Midlife and current physical activity is associated with functional brain connectivity in older age

Previous studies have shown a physically active lifestyle in both midlife and later life to benefit cognition and brain health in older age. However, exploring the influence of physical activity engagement on functional brain connectivity is needed to fully understand the neural mechanism underlying the effect of physical engagement. Additionally, in order to give lifestyle advice to different age groups, it is important to understand the unique contributions of physical activity at different life stages, which has rarely been examined.