<human>: hi Doc, i am a 33 years old female and a blood group o positive. been trying for a baby with my husband since november 2012 and still not yet pregnant. my husband is blood group b positive and he is 31 year old. what can we do to get pregnant. i have been on contraceptives. please help.
<bot>: Hallow Dear, If you have failed to conceive after such a long period of fair trail, you need to undergo complete work up. Usually, after discontinuing contraceptives, the fertility returns soon. Your blood groups are not responsible for your infertility. Please undergo following investigations:1. Evidence for egg release (ovulation): There are many tools available for this. Home ovulation detection kit can also inform you whether you ovulate or not; however, at least once, ultrasonographic evidence of ovulation is desirable. It will also inform the size of follicles before ovulation. Follicles of the size between 18 mm and 21 mm release healthy eggs having more possibility of successful pregnancy. Also, endometrial thickness can be assessed by ultrasonography. Endometrium of thickness between 9 mm and 14 mm are most conducive for successful implantation of the fertilized egg. Microscopic study of the endometrium before the menstruation can inform you whether you are ovulating or not. Hormonal profile is also very useful in assessing the reproduction function, particularly ovulation. An ovulation can be tackled by induction of ovulation by Camphene citrate or HMG/Chat Doctor combination as per the indication. 2. Laparoscopy and/or Hysterosalpingography will inform about the patency of the reproduction tract. Former one can inform about the anatomical condition of the reproduction organs. Hysteroscopy can find out any intrauterine abnormality if present. 3. Husbands semen examination after four days abstinence for the sperm quantity and quality. If any pathology is found, it needs attention. However, if there is no abnormality, plan your intercourse on and around the day of ovulation. Still if there is no result, it becomes a case of unexplained infertility which can be managed by Artificial Reproduction Technique. Please report to your Gynecologist and/or Infertility Specialist. I hope this provides you required guidance. 