<human>: Good morning Dr I am Prakash Rana ,38 years old, from Nepal,now I am suffering from mylofibrosis and taking allopathic drug Hydroxyurea since three months from Medanta Hospital India,Now I want to know curative or better treatment about this Disease.
<bot>: **1. Since you are already a diagnosed case and under medical supervision thus they must have excluded any secondary cause of the disease, and provided with necessary treatment and management, and because treatment is symptomatic, as such following things must be kept in mind:. Allogenic Stem Cell Transplantation is the definitive curative management. If you are asymptomatic, observation is best. If uric acid and hemolysis is there then a hyperglycemic Chat Doctor.  JAK inhibitors [ruxolitinib] have shown promising results in treatment of myelofibrosisPS. Management of individual symptoms in myelofibrosis is very difficult and there is no evidence of benefit for any of the conventional treatments for the same.2. So you need Immunomodulator [Malayan] Nikita to help strengthen your Immune system