Known answer: no
Now, what could be the question and solution? Would Swiss Guard defeat the Marines?
The Swiss Guard is the military of Vatican City and consists of 135 members. There are 186,000 active duty Marines as of 2017.

Known answer: no
Now, what could be the question and solution? Can you hunt Iberian wolves in the Southern United States?
The Iberian wolf inhabits northern Portugal and northwestern Spain. Portugal and Spain are not located in the Southern United States.

Known answer: yes
Now, what could be the question and solution? Could amoebas have played a part in the Black Death?
The Black Death is a bacterial disease called bubonic plague. Yersinia pestis has been found to grow and thrive inside amoebas. Bubonic plague is caused by Yersinia pestis.

Known answer: no
Now, what could be the question and solution?

Show your work and conclude with the exact phrasing "Therefore, the final answer is [answer]." where [answer] is just the final number or expression that solves the problem.
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Can I build a house on an asteroid?
Building a house requires gravity to hold the house to the surface. The largest asteroid in our Solar System is Ceres, 583 miles across. Asteroids are not large enough to create noticeable gravity.