ISMARA results: Creb3\nMotif ID: Creb3\nTranscription factors associated with Creb3:\nCreb3 ENSMUSG00000028466.9 Creb3\nCreb3 mm10_v2_chr4_+_43562672_43562947 0.17 3.4e-01 Click!\nActivity profile for motif Creb3.\nSorted Z-values histogram for motif Creb3\nFirst level regulatory network of Creb3\nchr3_+_123267445 7.667 ENSMUST00000047923.7\nchr17_+_35439155 7.243 ENSMUST00000071951.6\nchr1_+_58113136 6.784 ENSMUST00000040999.7\nchr16_+_13903152 5.399 ENSMUST00000128757.1\nchr4_-_105109829 5.195 ENSMUST00000030243.7\nchr8_+_107150621 5.116 ENSMUST00000034400.3\nchr9_+_44379490 5.071 ENSMUST00000066601.6\nchr14_-_59597836 4.871 ENSMUST00000167100.1\nchr2_+_67748212 4.766 ENSMUST00000180887.1\nchr9_+_44379536 4.690 ENSMUST00000161318.1\nchr9_-_45009590 4.666 ENSMUST00000102832.1\nchr2_+_105224314 4.627 ENSMUST00000068813.2\nchr10_-_24101951 4.188 ENSMUST00000170267.1\nchr17_-_26508463 4.099 ENSMUST00000025025.6\nchr3_+_122895072 4.078 ENSMUST00000023820.5\nchr2_+_72054598 4.012 ENSMUST00000028525.5\nchr3_+_89459325 3.755 ENSMUST00000107410.1\nchr17_-_57228003 3.727 ENSMUST00000177046.1\nchr4_-_118544010 3.576 ENSMUST00000128098.1\nchr10_-_4432312 3.452 ENSMUST00000126102.1\nchr10_+_41519493 3.432 ENSMUST00000019962.8\nchr2_+_155276297 3.405 ENSMUST00000029128.3\nchr8_-_106136890 3.286 ENSMUST00000115979.2\nchr2_-_168742100 3.265 ENSMUST00000109177.1\nchr1_-_183369529 3.185 ENSMUST00000069922.5\nchr8_-_106136792 3.169 ENSMUST00000146940.1\nchr5_+_28071356 3.101 ENSMUST00000059155.10\nchr2_+_173153048 3.073 ENSMUST00000029017.5\nchr7_+_27195781 2.970 ENSMUST00000108379.1\nchrX_+_73787062 2.965 ENSMUST00000002090.2\nchrX_+_73787002 2.921 ENSMUST00000166518.1\nchr7_-_126898249 2.912 ENSMUST00000121532.1\nchr9_+_104063376 2.912 ENSMUST00000120854.1\nchr11_-_72796028 2.896 ENSMUST00000156294.1\nchr10_-_4432285 2.838 ENSMUST00000155172.1\nchr11_-_72795801 2.818 ENSMUST00000079681.5\nchr5_+_125389284 2.813 ENSMUST00000100700.2\nchr11_+_52232183 2.716 ENSMUST00000109072.1\nchr19_-_10101501 2.664 ENSMUST00000025567.7\nchr7_+_128523576 2.544 ENSMUST00000033136.7\nchr10_-_81407641 2.518 ENSMUST00000140916.1\nchr13_-_37994111 2.500 ENSMUST00000021864.6\nchr7_-_44496406 2.431 ENSMUST00000118515.1\nchr3_+_155093414 2.377 ENSMUST00000029833.7\nchr5_+_107331157 2.311 ENSMUST00000031215.8\nchr10_-_67285180 2.293 ENSMUST00000159002.1\nchr11_+_52232009 2.285 ENSMUST00000037324.5\nchr3_+_89459118 2.223 ENSMUST00000029564.5\nchrX_-_136741155 2.218 ENSMUST00000166930.1\nchr15_-_3995708 2.216 ENSMUST00000046633.8\nchrX_-_60893430 2.197 ENSMUST00000135107.2\nchr2_-_148040196 2.154 ENSMUST00000136555.1\nchr19_-_6909599 2.150 ENSMUST00000173091.1\nchr1_+_131019843 2.126 ENSMUST00000016673.5\nchr3_+_88206786 2.109 ENSMUST00000181134.1\npredicted gene 3764\nchr11_-_69920581 2.077 ENSMUST00000108610.1\nchr4_+_153957230 2.053 ENSMUST00000058393.2\nchr14_-_55643523 2.053 ENSMUST00000132338.1\nchr1_+_157506728 2.053 ENSMUST00000086130.2\nchr1_+_157506777 2.047 ENSMUST00000027881.8\nchr5_+_91139591 2.017 ENSMUST00000031325.4\nchr14_-_55643800 1.987 ENSMUST00000122358.1\nchr17_-_90088343 1.967 ENSMUST00000173917.1\nchr4_+_153957247 1.966 ENSMUST00000141493.1\nchr9_-_104063049 1.957 ENSMUST00000035166.5\nchr6_-_119848120 1.953 ENSMUST00000183703.1\nchr10_+_128322443 1.952 ENSMUST00000026446.2\nchr7_-_45459839 1.949 ENSMUST00000094434.4\nchr8_+_108714644 1.938 ENSMUST00000043896.8\nchr8_-_34146974 1.916 ENSMUST00000033910.8\nchr6_+_48593883 1.915 ENSMUST00000154010.1\nchr6_+_88084473 1.911 ENSMUST00000032143.6\nchr11_-_86807624 1.883 ENSMUST00000018569.7\nchr6_-_119848059 1.860 ENSMUST00000184864.1\nchr11_-_88863717 1.845 ENSMUST00000107904.2\nchr9_+_67759423 1.817 ENSMUST00000171652.1\nchr14_-_55643720 1.813 ENSMUST00000138085.1\nchr17_-_34214459 1.795 ENSMUST00000121995.1\nchr7_-_90475971 1.791 ENSMUST00000032843.7\nchr7_+_44496588 1.785 ENSMUST00000107927.3\nchr17_+_46383725 1.775 ENSMUST00000113481.1\nchr1_+_171345684 1.774 ENSMUST00000006579.4\nchr11_+_94653767 1.773 ENSMUST00000025278.7\nchr2_+_162987502 1.766 ENSMUST00000117123.1\nchr7_-_133776681 1.761 ENSMUST00000130182.1\nchr3_+_30792876 1.759 ENSMUST00000029256.7\nchr9_+_108339048 1.755 ENSMUST00000082429.5\nchr19_-_6910088 1.741 ENSMUST00000025904.5\nchr9_+_44084944 1.741 ENSMUST00000176416.1\nchr17_-_56183887 1.739 ENSMUST00000019723.7\nchr8_+_111033890 1.730 ENSMUST00000034441.7\nchr12_+_51377560 1.723 ENSMUST00000021335.5\nchr15_+_99591028 1.689 ENSMUST00000169082.1\nchr6_-_108185552 1.649 ENSMUST00000167338.1\nchr7_+_102210335 1.637 ENSMUST00000140631.1\nchr2_+_155382186 1.631 ENSMUST00000134218.1\nchr6_-_71144338 1.630 ENSMUST00000074241.7\nchr4_+_47474652 1.598 ENSMUST00000065678.5\nchr13_-_38528412 1.597 ENSMUST00000035988.8\nchr5_+_107403496 1.578 ENSMUST00000049146.5\nchr5_+_124540695 1.553 ENSMUST00000060226.4\nchr9_+_44101722 1.552 ENSMUST00000161703.1\nchr3_-_155093346 1.548 ENSMUST00000066568.4\nchr7_-_144939823 1.548 ENSMUST00000093962.4\nchr4_+_3938888 1.543 ENSMUST00000121110.1\nchr2_+_80315461 1.534 ENSMUST00000028392.7\nchr5_+_113735782 1.520 ENSMUST00000065698.5\nchr4_+_108328136 1.508 ENSMUST00000131656.1\nchr17_+_6106880 1.492 ENSMUST00000149756.1\nchr12_-_59011996 1.483 ENSMUST00000021375.5\nchr19_-_6057736 1.481 ENSMUST00000007482.6\nchr12_+_69184158 1.477 ENSMUST00000060579.8\nchr13_-_100833369 1.476 ENSMUST00000067246.4\nchr19_+_11965817 1.467 ENSMUST00000025590.9\nchr5_+_120431770 1.460 ENSMUST00000031591.7\nchr10_-_115251407 1.449 ENSMUST00000020339.8\nchr19_+_8741669 1.439 ENSMUST00000176314.1\nchr7_+_127912510 1.423 ENSMUST00000033070.7\nchrX_-_155623325 1.408 ENSMUST00000038665.5\nchrX_+_99821021 1.403 ENSMUST00000096363.2\nchr3_+_89246397 1.394 ENSMUST00000168900.1\nchr7_-_16874845 1.394 ENSMUST00000181501.1\nRIKEN cDNA 9330104G04 gene\nchr6_-_119848093 1.392 ENSMUST00000079582.4\nchr4_+_33031371 1.384 ENSMUST00000124992.1\nchr12_+_108792946 1.383 ENSMUST00000021692.7\nchr10_-_128923948 1.381 ENSMUST00000131271.1\nchr4_-_150909812 1.375 ENSMUST00000134751.1\nchr7_+_45873127 1.374 ENSMUST00000107718.1\nchr7_-_118533298 1.366 ENSMUST00000098090.3\nchr8_+_45975514 1.358 ENSMUST00000034051.6\nchr5_-_124352233 1.358 ENSMUST00000111472.1\nchr14_+_26638237 1.346 ENSMUST00000112318.3\nchr9_+_59539643 1.343 ENSMUST00000026262.6\nchr11_-_51756378 1.339 ENSMUST00000109092.1\nchr16_-_13903085 1.335 ENSMUST00000023361.5\nchr4_+_59003121 1.331 ENSMUST00000095070.3\nchrX_-_163549677 1.330 ENSMUST00000033730.2\nchr14_+_69555377 1.330 ENSMUST00000185072.1\npredicted gene, 21685\nchr2_-_132247623 1.326 ENSMUST00000110164.1\nchr11_+_82781108 1.308 ENSMUST00000092849.5\nchr14_-_55643251 1.286 ENSMUST00000120041.1\nchr8_+_92961027 1.283 ENSMUST00000072939.6\nchr4_-_148038769 1.274 ENSMUST00000030879.5\nchr10_+_24076500 1.274 ENSMUST00000051133.5\nchr10_-_128922888 1.269 ENSMUST00000135161.1\nchr2_-_132247747 1.258 ENSMUST00000110163.1\nchr1_-_93445642 1.246 ENSMUST00000042498.7\nchr1_-_172082757 1.239 ENSMUST00000003550.4\nchr18_-_35215008 1.219 ENSMUST00000091636.3\nchr10_-_128923439 1.205 ENSMUST00000153731.1\nchr16_-_44139196 1.204 ENSMUST00000063661.6\nchr10_+_121365078 1.173 ENSMUST00000040344.6\nchr5_-_31291026 1.163 ENSMUST00000041565.7\nchr1_+_75168631 1.157 ENSMUST00000162768.1\nchr19_+_8741473 1.156 ENSMUST00000177373.1\nchr2_-_91070283 1.146 ENSMUST00000111436.2\nchr2_+_70661556 1.125 ENSMUST00000112201.1\nchr19_+_8741413 1.124 ENSMUST00000176381.1\nchr16_+_36875119 1.121 ENSMUST00000135406.1\nchr1_-_13589717 1.120 ENSMUST00000027068.4\nchr13_-_55321928 1.119 ENSMUST00000035242.7\nchr17_-_24163668 1.119 ENSMUST00000040735.5\nchr11_-_118415794 1.117 ENSMUST00000164927.1\nchr18_-_84685615 1.116 ENSMUST00000025546.9\nchr3_-_97767916 1.115 ENSMUST00000045243.8\nchrX_-_20291776 1.106 ENSMUST00000072451.4\nchr6_-_134897815 1.104 ENSMUST00000165392.1\nchr11_+_72796164 1.092 ENSMUST00000172220.1\nchr10_+_79682169 1.074 ENSMUST00000020550.5\nchr16_-_13903051 1.072 ENSMUST00000115803.1\nchr6_-_101377342 1.063 ENSMUST00000151175.1\nchr11_+_72796254 1.061 ENSMUST00000069395.5\nchr9_-_20976762 1.057 ENSMUST00000054197.5\nchr12_-_4038905 1.056 ENSMUST00000111178.1\nchr19_-_5802640 1.055 ENSMUST00000173523.1\nchr6_+_29348069 1.036 ENSMUST00000173216.1\nchr5_+_143403819 1.034 ENSMUST00000110731.2\nchr16_-_13903015 1.031 ENSMUST00000115804.2\nchr17_-_47688028 1.029 ENSMUST00000113301.1\nchr2_+_23156369 1.024 ENSMUST00000028117.3\nchr15_-_99820072 1.016 ENSMUST00000109024.2\nchr1_-_51478390 1.008 ENSMUST00000027279.5\nchr1_+_182124737 0.992 ENSMUST00000111018.1\nchr13_+_55321991 0.979 ENSMUST00000021942.6\nchr1_+_75142775 0.978 ENSMUST00000097694.4\nchr14_+_79587691 0.968 ENSMUST00000054908.8\nchr5_-_143732273 0.968 ENSMUST00000053287.5\nchr15_-_102136225 0.964 ENSMUST00000154032.1\nchr2_+_74762980 0.949 ENSMUST00000047793.4\nchr14_-_31251194 0.935 ENSMUST00000022459.3\nchr5_+_30869623 0.929 ENSMUST00000114716.1\nchr4_+_3938904 0.926 ENSMUST00000120732.1\nchr2_-_91070180 0.918 ENSMUST00000153367.1\nchr5_+_30869579 0.917 ENSMUST00000046349.7\nchr11_+_53350783 0.912 ENSMUST00000060945.5\nchr10_+_77606571 0.911 ENSMUST00000099538.5\nchr4_-_134000857 0.909 ENSMUST00000105887.1\nchr12_+_71309876 0.897 ENSMUST00000061273.5\nchr10_+_127041931 0.896 ENSMUST00000006915.7\nchr17_-_34121944 0.895 ENSMUST00000151986.1\n3.3 9.8 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)\n1.5 6.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)\n1.4 6.8 GO:0009115 xanthine catabolic process(GO:0009115)\n1.3 3.9 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)\n1.2 17.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)\n1.0 4.0 GO:1904457 positive regulation of neuronal action potential(GO:1904457)\n0.9 4.7 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)\n0.9 5.4 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)\n0.7 3.7 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)\n0.7 2.1 GO:0060300 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) regulation of cytokine activity(GO:0060300) negative regulation of sensory perception of pain(GO:1904057)\n0.6 1.9 GO:1904059 regulation of locomotor rhythm(GO:1904059)\n0.6 3.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)\n0.6 1.7 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)\n0.5 4.8 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)\n0.5 2.0 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)\n0.5 2.0 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)\n0.5 1.9 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)\n0.5 6.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)\n0.5 4.7 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)\n0.5 1.4 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)\n0.5 1.4 GO:1903184 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) protein deglycation(GO:0036525) peptidyl-cysteine deglycation(GO:0036526) peptidyl-arginine deglycation(GO:0036527) peptidyl-lysine deglycation(GO:0036528) protein deglycation, glyoxal removal(GO:0036529) glutathione deglycation(GO:0036531) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)\n0.4 3.7 GO:0090166 Golgi disassembly(GO:0090166)\n0.4 1.6 GO:0006566 threonine metabolic process(GO:0006566)\n0.4 2.0 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)\n0.4 5.2 GO:0014850 response to muscle activity(GO:0014850)\n0.4 4.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)\n0.3 2.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)\n0.3 1.4 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)\n0.3 1.3 GO:0036343 psychomotor behavior(GO:0036343)\n0.3 1.3 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298)\n0.3 2.0 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)\n0.3 1.0 GO:0052203 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)\n0.3 1.9 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)\n0.3 1.5 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)\n0.3 1.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)\n0.3 2.6 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)\n0.3 1.8 GO:0018158 protein oxidation(GO:0018158)\n0.2 1.0 GO:1901857 positive regulation of cellular respiration(GO:1901857)\n0.2 0.7 GO:0070625 zymogen granule exocytosis(GO:0070625)\n0.2 1.8 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)\n0.2 2.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)\n0.2 1.1 GO:0035063 nuclear speck organization(GO:0035063)\n0.2 0.4 GO:0070375 ERK5 cascade(GO:0070375)\n0.2 8.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)\n0.2 0.8 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)\n0.2 1.7 GO:0015670 carbon dioxide transport(GO:0015670)\n0.2 5.0 GO:0035518 histone H2A monoubiquitination(GO:0035518)\n0.2 1.5 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)\n0.2 0.5 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)\n0.2 1.3 GO:0006689 ganglioside catabolic process(GO:0006689)\n0.2 4.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)\n0.2 1.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262) glucosamine-containing compound catabolic process(GO:1901072)\n0.2 6.5 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)\n0.2 1.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)\n0.2 7.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)\n0.1 1.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)\n0.1 0.8 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)\n0.1 2.1 GO:0061525 hindgut development(GO:0061525)\n0.1 2.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)\n0.1 1.8 GO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane(GO:0006620)\n0.1 0.5 GO:0097476 spinal cord motor neuron migration(GO:0097476)\n0.1 1.6 GO:0098719 sodium ion import across plasma membrane(GO:0098719)\n0.1 1.5 GO:0006824 cobalt ion transport(GO:0006824)\n0.1 1.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)\n0.1 2.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)\n0.1 1.6 GO:0032525 somite rostral/caudal axis specification(GO:0032525)\n0.1 2.3 GO:0007141 male meiosis I(GO:0007141)\n0.1 4.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)\n0.1 4.1 GO:0050892 intestinal absorption(GO:0050892)\n0.1 1.7 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)\n0.1 1.1 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)\n0.1 0.9 GO:0016093 polyprenol metabolic process(GO:0016093)\n0.1 1.2 GO:0007220 Notch receptor processing(GO:0007220)\n0.1 1.9 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)\n0.1 1.0 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)\n0.1 1.0 GO:0036296 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296)\n0.1 0.3 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)\n0.1 2.3 GO:0000188 inactivation of MAPK activity(GO:0000188)\n0.1 1.4 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cytosol(GO:1902656)\n0.1 1.1 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)\n0.1 1.5 GO:0044126 regulation of growth of symbiont in host(GO:0044126)\n0.1 2.2 GO:0060009 Sertoli cell development(GO:0060009)\n0.1 0.7 GO:0045794 negative regulation of cell volume(GO:0045794)\n0.1 1.0 GO:0051382 kinetochore assembly(GO:0051382)\n0.1 1.4 GO:0021794 thalamus development(GO:0021794)\n0.1 0.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)\n0.1 1.6 GO:0043277 apoptotic cell clearance(GO:0043277)\n0.1 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)\n0.1 0.7 GO:0034982 mitochondrial protein processing(GO:0034982)\n0.1 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)\n0.1 0.6 GO:0010668 ectodermal cell differentiation(GO:0010668)\n0.1 1.6 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)\n0.1 0.4 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)\n0.1 1.4 GO:0002091 negative regulation of receptor internalization(GO:0002091)\n0.1 3.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)\n0.0 0.9 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)\n0.0 1.4 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)\n0.0 0.6 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)\n0.0 1.4 GO:0002369 T cell cytokine production(GO:0002369)\n0.0 2.3 GO:0043550 regulation of lipid kinase activity(GO:0043550)\n0.0 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)\n0.0 0.9 GO:0009311 oligosaccharide metabolic process(GO:0009311)\n0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)\n0.0 1.6 GO:0042462 eye photoreceptor cell development(GO:0042462)\n0.0 1.4 GO:0060325 face morphogenesis(GO:0060325)\n0.0 1.3 GO:1903959 regulation of anion transmembrane transport(GO:1903959)\n0.0 1.1 GO:0007528 neuromuscular junction development(GO:0007528)\n0.0 1.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)\n0.0 2.5 GO:0090630 activation of GTPase activity(GO:0090630)\n0.0 0.5 GO:0060324 face development(GO:0060324)\n0.0 1.6 GO:0010508 positive regulation of autophagy(GO:0010508)\n0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)\n0.0 1.0 GO:0031529 ruffle organization(GO:0031529)\n0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)\n0.0 0.7 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)\n0.0 2.5 GO:0048489 synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480) vesicle-mediated transport in synapse(GO:0099003)\n0.0 0.7 GO:0008333 endosome to lysosome transport(GO:0008333)\n0.0 0.1 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)\n0.0 0.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)\n0.0 1.8 GO:0032411 positive regulation of transporter activity(GO:0032411)\n0.0 1.3 GO:0006457 protein folding(GO:0006457)\n0.0 1.1 GO:0007030 Golgi organization(GO:0007030)\n0.0 2.9 GO:0006914 autophagy(GO:0006914) process utilizing autophagic mechanism(GO:0061919)\n0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)\n0.0 1.2 GO:0030203 glycosaminoglycan metabolic process(GO:0030203)\n0.0 0.8 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)\n0.0 1.2 GO:0008203 cholesterol metabolic process(GO:0008203)\n0.8 11.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)\n0.8 4.0 GO:0044316 cone cell pedicle(GO:0044316)\n0.8 11.5 GO:0030127 COPII vesicle coat(GO:0030127)\n0.7 7.5 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)\n0.7 5.0 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)\n0.6 7.2 GO:0042612 MHC class I protein complex(GO:0042612)\n0.5 4.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)\n0.4 3.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)\n0.4 5.4 GO:0044754 autolysosome(GO:0044754)\n0.4 2.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)\n0.4 2.6 GO:0099078 BORC complex(GO:0099078)\n0.3 5.2 GO:0008385 IkappaB kinase complex(GO:0008385)\n0.3 2.5 GO:0097413 Lewy body(GO:0097413)\n0.3 1.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)\n0.3 1.4 GO:0072487 MSL complex(GO:0072487)\n0.2 1.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)\n0.2 3.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)\n0.2 1.0 GO:0070876 SOSS complex(GO:0070876)\n0.2 2.1 GO:0005642 annulate lamellae(GO:0005642)\n0.2 3.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)\n0.2 0.7 GO:0005745 m-AAA complex(GO:0005745)\n0.2 0.9 GO:0043527 tRNA methyltransferase complex(GO:0043527)\n0.2 1.8 GO:0016272 prefoldin complex(GO:0016272)\n0.2 2.4 GO:0072546 ER membrane protein complex(GO:0072546)\n0.2 5.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)\n0.2 1.7 GO:0030126 COPI vesicle coat(GO:0030126)\n0.2 1.2 GO:0070765 gamma-secretase complex(GO:0070765)\n0.1 3.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)\n0.1 0.7 GO:0034715 pICln-Sm protein complex(GO:0034715)\n0.1 1.0 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)\n0.1 0.7 GO:0005796 Golgi lumen(GO:0005796)\n0.1 1.8 GO:0030061 mitochondrial crista(GO:0030061)\n0.1 1.7 GO:0017119 Golgi transport complex(GO:0017119)\n0.1 1.6 GO:0042589 zymogen granule membrane(GO:0042589)\n0.1 1.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)\n0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)\n0.1 2.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189)\n0.1 1.3 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)\n0.1 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)\n0.1 1.4 GO:0031011 Ino80 complex(GO:0031011)\n0.1 1.1 GO:0005797 Golgi medial cisterna(GO:0005797)\n0.1 3.5 GO:0005801 cis-Golgi network(GO:0005801)\n0.1 3.7 GO:0031201 SNARE complex(GO:0031201)\n0.1 14.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)\n0.1 0.5 GO:0036501 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) UFD1-NPL4 complex(GO:0036501)\n0.1 3.6 GO:0005776 autophagosome(GO:0005776)\n0.1 7.5 GO:0055037 recycling endosome(GO:0055037)\n0.1 0.2 GO:0032783 ELL-EAF complex(GO:0032783)\n0.0 1.5 GO:0005795 Golgi stack(GO:0005795)\n0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)\n0.0 10.5 GO:0000139 Golgi membrane(GO:0000139)\n0.0 2.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)\n0.0 1.8 GO:0005881 cytoplasmic microtubule(GO:0005881)\n0.0 3.1 GO:0072562 blood microparticle(GO:0072562)\n0.0 1.7 GO:0009925 basal plasma membrane(GO:0009925)\n0.0 1.4 GO:0060076 excitatory synapse(GO:0060076)\n0.0 1.3 GO:0099086 synaptonemal complex(GO:0000795) synaptonemal structure(GO:0099086)\n0.0 7.0 GO:0005743 mitochondrial inner membrane(GO:0005743)\n0.0 2.7 GO:0001650 fibrillar center(GO:0001650)\n0.0 2.5 GO:0030018 Z disc(GO:0030018)\n0.0 6.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)\n0.0 0.5 GO:0045335 phagocytic vesicle(GO:0045335)\n0.0 1.5 GO:0005923 bicellular tight junction(GO:0005923)\n0.0 1.0 GO:0005913 cell-cell adherens junction(GO:0005913)\n0.0 0.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)\n1.4 4.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)\n1.4 6.8 GO:0016623 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)\n1.3 3.9 GO:0072541 peroxynitrite reductase activity(GO:0072541)\n1.2 4.8 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)\n1.1 3.2 GO:0042954 lipoprotein transporter activity(GO:0042954)\n1.0 2.9 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)\n0.6 4.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)\n0.6 1.7 GO:0004813 alanine-tRNA ligase activity(GO:0004813)\n0.6 7.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)\n0.5 1.6 GO:0070905 serine binding(GO:0070905)\n0.5 2.7 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)\n0.5 1.4 GO:0036478 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) protein deglycase activity(GO:0036524)\n0.4 2.0 GO:0097109 neuroligin family protein binding(GO:0097109)\n0.3 1.0 GO:1990050 phosphatidic acid transporter activity(GO:1990050)\n0.3 3.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)\n0.3 5.2 GO:0035174 histone serine kinase activity(GO:0035174)\n0.3 2.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)\n0.3 1.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)\n0.3 1.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)\n0.2 3.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)\n0.2 1.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)\n0.2 1.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)\n0.2 1.5 GO:0070568 guanylyltransferase activity(GO:0070568)\n0.2 5.0 GO:0097602 cullin family protein binding(GO:0097602)\n0.2 1.2 GO:0005047 signal recognition particle binding(GO:0005047)\n0.2 4.0 GO:0070577 lysine-acetylated histone binding(GO:0070577) acetylation-dependent protein binding(GO:0140033)\n0.2 1.4 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)\n0.2 9.1 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)\n0.1 1.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)\n0.1 1.8 GO:0030346 protein phosphatase 2B binding(GO:0030346)\n0.1 2.1 GO:0017070 U6 snRNA binding(GO:0017070)\n0.1 1.7 GO:0015250 water channel activity(GO:0015250)\n0.1 5.1 GO:0005484 SNAP receptor activity(GO:0005484)\n0.1 3.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)\n0.1 1.8 GO:0017081 chloride channel regulator activity(GO:0017081)\n0.1 4.0 GO:0030552 cAMP binding(GO:0030552)\n0.1 10.8 GO:0020037 heme binding(GO:0020037)\n0.1 1.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)\n0.1 1.2 GO:0042043 neurexin family protein binding(GO:0042043)\n0.1 3.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)\n0.1 3.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)\n0.1 0.8 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding(GO:0070530)\n0.1 1.5 GO:0051787 misfolded protein binding(GO:0051787)\n0.1 1.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)\n0.1 1.1 GO:0016805 dipeptidase activity(GO:0016805)\n0.1 2.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)\n0.1 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)\n0.1 6.2 GO:0000149 SNARE binding(GO:0000149)\n0.1 0.9 GO:0050811 GABA receptor binding(GO:0050811)\n0.1 1.8 GO:0044183 protein binding involved in protein folding(GO:0044183)\n0.0 1.5 GO:0015248 sterol transporter activity(GO:0015248)\n0.0 1.0 GO:0017049 GTP-Rho binding(GO:0017049)\n0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)\n0.0 3.5 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)\n0.0 5.2 GO:0030165 PDZ domain binding(GO:0030165)\n0.0 1.5 GO:0070566 adenylyltransferase activity(GO:0070566)\n0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)\n0.0 1.3 GO:0008188 neuropeptide receptor activity(GO:0008188)\n0.0 1.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)\n0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)\n0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)\n0.0 3.4 GO:0008565 protein transporter activity(GO:0008565)\n0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)\n0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)\n0.0 1.4 GO:0016790 thiolester hydrolase activity(GO:0016790)\n0.0 0.8 GO:0008378 galactosyltransferase activity(GO:0008378)\n0.0 0.3 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)\n0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)\n0.0 1.1 GO:0019213 deacetylase activity(GO:0019213)\n0.0 2.1 GO:0070851 growth factor receptor binding(GO:0070851)\n0.0 3.7 GO:0008641 small protein activating enzyme activity(GO:0008641)\n0.0 1.9 GO:0005506 iron ion binding(GO:0005506)\n0.0 3.7 GO:0004866 endopeptidase inhibitor activity(GO:0004866)\n0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)\n0.0 1.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)\n0.0 1.8 GO:0042826 histone deacetylase binding(GO:0042826)\n0.0 1.4 GO:0004497 monooxygenase activity(GO:0004497)\n0.0 1.9 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)\n0.2 3.7 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network\n0.1 4.2 PID_ARF_3PATHWAY Arf1 pathway\n0.1 6.0 PID_IL1_PATHWAY IL1-mediated signaling events\n0.1 4.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4\n0.1 2.0 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network\n0.1 4.1 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta\n0.1 1.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events\n0.1 5.5 PID_LKB1_PATHWAY LKB1 signaling events\n0.1 1.7 PID_RB_1PATHWAY Regulation of retinoblastoma protein\n0.0 2.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network\n0.0 1.3 PID_CONE_PATHWAY Visual signal transduction: Cones\n0.0 2.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction\n0.0 1.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling\n0.0 2.1 PID_AP1_PATHWAY AP-1 transcription factor network\n0.0 1.2 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins\n0.0 1.0 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway\n0.5 4.7 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse\n0.3 5.2 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK\n0.3 3.7 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade\n0.2 3.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism\n0.2 2.5 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation\n0.2 2.0 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases\n0.2 11.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)\n0.2 1.8 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism\n0.2 1.7 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport\n0.1 1.7 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins\n0.1 2.7 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism\n0.1 4.2 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis\n0.1 4.0 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling\n0.1 1.3 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway\n0.1 2.1 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation\n0.1 0.9 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle\n0.1 1.2 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR\n0.1 9.9 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane\n0.1 1.6 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi\n0.1 3.3 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases\n0.1 1.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters\n0.1 1.1 REACTOME_TRNA_AMINOACYLATION Genes involved in tRNA Aminoacylation\n0.1 1.8 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC\n0.0 1.1 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism\n0.0 1.5 REACTOME_G1_PHASE Genes involved in G1 Phase\n0.0 0.4 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing\n0.0 3.9 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation


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