Non-Small Cell Lung Cancer Metastases to Breast, Colon and Skin: A Case Report

Bronchogenic carcinoma is a leading cause of cancer mortality worldwide. Of lung cancer cases overall, 50% have metastasis at presentation, mostly to the brain, bone, liver, the adrenal glands ,thoracic cavity and non-regional lymph nodes .This case report presents a female patient with three rare sites of lung cancer metastasis: breast, colon, and skin. Her initial presentation was a several-month history of a mass in the left breast and in the upper abdominal wall, dyspepsia, weight loss, and intermittent per rectal bleeding. Diagnosis of this case was difficult because of the challenge to differentiate between primary breast cancer and metastasis. However, the diagnosis was made by the interpretation of images and immunohistochemistry.