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The first legs were played on 13, 14, 20 and 21 February, and the second legs were played on 6, 7, 13 and 14 March 2018.

"Juventus won 4–3 on aggregate."

"Manchester City won 5–2 on aggregate."

"Liverpool won 5–0 on aggregate."

"Sevilla won 2–1 on aggregate."

"Real Madrid won 5–2 on aggregate."

"2–2 on aggregate. Roma won on away goals."

"Barcelona won 4–1 on aggregate."

"Bayern Munich won 8–1 on aggregate."

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