Early detection of Alzheimer's disease subtypes in Amsterdam Dementia Cohort

Heterogeneity in the atrophy profile and clinical presentation of Alzheimer’s disease (AD) is well documented in literature. Defining tangible data‐driven subtypes and detecting these subtypes early in an individual is paramount to devising precise intervention strategies. In this study, we estimated distinct data‐driven AD subtypes and their corresponding atrophy timelines from cross‐sectional data and used it for predicting the subtypes of preclinical and prodromal patients.