Actor Philip Seymour Hoffman, who was found dead February 2 on the bathroom floor of his New York apartment with a syringe in his left arm, died of acute mixed drug intoxication, including heroin, cocaine, benzodiazepines and amphetamine, the New York medical examiner's office said Friday. 

The manner of death was ruled an accident, the medical examiner's office said in a statement. 

Dr. Sanjay Gupta, CNN's chief medical correspondent, said that as addicts take mixtures of drugs more chronically, they may not necessarily feel the effects of the narcotics, which still suppress the respiratory system. 

"They're not feeling it, but it's still having an impact on their ability to breathe, and that's the real problem," he said. "It's called stacking. You can stack the same drug too close together, or you can start to stack other drugs, one on top of the other. That's how people get into trouble. They do call it accidental death as well." 

Police found nearly 50 envelopes branded "Ace of Spades" filled with what they believe was heroin in the actor's Manhattan apartment, two law enforcement sources familiar with the inquiry said. 

Used syringes, prescription drugs and empty bags that authorities suspect were used to hold heroin also were found in the apartment where Hoffman, 46, was found dead, sources said. 

He was expected to pick up his children that day but didn't show up, the official said. Playwright David Katz and another person went to the apartment and found him dead, the official said. 

Police officers found him in a T-shirt and shorts with his eyeglasses still on his head. 
What state medical examiner's office handled the actor's death?
What is the actor's first name?
And last name?
And middle name?
Was the actor's death judged to be an accident?
Through what means did the medical examiner's office release this information?
What was the brand on the envelopes found/
What drug was in the envelope?
Was Hoffman found dead in a house?
In what city was his apartment?
How old was he at the time of his death?
What is the last name of CNN's medical correspondent?
And his first name?
What is the last name of the playwright who found his body?
Was someone else with Katz?
What was Hoffman wearing when found?
What did he have on his head?
What persons were Hoffman supposed to pick up that day?
In which arm of Hoffman's was a syringe found?
New York
the New York medical examiner's office 
Philip
Actor Philip Seymour Hoffman
Hoffman
 Philip Seymour Hoffman
Seymour
Philip Seymour Hoffman
yes
The manner of death was ruled an accident, the medical examiner's office said in a statement. 
a statement.
 the medical examiner's office said in a statement. 
"Ace of Spades"

Police found nearly 50 envelopes branded "Ace of Spades" filled with what they believe was heroin in the actor's Manhattan apartment, two law enforcement sources familiar with the inquiry said. 
heroin
Police found nearly 50 envelopes branded "Ace of Spades" filled with what they believe was heroin in the actor's Manhattan apartment, two law enforcement sources familiar with the inquiry said. 
no
Actor Philip Seymour Hoffman, who was found dead February 2 on the bathroom floor of his New York apartment
New York
 New York apartment
46
Hoffman, 46
Gupta
Dr. Sanjay Gupta, CNN's chief medical correspondent
Sanjay
Dr. Sanjay Gupta, CNN's chief medical correspondent
David Katz
Playwright David Katz and another person went to the apartment and found him dead, the official said.
yes

He was expected to pick up his children that day but didn't show up, the official said. Playwright David Katz and another person went to the apartment and found him dead, the official said. 
in a tee shirt and shorts
Police officers found him in a T-shirt and shorts with his eyeglasses still on his head.
his eyeglasses
Police officers found him in a T-shirt and shorts with his eyeglasses still on his head. 
his children
He was expected to pick up his children that day
the left
a syringe in his left arm