Crop Filling: artefact removal for real‐world clinical neuroimaging data

The use of standard clinical neuroimaging data for quantitative research is often precluded by imaging artefacts caused by real‐world limitations. For example, partial coverage (cropping) of T1‐weighted MRI scans can occur when a memory clinic prioritises visual ratings on T2‐weighted MRI, and so the T1 scan field‐of‐view is reduced to minimise the overall acquisition time. This study investigated cropping‐induced biases in T1‐MRI volumetric measurements and proposed and validated a solution.