<human>: Lower back pain in center of back.  Some times painful but since I stated taking Glucosamine/Chrondrotin it is not nearly as bad.  I have trouble standing up right, especially f carrying any weight in my hands.  At night I do not have pain but feel uncomfortable when sleeping on my back
<bot>: Thank you for the question. As you have not mentioned your age or your sex both of which might be relevant, I have to say that there could be a few possibilities:1) lumbar spondylosis: disc protrusion from the lumbar spine maybe l4-l5. You should have a MRI and definitely show an orthopedic surgeion2) Arthritis(often/rheumatoid):Analgesics like ibuprofen 800 mg twice a day are the standard treatment for both. However, you should definitely have it checked out by your doctor. A simplex ray and blood tests for RA factor and anti-cccp should suffice3) Spinal TB: A rare complication especially if you live in a developed country. A MRI will give the picture