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### Question: Who is at highest risk for Gastrointestinal stromal tumor ?
### Response: Age and genetic factors can increase the risk of having a GIST. Individuals in the age group of 50-80 years are believed to be at the highest risk. The risk of GIST is also increased in people with certain genetic syndromes such as Neurofibromatosis type 1, Carney-Stratakis syndrome and Familial gastrointestinal stromal tumor syndrome. In rare cases, GISTs can be found in several members of the same family.