Regional Differences of the Impact of Healthy Aging on Myeloarchitecture at 7T

Cortical gray matter (cGM) loss in healthy aging has been well documented by volumetric MRI. Less well known though is if this age‐related cGM loss is layer‐specific or diffuse. Benefiting from the higher resolution at 7T and the close relationship between cortical cyto‐ and myeloarchitecture (1) this project used a newly developed technique for the differentiation between heavily (layers IV‐VI) and sparsely (layers I‐III) myelinated cortical layers to investigate this question.