Raindrop animation: Visualizing change in longitudinal biomarker data

The Knight ADRC has collected fluid biomarker data from some participants over more than >15 years, affording a unique opportunity to explore trends in the progression of Alzheimer disease biomarkers. Evaluation of intra‐individual change provides a uniquely powerful approach to understanding the development of Alzheimer disease pathophysiology, notably non‐linear changes in biomarkers. To facilitate understanding of longitudinal analyses, an approach was developed to visualize longitudinal change in biomarkers.