Meningioma: Is apparent diffusion coefficient value of any importance? A study from the tertiary care center



Meningiomas are one of the most common intracranial tumors accounting for 14–20% of all intracranial tumors. Diffusion-weighted imaging (DWI) along with the calculation of apparent diffusion coefficient (ADC) is a novel, non-invasive, and reliable technique of choice for the pre-operative assessment and the treatment planning of different types of meningiomas. Our study aimed to correlate the ADC values of meningiomas with their histopathological grade.



We studied 21 patients with meningioma. These were initially diagnosed on imaging and confirmed on histopathology. We calculated the normalized ADC (NADC) values from the DWI of their lesion. NADC values and atypical morphological features were utilized to type the meningiomas as typical or atypical. These findings were correlated with histopathological reports of grading of meningioma.



There was no significant correlation between the grades of meningioma and the ADC values. The normalized ADC values varied from 0.14 to 1.37 × 10−3 mm2/s for Gr I meningioma in our series and most of our cases fell in this category of meningioma. We had a solitary case of Gr-II meningioma and the ADC value for this lesion was 1.26 × 10−3 mm2/s.



Meningiomas are a common group of tumors in the brain with a quest to characterize the grades preoperatively on imaging. The NADC is a better method as compared to plain ADC values for this purpose. In our series, we did not find any correlation of NADC on pre-operative imaging to the grades of tumors.
