Answer this question truthfully
### Question: Who is at highest risk for Renal cell carcinoma ?
### Response: Clinical data has suggested that the development of renal cell carcinoma is related to several factors.
Genetic and hereditary risk factors
Von Hippel-Lindau disease
Hereditary papillary renal cell carcinoma
Hereditary leiomyomatosis
Birt-Hogg-Dube syndrome
Hereditary renal oncocytoma
Lifestyle-related and job-related risk factors
Smoking: Tobacco use increases the risk of developing renal cell carcinoma.
Obesity: Clinical surveys demonstrate that renal cell carcinoma has a close relationship with people who are very overweight.
Workplace exposures: Clinical studies have suggested that workplace exposure to certain substances such as asbestos, cadmium, some herbicides, benzene, and organic solvents, particularly trichloroethylene, may increase the risk for renal cell carcinoma.
Drugs: Some studies have suggested that phenacetin (non-prescription pain reliever) and diuretics (medicines uesd to treat hypertension or heart failure by causing the kidneys to remove salt and fluid from the body) may be linked to renal cell carcinoma.
Advanced kidney disease: People with advanced kidney disease, especially those needing dialysis, have a higher risk of renal cell carcinoma. The reasons may be the accumulation of the metabolic toxin.
A family history of renal cell carcinoma
Hypertension
Gender: Men have about twice the risk of developing renal cell carcinoma than women.
Race: Epidemical data shows that African Americans have a slightly higher rate of renal cell carcinoma than other races.