Graft failure of cornea
Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 9 October 2013, last major update February 2011
Copyright: (c) 2004-2013, PathologyOutlines.com, Inc.
- Most corneal transplants are successful and provide long term improvement in visual acuity
- Matching of donor and recipient tissue is not necessary for corneal transplants, since no lymphatics or blood vessels in corneal stroma
- Graft failure may be due to surgical damage of endothelium, immunologic rejection (uncommon) or recurrence of dystrophy
Failed graft with corneal edema
- Fibrosis, vascularization, inflammatory cell infiltrate
- Full thickness scars from prior surgery are present at edge of specimen
- 50% have fibrous retrocorneal membrane
End of Eye > Cornea > Graft failure of cornea
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