There is a wide diversity of plants and animals in South India, resulting from its varied climates and geography. Deciduous forests are found along the Western Ghats while tropical dry forests and scrub lands Deccan thorn scrub forests are common in the interior Deccan plateau. The southern Western Ghats have high altitude rain forests called the South Western Ghats montane rain forests. The Malabar Coast moist forests are found on the coastal plains. The Western Ghats itself is a biodiversity hotspot.

Some of India's famous protected areas are found in South India. These include Project Tiger reserves Periyar National Park, Kalakad - Mundanthurai and Nagarjunsagar-Srisailam Tiger Reserve. Important ecological regions of South India are the Nilgiri Biosphere Reserve, located at the conjunction of the borders of Karnataka, केरळ and Tamil Nadu in the Nilgiri Hills including Mudumalai National Park, Bandipur National Park, Nagarhole National Park Silent Valley National Park, Wayanad Wildlife Sanctuary and Nugu Wildlife Sanctuary and the Anamalai Hills including the Eravikulam National Park, Chinnar Wildlife Sanctuary, Parambikulam Wildlife Sanctuary and the adjacentThe Indira Gandhi Wildlife Sanctuary and National Park of the Western Ghats. Important bird sanctuaries including Ranganathittu Bird Sanctuary, Kumarakom Bird Sanctuary, Neelapattu Sanctuary and Pulicat Sanctuary are home to numerous migratory and local birds. Other protected ecological sites include the backwaters like the Pulicut Lake in Andhra Pradesh, Pitchavarum in Tamil Nadu and the famed backwaters of केरळ formed by the Vembanad Lake, the Ashtamudi Lake and the Kayamkulam Lake.

Banana, "Musaparadisiaca" and "Moringa oleifera" are found extensively in Lakshadweep while coconut plantations provide economic support to the islands. Lashadweep has been declared a bird sanctuary by the Wildlife Institute of India. Crabs, chiefly hermit crabs, parrot fish and butterfly fish are also found on the islands.

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