Standardized preprocessed derivatives for the Comprehensive Assessment of Neurodegeneration and Dementia (COMPASS‐ND) Study

The Comprehensive Assessment of Neurodegeneration and Dementia (COMPASS‐ND) cohort of the pan‐Canadian Consortium on Neurodegeneration in Aging (CCNA) provides imaging on participants following a standardized protocol. This imaging contribution to deep phenotyping is done to study the full spectrum of age‐related dementias in more than 1,100 individuals (50‐90y) with subjective or mild cognitive impairment, Alzheimer’s disease, other dementias, or otherwise cognitively unimpaired. To accelerate discovery, we propose to release biomarkers extracted from these acquisitions. Here we present preliminary (N=385, AD=39) preprocessing methods, quality control, and available derivatives of the resting‐state functional (rsfMRI), diffusion weighted (DWI), and structural magnetic resonance images.