Jean Drèze taught at the London School of Economics in the 1980s, his only full-time post, and at the Delhi School of Economics, and had been Visiting Professor at the G.B. Pant Social Science Institute, Allahabad. Presently, he is an Honorary Chair Professor of the "Planning and Development Unit" created by the Planning Commission, Government of India, in the Department of Economics, University of Allahabad, India. He has made wide-ranging contributions to development economics and public economics, with special reference to India.

He has worked on many issues relating to development economics including hunger, famine, education, gender inequality, childcare, school feeding, employment guarantee etc. His works combine standard economic methods (such as his articles relating to poverty in India) and tools that are used more commonly by anthropologists (such as his work on the village of Palanpur, Moradabad District, Uttar Pradesh, India with Nicholas Stern, Peter Lanjouw and others, which included him living for a period in village under the same conditions as local people, farming a plot of land and keeping animals as recounted with Naresh Sharma in the article "Sharecropping in a North Indian Village", Journal of Development Studies, Oct. 1996). The combination of extensive field work and qualitative analysis of everyday life and poverty, along with quantitative work makes his work distinctive in the field of economics. He uniquely brings to the table his extensive fieldwork—few economists live as much in the country's villages—combined with outstanding analytical skills.

It is not coincidence that Amartya Sen coauthored on a number of major publications on India, given his unique contacts with the grassroots and has even remarked that the "agreeable thing" about working with Dreze is that "he does most of the work and I get most of the credit".

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