Diagnosis and management of supine and nocturnal hypertension in orthostatic hypotension: a review



The prevalence of supine and nocturnal hypertension (S-N-HT) is high among patients with orthostatic hypotension (OH), especially in those who have a neurogenic aetiology. The evidence suggests that S-N-HT exacerbates OH, although it is unclear whether pharmacologic treatment of S-N-HT will improve OH. S-N-HT has also been associated with target organ damage. Therefore, assessment and management of S-N-HT should be an integral part of managing OH, but it is often overlooked in clinical practice. The present review seeks to provide comprehensive information on S-N-HT, with a particular focus on pathophysiology, diagnostic evaluation, and management. The aim is to provide a practical guide for managing S-N-HT.
