An ELOVL2 based epigenetic clock for forensic age prediction: a systematic review

Review question / Objective: To develop an easy, robust and improved blood-based age prediction model using ELOVL2 promoter methylation data. Eligibility criteria: All studies with the aim of understanding the relationship between the ELOVL2 methylation levels and age written in English language, carried out in humans and providing a publicly available dataset will be included in the systematic review. Articles that did not include original research (e.g., review, opinion article or conference abstract) and for which methylation analysis will be carried out using a technology different from the pyrosequencing in tissues different form blood will be excluded from further analyses.