Characterizing progressive speech changes in prodromal‐to‐mild Alzheimer’s disease using natural language processing

Novel automated tools for analyzing speech and language may provide new insights into Alzheimer’s disease (AD). Although speech and language changes occur in AD and other neurodegenerative diseases, current clinical assessments to monitor these symptoms can be burdensome and may have limited sensitivity. Through analyses of open‐ended naturalistic speech collected from a standardized clinical interview, we developed a novel measure to characterize progressive speech changes in AD.