<human>: hello, Doctor I have been breaking out in welts and hive for the last three years. I break out with these welts when I get upset or anxious.  I have been to an dermatologist and he recommended an antihistamine (Zyrtec) which I have been taking for the last three years. Im worried its something more serious should I be worried.Nicole
<bot>: Hello Nicole, Thank you for asking at Chat Doctor. I went through your history and would like to make suggestions for you as follows:1. If all the times cause of your hives and welts is getting upset/anxious, it is possible they are stress-related.2. I would agree with your doctor that such hives are self-limiting and antihistamine such as levocetirizine/cetirizine etc. help them to improve early.3. If you have symptoms such as frequent diarrhea, palpitations, weight loss, excess sweating, increased appetite, etc. also, I would suggest you testing for thyroid disorder (hyperthyroidism), which may be causing repeated periods of anxiousness also. Some hives are related to thyroid abnormalities as well.4. If you have not such physical symptoms, seeking a professional help from psychologist/psychiatrist may also help you.5. Regular relaxation practice say help you in a long run. Hope above suggestions will be helpful to you. Should you have any further query, please feel free to ask at Chat Doctor. Wish you the best of the health ahead. Thank you & Regards.