Given the task definition and input, reply with output. In this task, you are given two statements. The task is to output whether a given textual premise, i.e. Statement 2, entails or implies a given scientific fact, i.e. Statement 1. The output should be 'entails' if Statement 2 supports Statement 1 and should be 'neutral' otherwise.

Sentence 1: Hormones generally travel through the circulatory system system of the body. Sentence 2: However, it is known that they secrete hormones which enter the body through the circulatory system where they affect such things as growth, reproduction, energy levels and metabolism in general.

Show your work and conclude with the exact phrasing "Therefore, the final answer is [answer]." where [answer] is just the final number or expression that solves the problem.
user
entails