From FINGER to MET‐FINGER: metformin and lifestyle intervention for multimodal precision prevention of dementia

The positive results of the landmark Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability ‐ FINGER, 2‐year lifestyle‐based intervention and up to 11 years follow‐up ‐, followed by the Multimodal Preventive Trial for Alzheimer’s Disease ‐ MIND‐ADmini, 6‐month lifestyle‐based + medical food, up to 1‐year follow‐up ‐, provided the foundation to advance multimodal trials for dementia prevention within the World‐Wide FINGERS (WW‐FINGERS) network. Innovative trials should involve tailored approaches, combining non‐pharmacological and pharmacological interventions, to optimize interventions´ adherence and efficacy.