Chemistry and Pharmacological Exploration of Benzoxazole Derivatives

Benzoxazole is one of the most prominent heterocyclic structures and is found in an extensive range of biologically active compounds. It is one of the often occurring heterocyclic nitrogen-containing moieties that perform as the primary active elements of pharmaceutical compounds. It can be viewed as isosteres of the naturally occurring guanine and adenine nucleic bases since they interact effectively with the polymeric components of biological systems. A wide range of biological features, including analgesic, antibacterial, anti-inflammatory, anti-hyperglycemic, anticancer, antiviral, antifungal, antileishmanial, and antitubercular activities, they are significantly influenced by heterocyclic compounds with a benzoxazole nucleus.
Keywords: Benzoxazole, anticancer, antihyperglycemic, antibacterial, Caboxamycin, Pseudopteroxazole