The eye as a biomarker for Alzheimer’s disease: oculomotor behaviours yield a novel digital biomarker for preclinical risk detection

They eyes seem to hold a key to unveil early manifestations of Alzheimer’s disease (AD) pathology beyond retinal analysis. We have recently confirmed that eye‐tracking (ET) metrics recorded during performance on memory tasks can identify early and subtle changes in individuals at risk of or with AD dementia. There is a need for more robust and automatic classification methods that can provide affordable digital biomarker solutions for the preclinical detection of AD. This was the aim of this study.