Comparative Study of Serum Lipid Profile in Pre-Eclampsia and Normal Pregnancy

Background: Pre-eclampsia is an important cause of fetal and maternal morbidity and mortality worldwide. It is therefore, important to study the lipid profile and risk factors for prevention, management and better prognosis of the disease. Method & Materials: This study was a case control study conducted in the Department of Obstetrics and Gynaecology, Tezpur Medical College and Hospital, Tezpur. A total of 100 (one hundred) were selected, out of which 50 (fifty) normotensive pregnant women served as a control and 50 (fifty) Pre-eclampsia women constituted the study group. Besides baseline routine investigations, estimation of Serum lipid profile was done by collecting blood samples from antecubital vein of every case and control following a fast of 12-14 hours and collected in plain vials and were analysed at department of Biochemistry, Tezpur Medical College and Hospital, Tezpur. Results: The preeclampsia group had a significant rise in Triglyceride (TG), total cholesterol, LDL-C levels and decreased HDL-C levels as compared to the control group. Conclusion: Abnormal lipid profile results during pregnant women plays an important role in development of pre-eclampsia.