Baltimore is the largest city in the U.S. state of Maryland, and the 29th-most populous city in the country. 

Baltimore was established by the Constitution of Maryland and is not part of any county. With a population of 621,849 in 2015, Baltimore is the largest independent city in the United States. As of 2016, the population of the Baltimore metropolitan area was estimated to be just under 2.8 million, making it the 21st largest metropolitan area in the country. Baltimore is also part of the Washington-Baltimore combined statistical area (CSA), the fourth largest CSA in the nation with a calculated 2016 population of 9,665,892. 

Founded in 1729, Baltimore is the second-largest seaport in the Mid-Atlantic. The city's Inner Harbor was once the second leading port of entry for immigrants to the United States and a major manufacturing center. After a decline in major manufacturing, industrialization, and rail transportation, Baltimore shifted to a service-oriented economy, with Johns Hopkins Hospital (founded 1889) and Johns Hopkins University (founded 1876), now the city's top two employers. 

With hundreds of identified districts, Baltimore has been dubbed a "city of neighborhoods." Famous residents have included writers Edgar Allan Poe, Edith Hamilton, Frederick Douglass, and H.L. Mencken; jazz musician James "Eubie" Blake; singer Billie Holiday; actor and filmmaker John Waters; and baseball player Babe Ruth. In the War of 1812, Francis Scott Key wrote "The Star-Spangled Banner", which later became the American national anthem, in Baltimore.
what's the largest city in maryland?
what's the population
Is it the 2nd largest seaport?
What's the city's top employers?
Anyone famous hail from here?
What was he?
what about musicians?
what kind of music did he do?
was it ever a leading port for immigrants?
In what areas did it decline?
What was so special about 1812?
and that was in Balitmore?
Baltimore
Baltimore is the largest city in the U.S. state of Maryland
just under 2.8 million
 the population of the Baltimore metropolitan area was estimated to be just under 2.8 million
yes
Founded in 1729, Baltimore is the second-largest seaport in the Mid-Atlantic
Johns Hopkins Hospital and Johns Hopkins University
Johns Hopkins Hospital (founded 1889) and Johns Hopkins University (founded 1876), now the city's top two employers. 
Edgar Allan Poe
 Famous residents have included writers Edgar Allan Poe
a writer
 writers Edgar Allan Poe
James "Eubie" Blake
 jazz musician James "Eubie" Blake
jazz
 jazz musician James "Eubie"
yes
he city's Inner Harbor was once the second leading port of entry for immigrants
in major manufacturing, industrialization, and rail transportation
After a decline in major manufacturing, industrialization, and rail transportation, 
Francis Scott Key wrote "The Star-Spangled Banner"
In the War of 1812, Francis Scott Key wrote "The Star-Spangled Banner",
yes
which later became the American national anthem, in Baltimore.