<human>: hi ia 40 male no h/o any chronic disease .2years back had disc prolops hith accidental finding of moderrate spleenomegaly .fatty liver grade 2 .my all investgation wnl.serology ...neg all infections ruled out .no portal htn .what cause of spleenomegaly what to do further
<bot>: Hi dear as all your routine tests and serology are normal would go for some rare possibilities it can be infectious mononucleosis, a viral disease - a serology for cytomegalovirus is to be done endocarditis (inflammation of inner layer of heart can be a cause -2d echo is to be done to rule out you have not mentioned your Chat Doctor. Blood cancers like leukemia can be a cause of it, investigations should be done to rule out the possibility, especialy Hopkins lymphoma is associated with metabolic disorders, such as Gaucher disease and Niemann-Pick disease-are very rare, but genetic reading is to be done to rule out this rare cases are rare, but they do happen, a thorough investigation is to be done to find out the cause in your case