Harmonization of neuropathology measures and characterization of neuropathological burden across population‐based autopsy samples

Most autopsy samples are based on clinical cohorts or case series; the distribution of neuropathologies may be biased in these samples compared to the general population. A small number of population‐based neuropathology cohorts address these concerns but are often limited by small sample sizes and restrictions to specific geographic locations or groups. Harmonization would allow comparisons across settings and increases in precision of estimates.