Understanding comorbid metabolic dysfunctions in Alzheimer’s disease using the AD‐BXDs

Alzheimer’s disease (AD) is a neurogenerative disease characterized by cognitive deficits. Cognitive decline in AD is often accompanied and preceded by non‐cognitive comorbidities, including metabolic dysfunctions such as weight loss. Therefore, understanding how comorbid metabolic dysfunctions contribute to AD disease progression can provide useful insights into early disease risk detection and intervention.