Correlation between the severity of coronary artery disease and CHA2DS2VASc Score in patients with non-valvular atrial fibrillation

Background: Nonvalvular atrial fibrillation (NVAF) frequently coexists with coronary artery disease (CAD) as they share similar risk factors and pathophysiology. However, the relation between the CHA2DS2VASc score and CAD in patients with NVAF is not studied well. The objective of this study is to evaluate the correlation between the CHA2DS2VASc score and the coronary angiographic findings in NVAF patients. Methods: This is a prospective, randomized, single-center study that included all patients with NVAF that attended Sohag University Hospital Cath. Lab. for coronary angiography from the first of January 2018 till the end of December 2021. Demographic data, risk factors of coronary artery disease, different presentations, echocardiographic and coronary angiographic findings were analyzed and assessed. Results: More than half (56.2%) of patients with NVAF had CAD. The majority of NVAF patients with normal coronary angiography were in score 2. All 26 patients had single CAD >50%: stenosis with 4 in score 0, 8 in score 1, 7 in score 2, 5 in score 3 and 2 in score 4. One patient had 2VD and was in score 2. 10 patients had 3VD: 2 in score 0, 5 in score 1, 2 in score 2, and 1 in score 3 . Conclusion: More than half (56.2%) of the patients with NVAF had CAD based on coronary angiography. Single vessel CAD >50% was the most frequent lesion observed, meanwhile there was no correlation between the severity of the disease and CHA2DS2VASC score in NVAF patients.