Antimicrobial and Antioxidant Study of Some Newly
Synthesized Chalcones and Cyclohexenone Derivatives

Chalcones and cyclohexenone derivatives obtained from various substituted aldehydes and substituted
acetophenones are described. Chalcones were obtained by the Claisen-Schmidt condensation reaction
of aldehydes with substituted acetophenones. Base catalyzed cyclocondensation of ethyl acetoacetate
to chalcones under microwave irradiation leads to the formation of cyclohexenone derivatives. The
prepared compounds are characterized by IR, 1H NMR and 13C NMR spectral methods. These are
screened for their antimicrobial activity against Staphylococcus aureus, Escherichia coli, Aspergillus
niger, Aspergillus flavus and also, for their antioxidant properties.