504 ACUTE HEART DISFUNCTION IN PATIENT WITH PACEMAKER, ATRIAL FIBRILLATION AND OLD MYOCARDIAL INFARCTION: WHAT IS THE REASON?


 Patient (pt) 78 years old, ex smoker, with hypertension, dyslipidemia, iperuricemia and overweight. Myocardial inferior infarction with mechanical rivascularization and implant of drug eluting stent on right coronary artery in 2012. Residual ejection fraction of 47% with inferior hypocinesia. Pacemaker DDD implant for 2nd degree atrioventricular block in 2013. Atrial fibrillation from July 2021. Acute nocturnal heart failure with hypoxiemia (PO2 76%) and necessity of non invasive ventilation in November 2021 without worsening of coronary tree at coronarography and echocardiografic finding of EF 47% with inferior and posterior hypocinesia. Troponin I hs 53.6 pg/ml BNP 378 ng/ml. None relevant arrhytmias at pacemaker control. After hospital admission pt done polisonnography with finding of severe obstructive nocturnal apneas and need of CPAP (continous positive airways pressure).
 
 
 in literature obstructive sleep apnea syndrome (OSAS) can cause heart failure, cardiac ischemic disease and hypertension. In this case a long obstructive apnea could have caused severe desaturation with hypoxiemia and then an acute episode of heart failure.
