Improving the effectiveness of vaccination against viral and bacterial pathogens through micronutrient supplementation

Deficiency of certain micronutrients interferes with the functioning of acquired immunity, which may negatively affect the efficacy and safety of vaccinations. The results of clinical and epidemiological studies have shown that micronutrient supplementation before vaccination increases its efficacy (antibody titers against viral/bacterial pathogens) and safety (prevention of malaise, reduction of disease severity and mortality in case of post-vaccination infection). The aim of the study was to analyze the currently available studies on the relationship between micronutrient status and the results of vaccination against bacteria and viruses. Conclusion. Micronutrient supplementation contributes to the formation of adequate immunity after vaccination and increases the safety of vaccination. Vitamin-mineral complexes represent a cost-effective method to reduce the risks of vaccination in patients with polyhypovitaminosis.