Default‐mode connectivity mediates the association between cardiovascular and metabolic risks and cognition: a pilot study

Prior studies have linked increased vulnerability to cognitive decline later in life with exposure to cardiovascular and metabolic disease risk factors. Further, these classic risk factors are associated with alteration to brain structure and function. This project investigates whether altered default‐mode network (DMN) functional connectivity (FC) mediates the association between cardiovascular and metabolic (CVM) health and cognition.