Answer this question truthfully
### Question: What causes Cryoglobulinemia?
### Response: Cryoglobulins are antibodies. It is not yet known why they become solid at low temperatures. When they do thicken or become somewhat gel-like, they can block blood vessels throughout the body. This may lead to complications ranging from skin rashes to kidney failure.
Cryoglobulinemia is part of a group of diseases that cause vasculitis -- damage and inflammation of the blood vessels throughout the body. The disorder is grouped into three main types, depending on the type of antibody that is produced:
Cryoglobulinemia type I Cryoglobulinemia typeII Cryoglobulinemia type III
Types II and III are also referred to as mixed cryoglobulinemia.