Effect of Cognitive Decline on Facial Appearance Revealed by Artificial Intelligence

We have demonstrated that Cognitive function has a stronger correlation with perceived age than with chronological age (Umeda‐Kameyama et al. 2020). Based on this study, we hypothesized that cognitive decline appears in one's face, and have demonstrated the possibility of artificial intelligence to detect cognitive decline using a facial photography (Umeda‐Kameyama et al. 2021). Perceived age can be a useful biomarker in the geriatric field, however it requires many specialists' judgement. We aimed to determine if artificial intelligence can produce reliable perceived age easily.