CLINICAL CASE OF A SEPTIC FORM OF YERSINIOSIS

The role of various viral and bacterial pathogens in vascular damage and the development of vasculitis is known. Yersiniosis is one of such infectious diseases that is associated with the damage of various organs and systems. Authors report the clinical case of a septic form of yersiniosis in a 16 y/o male patient with the development of generalized vasculitis with thrombus formation and organ disturbances of microcirculation. Based on the epidemiological history (the patient has visited Nepal), clinical and laboratory examination (severe intoxication, prolonged febrile fever with chills, flushing of the face and neck, conjunctivitis, scleritis, maculopapular rash with petechial elements, increased dyspnea, tachypnea, hypoxemia as a manifestation of edematous syndrome in the lungs and the development of hydrothorax, hypotension, oliguria and azotemia as a manifestation of toxic kidney, meningism; neutrophilia with a stab shift, thrombocytopenia, increased CRP, urea, creatinine, cytolysis syndrome, hypoproteinemia, hypoalbuminemia, hypoprothrombinemia, increased D-dimer levels , a decrease in the levels of protein C and S, an increase in the level of protein in the cerebrospinal fluid against the background of reactive pleocytosis; echo signs of thrombophlebitis of the left leg, X-ray picture of edematous-interstitial changes in both lungs, bilateral hydrothorax); serological study (increase in antibody titer to Y. enterocolitica in RPHA) diagnosed with yersiniosis, septic form, complicated by septic shock, DIC, acute respiratory distress syndrome, bilateral hydrothorax, III degree respiratory failure, acute kidney injury, thrombophlebitis superficial veins of the left leg, posterior tibial vein.