Cannabinoids as a potent therapeutic target for Alzheimer’s disease

The NMDA receptor plays a central role in the CNS excitatory neurotransmission, being also a therapeutic target to combat AD. Receptor function deregulation is, at least in part, responsible for the progression of the disease. In this regard it would be interesting to discover membrane proteins capable of interacting with NMDA receptors, and being able to modulate their function to slow the onset of symptoms and the progressive neurodegeneration.