Dual‐tracer assessment of CBF and early amyloid uptake of Alzheimer’s disease using 15O‐water and amyloid PET

Reduced CBF and amyloid update measured by PET imaging have been reported among Alzheimer’s disease (AD) patients. Evidence suggested that early amyloid update may reflect the underlying CBF information. In this pilot study, we aimed to compare whether early uptake amyloid PET images can be used to estimate CBF, by comparing them with gold‐standard 15O‐water PET CBF images.