Enhanced Machine Learning Classification of Cognitive Impairment with Multimodal Digital Biomarkers

Linus Health’s DCTclock™ is an FDA‐listed cognitive assessment solution capable of detecting early signs of cognitive decline. DCTclock digitizes the long‐standing pen‐and‐paper Clock Drawing Test (CDT) and captures a wide variety of cognitive and motor metrics during the entire drawing process. Multiple studies have validated the DCTclock’s ability to detect early cognitive impairment and improve on existing assessment methods (e.g., Souillard‐Mandar et al. 2015 & 2021, Rentz et al. 2021). Linus subsequently developed the Digital Clock and Recall (DCR™) assessment, which incorporates voice and delayed verbal recall alongside the DCTclock. The analysis below evaluated the added benefit of the DCR and the relationship between voice analytics and diagnosis.