People who have been exposed to vinyl chloride or to thorium dioxide (Thorotrast) are more likely to develop these cancers (seeLiver cancer risk factors). Some other cases are thought to be caused by exposure to arsenic or radium, or to an inherited condition known as hereditary hemochromatosis. 
People who have been exposed to certain chemicals, toxic substances or have an inherited condition, have a higher risk of developing these cancers (seeLiver cancer risk factors). 