Concerted alterations of functional connectivity and WM integrity in relationship to early amyloid deposition

Early amyloid deposition results in functional and structural brain alterations in predementia stages of Alzheimer's disease (AD). However, how early functional and structural brain changes are related to each other remains unclear. Investigating the simultaneous disruptions of functional‐structural brain features within individuals in relation to amyloid deposition may increase our understanding of the neuropathological processes underlying AD.