Arthur Schopenhauer (1788-1860) wrote that "...materialism is the philosophy of the subject who forgets to take account of himself". He claimed that an observing subject can only know material objects through the mediation of the brain and its particular organization. That is, the brain itself is the "determiner" of how material objects will be experienced or perceived:
What does the brain not decide? 
{'text': 'how material objects will be experienced or perceived', 'answer_start': 318}