J. Craig Venter is transforming our understanding of the world and life itself.
The man who mapped the human genome first became fixed on understanding life at the cellular level (and beyond) as a Navy Corpsman in Vietnam. In 2013's "Life at the Speed of Light: From the Double Helix to the Dawn of Digital Life," he writes:
"As a young corpsman in Vietnam, I had learned to my amazement that the difference between the animate and inanimate can be subtle: a tiny piece of tissue can distinguish a living, breathing person from a corpse; even with good medical care, survival could depend in part on the patient's positive thinking, on remaining upbeat and optimistic, proving a higher complexity can derive from combinations of living cells."The book follows "A Life Decoded" and continues to explain how the field of genomics is "blending biology and engineering approaches" in gene-splicing, recombinant DNA and creation of synthetic life. Venter explains how and why he continues his "empowering extraordinary journey," including when he and his team announced the first functioning synthetic genome, May 20, 2010:
"We also discussed our larger vision – namely, that the knowledge gained in doing this work would one day undoubtedly lead to a positive outcome for society through the development of many important applications and products, including biofuels, pharmaceuticals, clean water, and food products. When we made the announcement, we had in fact already started working on ways to produce vaccines and create synthetic algae to turn carbon dioxide into fuel."Venter says his team's work was built "on earlier work and ideas that had originated from a range of talented teams, stretching back over many decades."
In "Life at the Speed of Light," he carefully maps the history of his science, starting with a seemingly simple question posed by the father of quantum mechanics, Erwin Schrödinger: "What is Life?"
He explains the work of James Watson and Francis Crick, Motoo Kimura, Lucy Shapiro, Barbara McClintock, Robin Hook, Frederick Sanger, Arthur Kornberg and dozens of other scientists, all within the context of thinkers and philosophers like Aristotle, Francis Bacon, Descartes, Erasmus and Charles Darwin, Pasteur, Einstein and Isaac Asimov.
Venter reminds us of when the first DNA virus was sequenced and artificially copied and activated by Kornberg, recognized publicly in 1967 by President Lyndon B. Johnson, who said the work, "unlocked a fundamental secret of life ... It opens a wide door to new dimensions in fighting disease, in building much healthier lives for all human beings."
Venter missed the quote and the news at the time because he was serving in Da Nang, Vietnam. That was nearly 50 years ago.
After Vietnam, Venter "became convinced of the direction my future my life should take," as he writes in "A Life Decoded." He used the G.I. Bill to pursue his education and he has not looked back.
In fact, he has continued to look within – literally examining his own life. And he has looked forward into the future: considering metagenomics, biological teleportation and support for life on Mars.
He promises the future "will be as empowering as it is extraordinary." The dawn of digital life, he says, has the potential for unlocking evolution and creating "a new era of biological design," where vaccines can be sent anywhere in the world at the speed of light during a pandemic and where climate change and other manmade problems can be countered with help from artificial and enhanced intelligence.
(I became interested in reading more by and about Dr. Venter after reading "Abundance" by Diamandis and Kotler.)