CHEMICAL CONSTITUENTS AND ANTIBACTERIAL PROPERTIES OF KITAGAWIA BAICALENSIS (REDOW. EX WILLD.) PIMENOV ESSENTIAL OILS

Kitagawia baicalensis (Redow. ex Willd.) Pimenov (Umbelliferae) is a perennial monocarpic plant with Siberian-Mongolian type of habitats. Decoction of flowers and roots has been used in Tibetan medicine for intoxication and as diuretic agent to treat edema. The essential oils of the aerial part of K. baicalensis growing within the territory of the Republic of Buryatia were obtained by steam distillation method. The isolated essential oils were yellow oily liquids, lighter than water, with characteristic pleasant odour. The qualitative composition and quantitative content of the components of essential oils were determined by GC/MS. 26 compounds with aromatic, mono- and sesquiterpenoid structures were identified in the composition of essential oils. The main components of the essential oils of the aerial part of the Kitagawia baicalensis from Buryatia were limonene (34.40%), β-myrcene (21.10%), γ-terpinene (12.60%), β-elemen (5.70%), sabinene (5.30%), germacren B (3.20%) and germacrene D (3.10%). Monoterpenoids (83.00%) predominated in general composition of essential oils. The content of compounds with sesquiterpenoid structure was 14.70%. The group of aromatic compounds was represented only by p-cymene (2.30%). Bactericidal and bacteriostatic activities of essential oils against Bacillus cereus, Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica, Aspergillus niger, Candida albicans were determined in this paper. The most pronounced antibacterial effect of essential oils was found against Streptococcus pyogenes (1 : 64 dilution).