Clinical validation of the Virtual Reality Functional Capacity Assessment Test – Short List (VRFCAT‐SLx) for assessment of iADL functioning in early symptomatic Dementia: Sensitivity to cognitive and functional change over time

Assessment of functional capacity is critical to the diagnosis and monitoring of Alzheimer’s disease and related dementias. The VRFCAT (Keefe et al., 2016) is a performance‐based assessment of iADL functioning that is completed on a tablet. Previous work on the VRFCAT has demonstrated correlations with clinical endpoints and sensitivity to cognitive impairment in individuals with subjective cognitive decline (SCD) and schizophrenia. To facilitate use longitudinally and in more impaired patient groups, the VRFCAT “short list” (VRFCAT‐SLx) was recently developed to reduce task complexity and length (see Atkins et al. AAIC submission). The aim of the present work was to characterize the VRFCAT‐SLx’s sensitivity to longitudinal clinical changes in subjects with early symptomatic MCI/AD dementia