A 2‐year Choral Singing intervention with community‐dwelling older adults at risk of cognitive decline to improve bio‐psychological outcomes: An open‐label Randomized Controlled Trial

Few randomized controlled trials (RCTs) have investigated the effects of choral singing (CS) on community‐dwelling older adults at‐risk of cognitive decline. Specifically, scarce literature exists on the effects of CS on affective symptoms and other bio‐psychological risk factors of cognitive decline, including low‐grade inflammation and perceived stress. Extant interventional studies on CS lack robust RCT design incorporating an active control arm controlling for active components which are not intervention‐specific. Addressing these gaps in knowledge, we initiated the CS‐RCT and hypothesized that a 2‐year CS intervention with older adults at risk of cognitive decline will improve affective, i.e., depressive and anxiety, symptoms, high‐sensitivity c‐reactive protein (hs‐CRP) levels, and perceived stress.