Pregnancy management and outcome after uterus transplantation.

Uterus transplantation is a novel approach in women whose uterus is absent or severely abnormal. However, it is still an experimental procedure that poses risks to both the mother and baby. To date, 32 live births after uterus transplantation have been reported in peer-reviewed journals with several maternal, fetal, and neonatal complications. The most common complications were preterm delivery, hypertensive disorders and placenta previa. Four patients experienced episodes of transplant rejection during pregnancy. The appropriate management of complicated and non-complicated pregnancies is still controversial. In this review, obstetric outcomes after uterus transplantation and optimal management during pregnancy are discussed in light of the available data. This article is protected by copyright. All rights reserved.