Abstract IA013: Early-onset colorectal cancer: Emerging risk factors and early detection


 Early-onset colorectal cancer (CRC) is increasing in the United States and globally. Compared to CRC diagnosed at older ages, patients with early-onset CRC experienced significant diagnostic delays, with tumors of advanced clinicopathological features and unknown etiology. While screening recommendations have been recently lowered to age 45 in the United States, about half of early-onset CRC cases are diagnosed before age 45, thus will not be detected via screening. This presentation will review emerging risk factors of early-onset CRC throughout the life course, as well as clinical signs and symptoms associated with early-onset CRC.
 Citation Format: Yin Cao. Early-onset colorectal cancer: Emerging risk factors and early detection [abstract]. In: Proceedings of the AACR Special Conference on Colorectal Cancer; 2022 Oct 1-4; Portland, OR. Philadelphia (PA): AACR; Cancer Res 2022;82(23 Suppl_1):Abstract nr IA013.