A Dosimetric Analysis of Modified Volumetric Modulated Arc Therapy for Bone Marrow Sparing Radiotherapy in Cervical Cancer-An alternative Approach to Conventional VMAT

Cervical cancer remains a predominant cause of cancer incidence and mortality among women globally, particularly in developing nations (Arbyn et al., 2022). In comparison to radiation therapy alone, the use of combination therapeutic interventions, such as concurrent chemotherapy and radiation therapy, is advised for better tumour control and progression-free survival (Morris et al., 1999; Peters et al., 2000; Green et al., 2001). Numerous investigations have found that while the intended dose is delivered to the tumour using conventional radiation techniques, the prescription tumour dose (Lukka et al., 2002; Mell et al., 2006) irradiates a greater amount of bone marrow due to technical limitations of the treatment Abstract