Diabetes is related to cognition but not plasma amyloid‐β 42/40 in an African American cohort

The prevalence of clinical Alzheimer’s disease (AD) and type 2 diabetes is higher in African Americans (AA) relative to non‐Hispanic White Americans. Although diabetes is a risk factor for Alzheimer’s clinical syndrome, it is unclear whether diabetes associates with amyloid‐β, a pathological hallmark of AD. We investigated whether diabetic status was associated with age‐related decline in plasma amyloid‐β (Aβ) 42/40 ratio and cognition in a predominantly dementia‐free AA cohort.