2244. Prescribing Patterns of Urinary Tract Infections in Patients Discharged from the Emergency Department


 
 
 Urinary tract infections (UTIs) are one of the most common infections in the emergency department (ED). The risk of treatment failure and readmissions to the ED may be increased with inappropriate antibiotic regimens. The purpose of this project is to determine the proportion of patients receiving guideline-based therapy (GBT) for UTI discharged from the ED.
 
 
 
 Single-center, retrospective cohort study of adult patients diagnosed with an UTI or pyelonephritis from July 1-December 31, 2020. The primary outcome was to describe the proportion of patients discharged from the ED who received GBT for UTI. Secondary outcomes were to define the proportion of patients readmitted within 30 days, describe the reason for readmission, and compare 30-day readmission rates in patients who received GBT versus non-GBT.
 
 
 
 Of 370 patients screened, 68 were excluded primarily for inpatient admission. Of the 302 patients included, 172 (57%) received GBT and 130 (43%) received non-GBT with no significant difference in Charlson Comorbidity Index (p= 0.48) between groups. Fifty two of 302 patients (17.2%) were readmitted within 30 days; 31 (60%) from GBT and 21 (40%) from non-GBT (p=0.632). Of the 52 readmissions, 14 (26.9%) were related to the UTI and returned for either persistent symptoms (11 patients) or development of sepsis (3 patients).
 Readmissions related to persistence of UTI and development of sepsis were not significantly different between GBT and non-GBT, 9 patients and 5 patients respectively (p=0.92).
 
 
 
 The majority of prescribed antibiotic therapy did conform to GBT for UTI. However, 30-day readmission rates were not significantly different between groups.
 
 
 
 All Authors: No reported disclosures.
