Clinical and Surgical Management of Zollinger-Ellison Syndrome: A Literature Review

Zollinger-Ellison Syndrome is a rare disease caused by tumors called "Gastrinomas", causing high levels of gastrin that produces acid hypersecretion and even gastric ulcers. We present a 20-year-old patient with a 2-month history of pain in the epigastrium accompanied by nausea, vomiting, and weight loss with a history of upper gastrointestinal bleeding from a duodenal ulcer, which on physical examination revealed a tumor in the epigastrium. Contrast-enhanced abdominal CT showed a tumor mass in the tail of the pancreas. She underwent surgery, performing a corporocaudal pancreatectomy and splenectomy, with favorable post-surgical evolution. The anatomopathological study reports pancreatic gastrinoma.