<human>: I AM 60, AN RN AND HAVE BEEN RELATIVELY HEALTHY. I WAS TOLD IN THE 90S I HAD FIBROMYALGIA BUT I HAVE NEVER RECEIVED TREATMENT OR MEDICATIONS FOR IT. RECENTLY I HAVE BEEN VERY TIRED AND MY WHOLE BODY HURTS ALL OVER. I AM ON THYROID MEDICATION, LISINOPRIL AND WELLBUTRIN AT THIS TIME. ANY SUGGESTIONS FOR ME?
<bot>: Hello, Ok, I have non-functional opiate receptors. The conventional textbook information on fibromyalgia as non-functional opiate receptors works fine for me.  Then again, the data imply that most people with fibromyalgia are depressed and trying a different anti-depressant is often needed for depression. So, Lisinopril isn't necessarily effective and can both not work and lower the blood pressure too much.  https://www.ncbi.nlm.nih.gov/pubmed/2442549, only a quarter of the dose of lisinopril gets in, and it varies between a sixth and a third; some days twice as much as other days. Thyroid medicine has to be adjusted periodically. Then, anti-inflammatories, nerve dampers such as lyrics, and mainly exercise daily. Hope I have answered your query. Let me know if I can assist you further. Take care Chat Doctor. 