<human>: My stepfather had a kidney transplant on Tuesday. He was on dialysis for 4 years and his creatine levels were around 10 before the transplant and after it was at 7. It came down to 3 yesterday and is now back up to 4. The doctors aren t telling us much, is this a sign of rejection or failure? Could it be the meds he is on for anti rejection?
<bot>: Hello. Thanks for asking to Chat Doctor. Brief answer: Indicate transplanted kidney is working fine. Detailed answer: No, sign of rejection or failure would be building up of creatinine in the blood rather becoming low. Creatinine is actually an end waste metabolite that is usually excreted by normal kidneys. The anti-rejection medications may cause the transplanted kidney to fail at high doses. But at low effective doses, it prevents rejection and aids in proper functioning of kidney. Do not worry as in your stepfathers case, everything seems to be fine. Hope this answers your query. Take care.