Study on the Synthesis and Antibacterial Activity of Cobalt-Metal Organic Framework

Hydrogen peroxide (H2O2) has been widely used in the treatment of antimicrobial infections, but high doses of H2O2 can cause damage to normal tissues. Avoiding the use of high doses of H2O2 as well as being effective against multidrug-resistant bacteria, nanomaterials with peroxidase-like properties have been developed as a new class of antimicrobial agents. Here, we have synthesized Co-TCPP(Fe)(Co-MOF), a metal-organic framework material with a laminar folded structure and a heterogeneous surface morphology, using a solvothermal method, which exhibits good bactericidal activity against Pseudomonas aeruginosa with the help of low concentrations of H2O2.