<human>: Hello, 3 months ago i recieved the first injection of rooster comb for knee of what was suppose to be a series of 3 shots, by the second shot i started to experience severe joint pain throughout my entire body, convinced i was having a reaction to the shots i refused the 3rd, Dr. put me on prednizone, 40m a day, after about 3 wks i reduced it to 10m as i was now having s/e to the pred, a little while later the joint pain was so bad i could barely move, my wife had to help dress me. Finally got in to see rheumatologist, after 20 viles of blood work she has diagnosed me with having spondylopathy & put me on methotrexate , do you think the knee injections are responsible or mere coincidence?
<bot>: Dear patient Why was the injection of corticosteroids given to your knee? Was it for osteoarthritis or nonspecific pain? If corticosteroids injection is given intra-articular it gives pain for initial 2 to 3 days due to inflammation and subsequently pain decreases. If pain continues after 3 days there are two reasons 1. Corticosteroids were not effective 2. There is little possibility of infection. I would like to advise local ultrasound to rule out collection. If its normal infection is less likely. Methotrexate is given for systemic inflammatory arthritis with Good recovery. Intra-articular corticosteroids injection will not lead to systemic inflammatory arthritis.