Mechanisms Mediating the Anti‐inflammatory Effects of Eicosapentaenoic Acid in the APPswePS1dE9 Alzheimer's Mouse Model

Alzheimer’s disease (AD) is a progressive, neurodegenerative disorder characterized by amyloid‐beta (Aβ) plaques, which may be exacerbated by obesity. We previously reported anti‐obesity and anti‐inflammatory effects of eicosapentaenoic acid (EPA), in diet‐induced obese mice. Therefore, the objective of this research is to determine whether EPA also protects against AD‐associated Aβ deposition.