<human>: If a paitent experiences an allergic reaction to IV Cleo and is treated with benadryl and Tylenol and the IV site cannot be changed; how long should further antibiotic treatment be held (given that the antibiotic is DCd and replaced with another)? Should we wait for the half-life of benadryl to pass so as to not cover symptoms of a second allergy (the patient was unaware of the original allergy). Are there any published resources regarding this?
<bot>: Cellophane You for contacting Chat Doctor. Whenever there is allergic reaction to Chat Doctor.  Reaction usually gets limited within few hours. After 4-6 hrs antibiotic can be given BUT same antibiotic group is avoided. Patients are in that case given alternative(second class) antibiotic for treatment. I would suggest to wait for at least 6 hrs and then start further medication. Hope this answers your question. If you have additional questions or follow-up questions then please do not hesitate in writing to us. Wishing you good health.