Validation of a fully automated lab developed test for plasma phospho‐tau 181 levels for Alzheimer’s disease diagnosis

The potential usefulness of plasma phosphorylated tau (pTau) measurements for identifying individuals likely to be on the Alzheimer’s disease (AD) continuum is evident from recent literature. Here we report the validation of an immunoassay for measurement of pTau181 in human plasma that will aid in the evaluation of Alzheimer’s pathology in cases presenting with mild cognitive impairment.