The research protocols that have been released by leading vaccine manufacturers are not designed to show whether the vaccines prevent transmission, hospitalizations, or deaths, but only whether they reduce symptoms,” writes William Haseltine. Of course, they cannot stop the pandemic unless they do halt transmission. Is vaccination more or less effective than pre-exposure or post-exposure prophylaxis (PreP or PEP), modeled on protocols for HIV/AIDS? A trial with a head-to head comparison would be needed. How safe are the vaccines? It is of course impossible to rule out long-term complications when testing has lasted only a few months. The most important is the effect on fertility, which would require years to manifest. The published protocols do not mention how this will be monitored. This is especially concerning when governments are apparently determined to vaccinate most of the world’s population over a very short period.