Impacts of Aerobic Capacity, Liver Function, and Metabolism on Brain Health

Aerobic capacity (VO2 max) strongly influences biological functions including both liver and brain function. Low aerobic capacity has far reaching impacts with both increased risk of non‐alcoholic fatty liver disease (NAFLD) and Alzheimer’s disease (AD). Previous work has shown that poor liver function was associated with decreased cognitive function and increased risk of AD. In addition, diet and lipid metabolism play a critical role in brain health, however, the full relationship between these factors and AD risk needs to be elucidated.