<human>: Extreme fatigue , chest tightness, body feeling heavy, dry eyes , unable to concentrate, comeback pain for last 6 years. Cholesterol around 230 all other tests turned negative. No Bp no sugar. Good appetite and sleep. Pain all over body. Doctor put me on anti represents for a long time (wellbutrin etc) no improvement. Male 46. Frequent flu like symptoms but no temperature rise.
<bot>: Hello, welcome to Chat Doctor. Your symptoms like fatigue, chest tightness, body feeling heavy, Chat Doctor.  Bupropion is effective for anxiety and depressive symptoms. Some time patient (approx 40% cases) did not improve with initial treatment, in that case one of the following steps are used:-To rule out any medical condition leading to existing symptoms-Checking compliance to treatment: Take medicine regularly: as medicine used to show effect after 4-6 weeks of continuous use.-Detection and correction of vitamin deficiency (especially vitamin B12): so take vitamin supplement and fruits/milk in diet.-Screening of thyroid dysfunction: Get serum T3/T4 and TSH level done-Increase the dose of current medicines-Change of existing medicine-Addition of other medicine-Addition of psychotherapy in treatment It is better to get re evaluated by psychiatrist and follow above recommendations. Wish you all the best. 