Tau Pathology induces Whole‐Brain Subcritical Brain Dynamics across the spectrum of Alzheimer’s Disease

Cognitive dysfunction in Alzheimer’s Disease (AD) is caused by dysfunctional brain region interactions. Although functional connectivity alterations in AD have been described in several studies, their associations to tau pathology have not been completely understood. Using whole‐brain network modeling we can mechanistically associate the functional impact of tau on brain function in silico.