Chemophotothermal therapy using Paclitaxel and gold nano star loaded temperature sensitive liposome for melanoma treatment

Melanoma is considered as one the deadliest tumors. There is a discovery of a rising trend of melanoma detection in developed countries. Nevertheless, early detection is currently most acknowledged method, and for effective treatment of latter melanoma, contemporary clinical treatment involving chemotherapy and photothermal therapy are often not effective in completely elimination of melanoma cell. Therefore, in this paper, we have proposed a prototype that combines chemotherapy and photothermal therapy. Temperature sensitive liposome is used as the carrier of medicine, carrying Paclitaxel and gold nano star. Paclitaxel loaded temperature sensitive liposome is prepared by film dispersion method. We have demonstrated that such prototype is biocompatible and biodegradable, possessing a promising future in assisting melanoma healing.