FOXO3 longevity genotype protects elderly men with late‐life hypertension from Alzheimer’s disease – Kuakini Honolulu Heart Program

While studies have found that mid‐life hypertension increases risk of Alzheimer’s disease (AD), the association of late‐life hypertension with AD is still unclear, FOXO3 genotype influences mortality risk from cardio‐metabolic diseases (CHD, diabetes, and hypertension). We hypothesize that FOXO3 genotype affects the risk that late‐life hypertension poses to development of AD.