PREGNANCY COMPLICATIONS AND MODE OF DELIVERY IN COVID-19 WOMEN PERFORMING DELIVERY IN THE DISTRICT CLINICAL HOSPITAL IN KHANTY-MANSIYSK

The aim of the study is to assess the frequency of pregnancy complications and the mode of delivery in COVID-19 women performing delivery in the district clinical hospital in the city of Khanty-Mansiysk. 
Materials and Methods. The authors retrospectively analyzed 148 medical histories of COVID-19 women, who delivered in Khanty-Mansiysk perinatal center. All patient medical records were divided into 4 subgroups depending on the delivery term, and 3 subgroups depending on the disease severity. Statistical analysis was carried out using analytics software packages Statistica 10 (USA) and StatTech v. 2.8.4 (Stattech, Russia, 2020). Given group heterogeneity, non-parametric statistical methods were used to calculate quantitative and qualitative parameters. Fisher Z transformation and the Mann-Whitney test were used to compare the parameters. Differences were considered statistically significant at p≤0.05, CI 95 %. 
Results. In all subgroups the most common pregnancy complication in COVID-19 patients was anemia. It was observed in 50.8 % to 74.3 % of cases. The maximum incidence of moderate preeclampsia was 2.7 %, that is below the average population value. Most placental abnormalities were detected in subgroups of women who gave birth during 3rd and 4th waves of COVID-19 (37.1 % and 33.8 % respectively). In the same subgroups, fetal growth retardation (28.6 % and 32.3 %), statistically significant increase in the proportion of preterm births (34.3 % and 38.5 %) and transfers to the neonatal intensive care unit (28.6 % and 26.2 %) were often observed.