Bilateral breast multiple myeloma: a case report

Multiple myeloma (MM) is a malignant disorder characterised by excessive proliferation of single clonal plasma cells derived from B cells in the bone marrow with increased formation of monoclonal immunoglobulins.1 Multiple myeloma may involve extramedullary organs or soft tissues (extramedullary plasmacytoma), commonly in the upper aerodigestive tract with a predilection for the head and neck.1 Breast plasmacytoma is very rare. We present a case of MM with extensive extramedullary involvement including bilateral breasts, and mainly focus on the imaging features of breast plasmacytoma across multi-modalities. Hong Kong Med J 2022;28:488–90 https://doi.org/10.12809/hkmj219555