<human>: Hi I am 34 years male, undergone treatment till date since September, 2011 for Lichen planus of nails . My Dr. gave me different doses methotraxate (5, 7.5 and 10 mg) depending upon the sgpt report and condition of nails. I have gone blood test for my liver SGPT are as: sep, 2011: 61, oct, 2011: 78, dec, 2011: 78, oct, 2012: 101, dec, 2012: 121 Please suggest me any serious things indicates these reports.
<bot>: Dear rocky100007, Lichen plans is usually treated with Corticosteroid skin creams in mild cases and with oral Prednisolone or Metronidazole along with Ultraviolet Light therapy in severe cases (Not methotrexate). Prolong use of Methotrexate is known to cause Liver injury which is indicated by increase in level of SGPT(Normal range: 7-56). Since your SGPT is consistently increasing, it is advisable to stop or reduce dose of Methotrexate and start with other treatment as I have mentioned initially as per your symptoms demand. Hope this helps. Take care !