Proteomic profiling of cognitive function in middle‐aged and elderly adults

Dementia is a pressing public health issue that affects 55 million adults worldwide. Some risk factors for cognitive decline and poor brain health appear to affect the blood brain barrier or cerebrovasculature. Therefore, it is plausible that circulating proteins may reflect causes and consequences of poor brain health. Identifying associated circulating proteins could help uncover important biological pathways in cognitive decline and dementia.