Implementation of Blood‐Based Biomarker Assays to Deliver Consistent and Comparable Data

Implementing biomarkers for Alzheimer’s Disease (AD) is an important area of research that will enhance the ability to accurately characterize the disease with the goal of earlier detection and treatment. Analytical validation is the first step to determine the measuring range, specificity, precision, and matrix effects of biomarker assays. Studies on analyte stability and performance bridging when key reagents are changed are critical to deliver reliable and consistent data over time. The goal of these studies is to demonstrate the performance of the assays implemented in the NCRAD Biomarker Assay Laboratory (BAL).