Characteristics of primary age‐related tauopathy defined by neuroimaging biomarkers

Primary age‐related tauopathy (PART) is a neuropathological entity with neurofibrillary tangles (NFTs) in the absence of amyloid (Aβ) plaques in the brain. Recent advance of neuroimaging makes it possible to identify PART in living human brain. We tried to investigate the frequency and clinical characteristics including rate of cognitive decline of non‐demented older adults with PART defined by neuroimaging biomarkers.