Plasma pTau 181 concentrations in middle‐aged, community‐dwelling, racially and ethnically diverse adults

Plasma biomarkers for Alzheimer’s disease (AD) are becoming more widely available, with pTau181 emerging as among the most sensitive and specific. There is a lack of data characterizing plasma pTau181 concentration in diverse cohorts and in middle age. The purpose of this study was to examine the association of age, sex/gender, race/ethnicity, APOE genotype, and memory with plasma pTau181 in the Offspring Study of Racial and Ethnic Disparities in Alzheimer’s Disease study, a population‐representative study of AD risk in middle aged adults.