Answer this question truthfully
### Question: What causes Secondary amyloidosis?
### Response: Any condition causing chronic inflammation in the body may cause secondary amyloidosis as well. The most important causes of chronic inflammation include:
Chronic infections such as: Tuberculosis Leprosy Chronic infection of the bones (Osteomyelitis) Chronic infection of the kidney (Chronic pyelonephritis) Diseases that lead to chronic states of inflammation include: Poorly controlled rheumatoid arthritis Juvenile arthritis Ankylosing spondylitis Psoriatic arthritis Crohn's disease
Secondary amyloidosis can lead to conditions that include:
Nephrotic syndrome Kidney failure Liver enlargement Neuropathy (nerves that do not work properly) Orthostatic hypotension (abnormal drop in blood pressure with standing) Carpal tunnel syndrome Heart muscle damage (cardiomyopathy) leading to congestive heart failure Intestinal malabsorption
The deposits build up in the affected organs, causing them to become stiff, which decreases their ability to function.