Comparative Treatment Outcomes for idiopathic subglottic stenosis : 5-Year update

L A R Y n G O L O G Y of cases. Margin status was positive in 5/14 patients on frozen section and revised in 2 patients. The sensitivity of frozen sectioning in identifying the primary tumor was 48.3%. Intraoperative frozen section results were found to have a specificity of 100%. The ipsilateral tongue base was the most common location in 22/29 (75.9%), followed by the ipsilateral palatine tonsil 6/29 (20.7%) and bilateral base of tongue tumor 1/29 (3.4%) patients. In patients who had primary identified on final pathology, all who had a remote history of tonsillectomy (n=9) were found to have base of tongue cancer. Conclusion: This study demonstrated that the sensitivity of the identification of the primary tumor in unknown primary HPV+ SCC was <50%. Therefore, routine frozen tissue analysis for unknown primary HPV+ SCC may have low utility when considering additional operative time and cost frozen sections add.