Predictive Accuracy of Inpatient Cognitive Screening for Correctly Classifying Mild Cognitive Impairment at 4 Months Using A Full Neurocognitive Battery in Acute Coronary Syndrome

D is a leading contributor to the global burden of disease due to progressive and unrelenting deterioration of the capacity of an individual to live independently. Vascular etiology is the second most common cause of dementia1 and cardiovascular disease (CVD) results in faster decline.2 Mild cognitive impairment (MCI), which may indicate early dementia, occurs frequently in acute coronary syndrome (ACS) patients.3 Prevalence rates vary widely (9-85%), depending on timing and assessment method used. A recent report indicated 63% had MCI on screening4 4-wk post-ACS. Data based on full neurocognitive assessment when recovery has progressed (4-mo postACS) are required for confirmation and to inform inpatient screening that reliably predicts MCI. Early detection of MCI enables timely intervention to potentially slow the progression of MCI to dementia and enable customizing of education and support.