Overestimation of performance after a memory task in cognitively unimpaired individuals is related to lower cortical thickness in Alzheimer’s disease vulnerable regions and to executive decline, particularly in men.

Low awareness of cognitive decline is a common feature in Alzheimer’s disease (AD) dementia, and it relates to higher risk of progression in individuals with Mild Cognitive Impairment. Previous research suggests that, in cognitively unimpaired individuals, it has prognostic value and is related to AD biomarkers. We aimed at exploring the associations between the ability to judge performance after a memory task and demographic, clinical (cognitive complaints), structural neuroimaging, cognitive and amyloid status variables in cognitively unimpaired individuals.