Phlogacanthus cornutus: chemical profiles and antioxidant effects

Phlogacanthus cornutus is a rare species and the chemical profiles and the bioactivities of this plant are unknown. In present study, the chemical components of the acetone extract as well as the antioxidant activity of acetone extract and its fractions such as n-hexane, chloroform and ethyl acetate of P. cornutus were firstly reported. A total of 33 constituents were identify in the acetone extract of this plant using Gas Chromatography/Mass Spectrometry assay, in which trans-cinnamic acid (21.26%), neophytadiene (6.36%), linolenic acid (5.86%), dihydroagathic acid (5.71%), n-hexadecanoic acid (5.53%), phytol (4.14%) and cis-cinnamic acid (3.23%) were the major compounds. The acetone extract and its fractions such as n-hexane, chloroform and ethyl acetate of P. cornutus showed DPPH radical scavenging activity with IC50 value of 234.31, 185.95, 758.65 and 458.52 µg/mL respectively.