Cross‐sectional and longitudinal comparison of 18F‐MK6240 and 18F‐Flortaucipir in populations matched for centiloid, age and MMSE

Longitudinal tau quantification may provide a useful outcome measure in disease‐specific therapeutic trials. Different tau PET tracers may have different sensitivity to longitudinal changes, but without a head‐to‐head comparison, equating results from different cohorts using different tracers can be biased. In this study, we aim to minimise this bias by matching participants in two cohorts imaged using 18F‐MK6240 and 18F‐Flortaucipir (FTP).