Head‐to‐Head comparison between Philips Gemini TF64 and Siemens Biograph Vision 600 for brain amyloid Centiloid quantitation

The Centiloid (CL) scale calibrates the beta‐amyloid (Aβ) deposition from different PET tracers to a standardised 0‐100 CL unit scale. As imaging sites update their PET cameras, most are switching to digital detector systems with superior resolution and sensitivity that may affect quantitation. This has significant implications for dementia clinical trials. In this study, we examine the impact on CL quantification between Philips Gemini TF64 and Siemens Biograph Vision 600.