<human>: My father just got diagnosed with lupus and is very concerned plus then the doctors are trying to rule out all the other diagnoses that he is getting hit with along with the Lupus diagnoses. Polycythemiavera and cartine transporter deficiency.Plus my son now has two grandparents  on both sides my husbands and mine with Lupus, what are his chances?
<bot>: Hello, Thanks for posting on Chat Doctor, SLE/lupus has a modest recurrence rate in families: 8% of affected patients have at least one first-degree family member (parents, siblings, and child Chat Doctor.  SHE is influenced both by genetic and environment, so saying the chances of your son ending up with SHE are there but to a lesser extent (i.e. might not even occur). He may need from year to go through check-ups to see if early signs of SHE could be identified. Hope this helps