A potential, but rare, adverse effect of the oral polio vaccine (OPV) is its known ability to recombine to a form that may cause neurological infection and cause paralysis. Clinical disease, including paralysis, caused by vaccine-derived poliovirus (VDPV) is indistinguishable from that caused by wild polioviruses. This is believed to be a rare event, but outbreaks of vaccine-associated paralytic poliomyelitis (VAPP), caused by a circulating vaccine-derived poliovirus (cVDPV), have been reported, and tend to occur in areas of low coverage by OPV, presumably because the OPV is itself protective against the related outbreak strain.

নিষ্ক্রিয় (Inactivated) ভ্যাক্সিন
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Contamination concerns
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