Dual tasking paradigm in clinical stages of early Alzheimer’s disease

In Alzheimer’s disease (AD) both motor and cognitive domains are impaired [1‐2]. However, these domains are usually assessed independently and even when performing dual‐task (DT) paradigms, the cognitive‐motor interaction (CMI) is not taken into account, which may lead to misinterpretation of the patient’s global state. To date, there are no precise markers to detect subtle signs of pre‐clinical neurodegeneration or to accurately monitor disease progression.