Immune mediated immunological disorders comprise of a group of common conditions that affects the immunomodulatory pathways resulting in lasting and disabling inflammatory conditions. Rheumatological disorders such as rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS) are chronic inflammatory conditions that affect predominantly the musculoskeletal system leading to pain, disability, functional impairment and lowered health related quality of life (HrQoL).