All parts of the plant contain nicotine, which has been extracted and used as an insecticide. The dried leaves can also be used, they remain effective for 6 months after drying. The juice of the leaves can be rubbed on the body as an insect repellent. The leaves have been dried and chewed as an intoxicant. The dried leaves are also used as snuff or smoked. This is the main species that is used to make cigarettes and cigars. A drying oil is obtained from the seed.

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