Sex differences in CSF biomarkers profile of accelerated biological aging individuals at risk of Alzheimer’s disease

Prevalence of Alzheimer’s disease (AD) is higher in women than in men; however, underlying biological mechanisms remain unknown. Being aging the major risk factor for AD, sex dimorphism in biological aging could explain sex‐specific patterns of disease manifestation across the Alzheimer’s continuum. This study aimed to explore whether there are sex‐specific differences in specific biological pathways among individuals at accelerated or decelerated biological aging.