Real Madrid manager Carlo Ancelotti is adamant his side can cope without injured trio Luka Modric, Gareth Bale and Karim Benzema when they face city rivals Atletico on Wednesday night. The two teams come head-to-head in the second leg of their Champions League quarter-final at the Santiago Bernabeu with the scoreline goalless following the first encounter on April 14. Real boss Carlo Ancelotti could start Isco, Jese and Javier Hernandez in the absence of key triumverate Modric, Bale and Benzema - something that doesn't faze the Italian. Real Madrid boss Carlo Ancelotti has hailed his players as the best in the world ahead of their next game . Ancelotti watches his players during the training session ahead of the crucial Champions League tie . Real Madrid full-back Fabio Coentrao (right) and Lucas Silva tussle for possession in a training session . Sergio Ramos (right) comes in with a strong challenge on Jese during Real Madrid's training session . (Left to right:) Daniel Carvajal, Marcelo Vieira and Sami Khedira train ahead of the game with Atletico Madrid . Cristiano Ronaldo (left) and Silva (right) are put through their paces in training ahead of their next game . Real Madrid goalkeeper Iker Casillas warms up during the training session ahead of the Atletico game . Ancelotti is adamant side can cope without injured trio Luka Modric, Gareth Bale and Karim Benzema . Spain international Isco has featured heavily for the Spanish giants this season in a predominately attacking role but Ancelotti is confident that Real's No 23 could sit in front of the defence just like Modric usually does. 'We are missing some important players but it's impossible for us to be more motivated than we are. We have to live with injuries. We did it in the past and it will not hurt our confidence,' Ancelotti said at a press conference. Real Madrid boss Ancelotti could turn to striker Javier Hernandez in their absence against Atletico Madrid . Isco and Jese will also be be hoping to start the Champions League clash against their Madrid rivals . Real Madrid will be without former Tottenham Hotspur midfielder Modric for their Champions League clash . Ancelotti's Real Madrid side will also have to do without attacking duo Bale and Benzema against Atletico . 'Isco has played in Modric's position before and he did very well there. We have plenty of options even without Bale and Benzema. There's James, Jese and Chicharito. James has been doing great, both on the right and in midfield. Chicharito is in fine shape as well, both physically and mentally. 'I will choose the best possible line-up. I will select players that will help the team to play like we did in the first leg. I have the best squad in the world in my opinion.'
Real Madrid face rivals Atletico in the Champions League on Wednesday . Quarter-final tie second leg is nicely poised as first leg ended 0-0 . Luka Modric, Gareth Bale and Karim Benzema are all out injured .