The applications of AFM in the study of cell, molecule, tissue level to understand the structure and function of organisms

To have a more detailed understanding of the structural characteristics, information transmission and other aspects of an organism, it can be started with the three most basic levels of cells, molecules and tissues. Cells are the most basic unit that constitutes an organism. Their structure determines its function. Observing the structure of cells is of great help to understand the function of an organism. Every strange biological phenomenon is the result of intermolecular interaction. Studying the existence significance of each molecule in a biological process can more thoroughly understand the details of the biological process. Tissue is a structure composed of a series of cells and biological macromolecules. The study of tissues can directly reflect the principle of the operation of birth objects. With its high resolution, AFM is widely used in these three levels of research. This article will introduce the screening of cancer cells by AFM at the cell level, the determination of protein-DNA/RNA interaction properties in molecular interactions and the characterization of ECM in lung tissue at the tissue level.