Efficacy and Safety of PRC-063 for Attention-deficit/hyperactivity disorder: A systematic review and meta-analysis from randomized controlled trials

Review question / Objective: We conducted a systematic review and meta-analysis from randomized controlled trials to evaluate the efficacy and safety of PRC-063 for Attention-deficit/hyperactivity disorder. Condition being studied: Attention-deficit/hyperactivity disorder (ADHD) is diagnosed with the core symptoms including inattention, hyperactivity and/or impulsivity.Current treatment options for ADHD include pharmacological treatment， behavioral therapy, and combination therapy of the two treatments above. Methylphenidate (MPH) and the extended-release formulation, as a first-line pharmacological treatment of ADHD, have been widely researched in the world.