Dyadic patterns of subjective cognitive reports as predictors of incident dementia

Subjective cognitive decline (SCD), in the absence of impaired clinical testing, may be a clinical indicator of early Alzheimer’s disease (AD) and other dementias. However, not all individuals with SCD have cognitive decline. Corroboration of decline by an informant (i.e., close friend or family member) is one feature of SCD thought to increase the likelihood of preclinical AD. Few studies have examined whether different patterns of SCD in individuals and their informants are related to risk of dementia over time.