Does Conditioned Pain Modulation Predict Pain Outcomes?

pathway, or the pain-inhibits-pain phenomenon, and repre-sents the net effect of the facilitatory and inhibitory functions of the descending pain pathways. The measurement of CPM magnitude quantifies the efficacy of the brain in activating endogenous analgesia, which is thought to be impaired in the context of chronic pain. The following narrative review explores the scientific evidence for and against using CPM to Learning Objectives: After participating in this continuing professional development activity, the provider should be better able to: The authors sought to investigate the consequences of the coronavirus disease-2019 (COVID-19) pandemic on pain and well-being for individuals with chronic pain, and the impact on the health of young adults with chronic pain. A longitudinal study compared pain, psychological functioning, and substance use before and during the pandemic. The study included 196 young adults, ages 18 to 24 years (79.6% females) with chronic pain. Participants reported on pain, anxiety, depression, and substance use before the pandemic (October 2018 to August 2019) and during the pandemic (October 2020 to November 2020). Participants also reported on their assessment of COVID-19 exposure and its impact.