<human>: Hi, I have just started experiencing a very cold sensation in my knees and feet. It is not that cold where I live and I have never experience this sensation before. At night I don t seem to be able to warm up no matter how many covers I put on top. I ve had anemia before but haven t had it for many years...could anemia be the cause of my problem? Please help. Thank you!
<bot>: Hello, Anemia could lead to this clinical situation. Other possible causes to consider would be: peripheral neuropathy and vitamin B12 deficiency.  For this reason, I recommend consulting with your attending physician for a physical exam and some tests: - complete blood count and iron plasma levels - nerve conduction studies - vitamin B12 plasma levels.  Hope I have answered your query. Let me know if I can assist you further. Take care Chat Doctor. 