The Combined Effect of STEMB and Immunomodulatory Substance in the Blood Profile of Cows at the 15th Day Post-Partum.

The objective is to determine the morphological and biochemical blood parameters of cows at the 15th day postpartum with the separate and combined use of an Embryonic Stimulator (STEMB) and an immunomodulator (Immunopharm). In all studies, there were three experimental groups. For the first experimental group, the STEMB solution was administered to Holstein cows at 30 days before delivery, injected thrice subcutaneously at 7 days’ intervals and at a dosage of 0.075 ml/kg of body weight. The second experimental group was administered with the immunomodulator thrice intramuscularly at 7 days’ intervals and at a dosage of 6 ml per cow, starting 30 days prior to delivery. Finally, the third experimental group of cows were administered the drugs STEMB and Immunopharm combined while using the same dosage (0.075 ml/kg and 6 ml/cow respectively) and scheme (Thrice, 7 days’ interval, starting at 30 days before deliver) as the two other groups. It was found that the combined use of STEMB and Immunopharm improved the blood cell composition; increased amount of monocytes, segmented neutrophils, hemoglobin, total protein, alpha-globulins, immunoglobulins (A, M, G) and also reduced the indicators of ALT and AST enzymes to the threshold level. It has been demonstrated that the combined use of STEMB and Immunopharm are optimal for the prevention of birth and postpartum complications as well as providing an improvement in the blood cell composition.