White Matter Hyperintensity and PET‐Based Amyloid Load Correlations: A Meta‐Analysis

White matter hyperintensities (WMHs) are prevalent vascular pathologies that often co‐occur with amyloid plaque deposition in Alzheimer’s disease (AD). Previous research has shown that antemortem WMHs correlate well with post‐mortem findings of cerebral amyloid angiopathy (CAA). PET‐amyloid imaging is widely used to assess in‐vivo amyloid load, however the extent to which CAA‐binding of amyloid tracers contributes to global measures of amyloid load is unclear. The aim of this meta‐analysis was to determine the strength of the correlation between amyloid load and WMHs in AD subjects.