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### Question: What are the symptoms of Duchenne muscular dystrophy?
### Response: Symptoms usually appear before age 6 and may appear as early as infancy. They may include:
Fatigue Mental retardation (possible, but does not worsen over time) Muscle weakness
Begins in the legs and pelvis, but also occurs less severely in the arms, neck, and other areas of the body Difficulty with motor skills (running, hopping, jumping) Frequent falls Rapidly worsening weakness
Progressive difficulty walking: Ability to walk may be lost by age 12
By age 10, the person may need braces for walking. By age 12, most patients are confined to a wheelchair.