Electrochemical study of Bismuth heavy metals using the cyclic voltammetry method in anti-protozoal

Bismuth oxides are well-known electro-catalysts in fuel cells systems; they are usually used as anodic materials for the oxidation of low molecular weight alcohols. The utilization of BiO2 and MnO2 as catalysts in the pharmaceutical analysis is analytical method for the determination of heavy metal antibacterial agents in Pharmaceutical Dosage form is developed. The method is based on the voltammetric determination of heavy metal using Bidified platinum electrode by Bismuth oxide. The two components are oxidized at the Bidified electrode surface with the development of current that is linearly proportional to their concentrations in the range of 7.04*10-7- 1*10-3 M heavy metal. The oxidation reaction of the two components is pH-dependent, in which the buffer used is Britton-Robinson at pH = 7.00 where maximum peak current and maximum peak separation is obtained. The regression factors obtained from the calibration curves are 0.9812. The method of analysis was validated, where the limit of detection (LOD) and the limit of quantitation (LOQ) were calculated to be 1.44*10-4 M, 4.36*10-4 M and 1.27*10-4 M, 3.84*10-4 M respectively, the percentage recovery of both components was also calculated to 77 % for heavy metal.