With an estimated population of 1,381,069 as of July 1, 2014, San Diego is the eighth-largest city in the United States and second-largest in California. It is part of the San Diego–Tijuana conurbation, the second-largest transborder agglomeration between the US and a bordering country after Detroit–Windsor, with a population of 4,922,723 people. San Diego is the birthplace of California and is known for its mild year-round climate, natural deep-water harbor, extensive beaches, long association with the United States Navy and recent emergence as a healthcare and biotechnology development center. 

Historically home to the Kumeyaay people, San Diego was the first site visited by Europeans on what is now the West Coast of the United States. Upon landing in San Diego Bay in 1542, Juan Rodríguez Cabrillo claimed the entire area for Spain, forming the basis for the settlement of Alta California 200 years later. The Presidio and Mission San Diego de Alcalá, founded in 1769, formed the first European settlement in what is now California. In 1821, San Diego became part of the newly-independent Mexico, which reformed as the First Mexican Republic two years later. In 1850, it became part of the United States following the Mexican–American War and the admission of California to the union.
When did San Diego become part of the United States?
What group of people is it historically a home to?
Is it the largest city in the United States?
What is the population?
Who claimed the by for Spain?
What year was that?
What happened in 1821?
What is the weather there?
Are there beaches?
What military branch is based there?
Is became part of the US after what war?
Is it the largest city in California?
It is called the "what" of California?
What else it is known for?
What is it part of?
What is that?
Who is first largest?
When Juan Cabrillo claimed it, what basis did it form?
How many years later?
What did independent Mexico reform into?
1850
In 1850, it became part of the United States
Kumeyaay people
 the Kumeyaay people
No
San Diego is the eighth-largest city in the United States
1,381,069
With an estimated population of 1,381,069
uan Rodríguez Cabrillo
uan Rodríguez Cabrillo claimed the entire area for Spain,
1542
1542
It became part of the newly-independent Mexico
In 1821, San Diego became part of the newly-independent Mexico
mild year-round climate,
 is known for its mild year-round climate,
Yes
 extensive beaches
United States Navy
 United States Navy 
Mexican–American War
 it became part of the United States following the Mexican–American War
no
 second-largest in California
birthplace
San Diego is the birthplace of California
recent emergence as a healthcare and biotechnology development center.
recent emergence as a healthcare and biotechnology development center. 
San Diego–Tijuana conurbation
It is part of the San Diego–Tijuana conurbation
agglomeration between the US and a bordering country
 the second-largest transborder agglomeration between the US and a bordering country 
Detroit–Windsor
after Detroit–Windsor,
the settlement of Alta California
forming the basis for the settlement of Alta California 200 years later
200
200 years later.
First Mexican Republic
which reformed as the First Mexican Republic 