Microwave-Assisted, [Bmim]PF6-Catalyzed Synthesis of Benzoxazoles under Solvent-free Conditions



An efficient and green strategy for the synthesis of 2-arylbenzoxazoles catalyzed by [Bmim]PF6 ionic liquid has been investigated via the condensation of o-aminophenol with aldehydes. The microwave-assisted synthesis features some advantages such as good yield of products, broad substrate scope, simple product purification, and absence of metal catalyst and solvent. Furthermore, the synthesis could be conveniently expanded to a gram scale.
