Tsinghua University,Beijing 100084,China);DEFORMATION STABILITY AND CONTROL THEORY OF STRUCTURES AND APPLICATION IN ROCK AND SOIL ENGINEERING[J];Engineering Mechanics;2010-S2\n2 SHEN Jun1,2,GU Jin-cai2,CHEN An-min2,XU Jing-mao2,MING Zhi-qing2,ZHANG Xiang-yang2(1.China University of Mining and Technology,Beijing 100083;2.The third engineer scientific research institute of the headquarters,the general staff,Luoyang 471023);Development and Applications of the Model Test Apparatus on Anti-explosion Structures in Geotechnical Engineering[J];Chinese Journal of Underground Space and Engineering;2007-06\n7 YU Xiang, CHEN Qi liang, ZHAO Yue tang, WANG Ming yang, GUO Sheng bing [WT5”BZ](Engineering Institute of Engineering Corps, PLAUST, Nanjing 210007, China);The Status Quo and Methods of Antiseismic Research of Underground Structure[J];Journal of PLA University of Science and Technology(Natural Science);2000-05\n8 HE Hu cheng 1, TANG De gao 1, CHEN Xiang xin 2, LI Shui quan 1 (1. Engineering Institute of Engineering Corps, PLA Univ. of Sci. & Tech., Nanjing 210007, China; 2. Engineering Design & Research Institute of Strategic Missile Corps, PLA, Beijing 100011, China);Study on Flexural Resistance of Component Strengthened by Carbon Fiber Reinforced Plastics under Explosive Blast[J];Journal of PLA University of Science and Technology(Natural Science);2002-06\n9 Gai Bing-zheng (Harbin Institute of Technology);ON THE DIFFRACTION OF ELASTIC WAVE AND DYNAMIC STRESS CONCENTRATION[J];Advances In Mechanics;1987-04\n10 Liu Diankui Liu Hongwei (Dept of Civil Engineering, Harbin Engineering University, Harbin 150001, China) 1) The project supported by the National Natural Science Foundation of China and the State Education Commission of China;SCATTERING AND DYNAMIC STRESS CONCENTRATION OF SH-WAVE BY INTERFACE CIRCULAR HOLE 1)[J];ACTA MECHANICA SINICA;1998-05


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