<human>: I have sickle beta thalassimia diease and I have had a sickle crisis before and I have been having them for almost 2 years repeated ly is this dangerous. And do I need to go the hospital. Every time I have a crisis I seem to stay sick and catch things easily
<bot>: Hi, Thanks for asking. Based on your clinical history and query, my opinion is as follows:1. Yes, repeated pickling/ sickle crisis permanently deforms the RBC's, which cannot regain its original discoid shape after cessation of crisis.2. Deformed RBC's cannot pass through the splenic microcirculation which can lead to Chat Doctor.  3. Hemolysis is also known to occur with this situation worsening the anemia.4. Yes, you need to get a consultation and appropriate treatment. Hope it helps. Any further queries, happy to help again.