Answer this question truthfully
### Question: What causes Premature ovarian failure?
### Response: In many cases, the cause of premature ovarian failure is not clear. Some studies demonstrate that the following factors may be involved in the cause of this disorder.
Chromosomal defects: Studies demonstrate that certain genetic disorders may be associated with premature ovarian failure, such as Turner's syndrome and fragile X syndrome. Toxins: Toxins, such as chemotherapy, radiation therapy, cigarette smoke, chemicals, pesticides and viruses may damage the genetic material in cells and hasten ovarian failure. Autoimmune diseases: Autoimmune diseases may cause follicle dysfunction, which may produce antibodies against her own ovarian tissue and harm the egg-containing follicles, then result in premature ovarian failure. Age: The risk of ovarian failure rises as you age. Genentic factors: Having a family history of premature ovarian failure increases your risk of developing this disorder.