Prevalence and Associations of Frailty in Preclinical Alzheimer’s Disease

The prevalence of frailty in asymptomatic Alzheimer’s disease is not clear. In this cohort screened for a preclinical Alzheimer’s disease clinical trial, we aimed to compare the prevalence of frailty between participants with and without elevated amyloid as determined by PET and determine if frailty influences the relationship between amyloid and cognition.