The medieval period of the history of the Tamil country saw the rise and fall of many kingdoms, some of whom went on to the extent of empires, exerting influences both in India and overseas. The Cholas who were very active during the Sangam age were entirely absent during the first few centuries. The period started with the rivalry between the Pandyas and the Pallavas, which in turn caused the revival of the Cholas. The Cholas went on to becoming a great power. Their decline saw the brief resurgence of the Pandyas. This period was also that of the re-invigorated Hinduism during which temple building and religious literature were at their best.

The Hindu sects Saivism and Vaishnavism became dominant, replacing the prevalence of Jainism and Buddhism of the previous era. Saivism was patronised more by the Chola kings and became more or less a state religion. Some of the earliest temples that are still standing were built during this period by the Pallavas. The rock-cut temples in Mamallapuram and the majestic Kailasanatha and Vaikuntaperumal temples of Kanchipuram stand testament to the Pallava art. The Cholas, utilising their prodigious wealth earned through their extensive conquests, built long-lasting stone temples including the great Brihadisvara temple of Thanjavur and exquisite bronze sculptures. Temples dedicated to Siva and Vishnu received liberal donations of money, jewels, animals, and land, and thereby became powerful economic institutions.

Tamil script replaced the "vatteluttu" script throughout Tamil Nadu for writing Tamil. Both secular and religious literature flourished during the period. The Tamil epic, Kamban's "Ramavatharam", was written in the 13th century. A contemporary of Kamban was the famous poetess Auvaiyar who found great happiness in writing for young children. The secular literature was mostly court poetry devoted to the eulogy of the rulers. The religious poems of the previous period and the classical literature of the Sangam period were collected and systematised into several anthologies. Sanskrit was patronised by the priestly groups for religious rituals and other ceremonial purposes. Nambi Andar Nambi, who was a contemporary of Rajaraja Chola I, collected and arranged the books on Saivism into eleven books called "Tirumurais". The hagiology of Saivism was standardised in "Periyapuranam" by Sekkilar, who lived during the reign of Kulothunga Chola II (1133–1150 CE). Jayamkondar's "Kalingattupparani", a semi-historical account on the two invasions of Kalinga by Kulothunga Chola I was an early example of a biographical work.

Pre-historic period
Age of empires (600–1300)
Vijayanagar and Nayak period (1300–1650)
Interregnum (300–600)