<human>: Hi, Good Evening, Would be obliged if you can share some expert advice on the below: Macroscopic Description: Received 7 irregular grayish white to dark brown soft tissue fragments measuring from 0.3 to 0.4 cm - 7 all. Microscopic Description: sections show fragments of gastric mucosa with infiltration of the lamina propria by a maligant neoplasm composed of hyperchromatic and pleamorphic polyhedral cells forming glands or as cords against a desmoplastic stroma. focally vocuolated signet ring cells are seen in between the neoplastic glands. focally some inflammatory granulation tissue with interspered neoplastic glands are also noted. Impression: MODERATE TO POORLY DIFFERENTIATED (GRADE III TO IV) ADENOCARCINOMA , GASTRIC (ENDOSCOPIC) BIOPSY. kindly advice whether to operate or not, if operated the life after it ???The patient age is 63 yrs. Regards, Nasir
<bot>: Hi. Good evening.... Nasir..., welcome to Chat Doctor., Thank foe Your query..., Adenocarcinoma Grade III to IV...., Usually severe one..., Age of patient is 63 years...... Surgery is not suggestible...., but first exclude metastasis..., That is spreading to surrounding tissue...and distant lymph nodes..., Depend on this only Surgery is advisable....and Age is also not favorable...,Anyhow consult good Oncologist and go accordingly....o.k. good luck...,