Microstructural changes in the white matter tracts of the brain due to mild cognitive impairment

Mild cognitive impairment (MCI) is an early stage of memory loss or cognitive decline and progresses to Alzheimer’s disease at a rate of about 15% per year. It is important to study the effects of MCI on the brain. Here we present a novel along‐tract analysis of microstructural brain metrics computed from diffusion MRI. We extract, map, and visualize the profile of microstructural abnormalities on 3D models of fiber tracts, yielding fine‐scale maps of the effects of MCI.