When administered intravenously, Lactated Ringer's
Injection provides a source of water and electrolytes.
content resembles that of the principal ionic constituents of normal
plasma and the solution therefore is suitable for parenteral replacement
of extracellular losses of fluid and electrolytes.
Solutions containing lactate are NOT FOR USE IN THE
TREATMENT OF LACTIC ACIDOSIS.
Solutions containing calcium ions should not be
administered simultaneously through the same administration set as blood
because of the likelihood of coagulation.
Solutions which contain potassium should be used with
great care, if at all, in patients with hyperkalemia, severe renal
failure and in conditions in which potassium retention is present.
Solutions containing sodium ions should be used with
great care, if at all, in patients with congestive heart failure, severe
renal insufficiency and in clinical states in which there exists edema
with sodium retention.
In patients with diminished renal function,
administration of solutions containing sodium or potassium ions may
result in sodium or potassium retention.
Solutions containing lactate ions should be used with
great care in patients with metabolic or respiratory alkalosis. The
administration of lactate ions should be done with great care where
there is an increased level or an impaired utilization of lactate ions,
as in severe hepatic insufficiency.
The intravenous administration of this solution can
cause fluid and/or solute overloading resulting in dilution of serum
electrolyte concentrations, overhydration, congested states or pulmonary
edema. The risk of dilutional states is inversely proportional to the
electrolyte concentrations of administered parenteral solutions.
The risk of solute overload causing congested states
with peripheral and pulmonary edema is directly proportional to the
electrolyte concentrations of such solutions.
Clinical evaluation and periodic laboratory
determinations are necessary to monitor changes in fluid balance,
electrolyte concentrations and acid-base balance during prolonged
parenteral therapy or whenever the condition of the patient warrants
Caution must be exercised in the administration of
parenteral fluids, especially those containing sodium ions, to patients
receiving corticosteroids or corticotropin.
Potassium containing solutions should be used with
caution in the presence of cardiac disease, particularly in digitalized
patients or in the presence of renal disease.
Solutions containing lactate ions should be used with
caution as excess administration may result in metabolic alkalosis.
Do not administer unless solution is clear and container
is undamaged. Discard unused portion.
Reactions which may occur because of the solution or the
technique of administration include febrile response, infection at the
site of injection, venous thrombosis or phlebitis extending from the
site of injection, extravasation and hypervolemia.
If an adverse reaction does occur, discontinue the
infusion, evaluate the patient, institute appropriate therapeutic
countermeasures and save the remainder of the fluid for examination if
In the event of overhydration or solute overload,
re-evaluate the patient and institute appropriate corrective measures.
Dosage and Administration:
Lactated Ringer's is administered by
intravenous infusion. It may also be administered subcutaneously. The
amount to be infused is based on replacement of losses of extracellular
fluid volume in the individual patient. Up to 3 times the volume of
estimated blood loss during and after surgery can be given to correct
circulatory volume when there is only a moderate loss of blood.
Additives may be incompatible. Consult additive
manufacturer. When introducing additives, use aseptic technique, mix
thoroughly and do not store.
The presence of calcium limits their compatibility with
certain drugs that form precipitates of calcium salts, and also
prohibits their simultaneous infusion through the same administration
set as blood because of the likelihood of coagulation.
Parenteral drug products should be inspected visually
for particulate matter and discoloration prior to administration,
whenever solution and container permit.
Instructions For Use:
Tear outer wrap at notch and remove solution
container. If supplemental medication is desired, follow directions
below before preparing for administration. Some opacity of the plastic
due to moisture absorption during the sterilization process may be
observed. This is normal and does not affect the solution quality or
safety. The opacity will diminish gradually.
To Add Medication
1. Prepare additive port.
2. Using aseptic technique and an additive delivery
needle of appropriate length, puncture resealable additive port at
target area, inner diaphragm and inject. Withdraw needle after injecting
3. The additive port may be protected by covering with
an additive cap.
4. Mix container contents thoroughly.
Preparation for Administration
(Use aseptic technique)
1. Close flow control clamp of administration set.
2. Remove cover from outlet port at bottom of container.
3. Insert piercing pin of administration set into port
with a twisting motion until the set is firmly seated.
NOTE: See full directions on administration set carton.
4. Suspend container from hanger.
5. Squeeze and release drip chamber to establish proper
fluid level in chamber.
6. Open flow control clamp and clear air from set. Close
7. Attach set to venipuncture device. If device is not
indwelling, prime and make venipuncture.
8. Regulate rate of administration with flow control
When ready for use, remove from over wrap. Inspect for
minute leaks by squeezing container firmly. If leaks are found, discard,
as sterility may be impaired. Protect from freezing and excessive heat.
Store at controlled room temperature.
IMPORTANT: CONTAINS NO PRESERVATIVE.
SINGLE DOSE. DISPOSE OF UNUSED CONTENTS.
WARNING: DO NOT USE FLEXIBLE CONTAINER
IN SERIES CONNECTIONS.
Protect from freezing and excessive heat
(any temperature above 40°C / 104°F). Store at controlled room
temperature. (15° to 30°C / 59° to 86°F).
Keep Out of Reach of Children
Federal law restricts this drug
to use by or on the order of a licensed veterinarian
Flexible plastic bag of 1000 ml. Contains no preservatives.
Vetivex Veterinary Lactated Ringer's Injection, USP
Dechra Veterinary Products