The association of accelerometer‐measured physical activity, white matter hyperintensity volume, and cognition in normal aging

White matter hyperintensities (WMH) are an indicator of small vessel cerebrovascular disease, which increases the risk of developing Alzheimer’s disease and related dementia (ADRD). Moderate to vigorous intensity physical activity (MVPA), can help maintain brain structure, function, and cognition in aging. However, the mechanisms by which MVPA may preserve cerebrovascular health remain understudied. To help elucidate the cerebrovascular mechanisms by which MVPA preserves cognition, we examined associations of MVPA and WMH volume, MRI markers of neurodegeneration, and cognition.