Subamniotic haemorrhage, a possible new presentation of fetal and neonatal alloimmune thrombocytopenia.

The study titled, 'Subamniotic Hemorrhage, a Possible New Presentation of Fetal and Neonatal Alloimmune Thrombocytopenia' Giesbers et al reports that histologically this hematoma consisted mainly of degenerated blood with fibrin and nucleated fetal erythrocytes under the amnion. The authors state that the placental parenchyma had a normal maturation with focal ischemia, a low-grade chronic villitis of unknown etiology and part from the subamniotic hematoma, a subchorionic hematoma was also present in the maternal compartment. The nucleated fetal erythrocytes were also visualized by an immunohistochemical staining for fetal gamma-globulin (CD71) and it was shown in Fig. 4c. There are a few concerns with the observations reported by Giesbers et al.