Participant FIRST: Improving Communication With and Support For Participants in Trials that End Early

In 2019, multiple AD/ADRD trials ended earlier than planned. Participants subsequently stepped forward explaining they first learned their trial ended via news coverage, rather than from a site investigator or research staff. As a result, the issue of participant notification—and the emotional impact of being in a trial that stops early—gained attention. This led to calls to identify better ways to communicate with and support participants after trials end early.