Age‐related PSA testing for prostate cancer: NICE recommendation 1.6.3

The institutional ethically approved Imperial/RM Partners Rapid Access Prostate Imaging and Diagnosis Online (RAPIDOnline) project now has 5 years of referral and outcome data from approximately 4100 patients. All were referred under the UK 2-week wait cancer referral pathway, when the referral criteria were PSA ≥3 ng/mL for men aged 50–69 years and ≥4 ng/mL for those aged 70–79 years or those with an abnormal rectal examination (DRE). All patients underwent multiparametric MRI (T2, diffusionweighted and dynamic contrast-enhanced imaging) and, if required (Prostate Imaging Reporting and Data System [PIRADS] score/Likert score ≥3/5), a transperineal targeted biopsy with systematic sampling.