LISCH NODULES AN OCCULAR MANIFESTATION IN A CASE OF NEUROFIBROMATOSIS

Neurobromatosis (NF) is a multisystem disorder caused by a genetic mutation on chromosome 17. Neurobromatosis 1
is the form with the most characteristic ocular manifestations. Lisch Nodules of the iris are the well-known diagnostic
criteria for the disease. Lisch nodules are usually seen at in young age. Our patient is an 8 years old female who presented with pain and swelling
over the left chest and who showed features of neurobromatosis like cafe au lait spots and lisch nodules. Similar lesions were present in her
mother. Lisch nodules are pathognomic of NF1 and should be differentiated from iris nevi observed in the general population. This disease is
associated with increased morbidity and mortality. With an improved understanding of the disease and advancement in management, we can
prevent complications.