Isolation, Investigation and Antimicrobial activity of a dihydrochalcone from the leaves of the Catharanthus roseus L.

Dihyrochalcone is subclass of Flavonoids which are polyphenolic compounds that are widely found in the plant kingdom as secondary metabolites, they possess a variety of biological activities. The purpose of this study was to isolate and identify the Flavonoids  from the leaves of Catharanthus roseus  and testing it for anti-microbial activity. The plant was collected from Omdurman area, the powder was prepared from leaves and some chromatographic methods were applied to isolate compound I. The structures of this compound was elucidated based on spectroscopic methods as: IR,UV,MS and 1HNMR spectroscopy, and also the microbial activity of Compound 1 gave activity against all organisms that were tested. The results of this study have provided scientific validity for use of this plant in traditional medicine to treat infectious diseases.