The gut microbiome is associated with markers of cerebral small vessel disease

Cerebral small vessel disease (cSVD) is a major cause of cognitive impairment and dementia in the elderly. Dysregulation of the gut microbiome has been linked to cSVD, stroke, and dementia in human and animal studies. However, whether dysbiosis is associated with markers of cSVD is unclear. We aimed to assess the cross‐sectional association between the gut microbiome and MRI markers of cSVD and executive function in the Framingham Heart Study (FHS).