p75NTR modulation counteracts alterations in neuronal and glial activity‐dependent profiles of gene co‐expression networks in tauopathy mice

P75NTR is a key mediator in the regulation of neuronal plasticity, and modulation of its signaling prevents synaptic dysfunction in Tau.P301S mice, as measured by long‐term potentiation (LTP). Since LTP alters gene expression programs and results in transient post‐translational modifications at synapses, we asked whether tauopathy‐associated alterations in gene co‐expression, in response to stimulation, can be counteracted by p75NTR modulation.