Can immunization against SARS-CoV-2 be the triggering factor for seizures?


 Introduction: Neurotropic and neuroinvasive tropism of coronaviruses have been described in humans. Neurological disorders reported in the current literature in patients with coronavirus infection include: febrile seizures, fatigue, cognitive impairment, asthenia, hyposmia, ageusia, seizures, loss of consciousness, encephalomyelitis and encephalitis, Guilain-Barré syndrome, optic neuritis, peripheral neuropathies, among others. In contrast, reports of epileptic seizures after immunization against SARS-CoV-2 are interrogated.

 Case Report: We report the case of a 12-year-old student, healthy, without comorbidities, who, 22 hours after the second dose of an immunization against SARS-CoV-2, started the first seizure.

 Conclusion: The time interval between vaccination and the outbreak of crises, we believe, should be taken into account in the present case; mainly because she was a healthy teenager, with no recent previous factors that could serve as triggers.