Activity under preparation Fighting antimicrobial resistance and strengthening the One Health workforce in Africa This regional action is proposed in the framework of the health pillar of the Global Gateway Africa-Europe Investment Package presented at the 2022 EU-AU Summit, where the AU and EU adopted ¿A Joint Vision 2030¿ declaration with strong commintments on health security and the One Health approach. The regional TEI with Africa on sustainable health security using a One Health approach (as defined by the One Health High Level Expert Pannel (OHHLEP)[1]) has a strong EU member states (MS) support:five EU MS are involved in the TEI (EUR 309 million indicative financial contributions by Team Europe (TE)). This TEI aims to develop further the EU¿s strategic partnership with the Africa CDC, public health agency of the AU, and to align with the AU call for a New Public Health Order in Africa. Priority areas of support have been identified jointly by TE members and Africa CDC. The intention is also to substantiate the partnership with other African organizations for Health security using a One Health approach.The overall objective of this action is to contribute to sustainably strengthen health security in Africa through two main interventions:·A first component will focus on improving the surveillance, prevention and control of Antimicrobial Resistance (AMR) using an integrated, systems strengthening One Health approach at national, regional and continental levels. This component will thereby particularly focus on providing support to the AMR Control programme of the Africa CDC and to its effective roll-out at regional and national levels in alignment with Global standards.·A second component will focus on improving the skills and capacities of relevant professional groups from various sectors in applying the One Health approach,As this will be the second package of action financed by the European Commission under the framework of the TEI with Africa on sustainable Health Security using a One Health approach (TEIA HSOH), it consciously builds on the RIP AAP23 Action for ¿Strengthening One Health surveillance, early detection and prevention of emerging zoonotic diseases in Africa¿ and further substantiates EU¿s strategic partnership with Africa CDC in particular the existing collaboration with its European counterpart the European Center for Disease Prevention and Control (ECDC). Furthermore, it leverages expertise available among European and national institutes and agencies relevant to the One Health approach and TEI Member States¿ development agencies (see section 2.2 on stakeholders).[1] https://www.who.int/news/item/01-12-2021-tripartite-and-unep-support-ohhlep-s-definition-of-one-health