Characterization of a mouse model as a predictive tool for human Post‐Acute Sequelae of Covid‐19

While initial effects of Covid‐19 are concentrated in the respiratory system, numerous neurological symptoms and complications have been documented both during the acute disease course, as well as lingering symptoms following infection. Emerging reports have documented a multitude of transcriptional, proteomic, and homeostatic changes following acute infection. Here, we systematically evaluate a transgenic mouse model, a 5xFAD x hACE2, for its ability to recapitulate key underlying PASC‐pathologies.