Methodological gaps in clinical dementia research

Evidence‐based decisions allow to compile clinical guidelines, or to approve or refund new treatments or diagnostic procedures. Different evidence‐to‐decision (EtD) procedures exist to define recommendations based on evidence. However, often data are not eligible to such EtDs due to faults in the methodology that generated them. This is a relevant and upstream problem hurdling the transfer of knowledge. Aim of this work is to outline these methodological problems to help overcoming such concrete hurdle to knowledge transfer.