Associations Between Plasma, Imaging, Cerebrospinal Fluid Biomarkers and Naturalistic Driving Behaviors, Cognitive Tests Among Cognitively Normal Persons

Previous work indicates that imaging and cerebrospinal fluid (CSF) amyloid and tau biomarkers are associated with driving behaviors, and that driving behaviors can be used to identify preclinical Alzheimer’s disease (AD). Along with traditional biomarkers, we examined the extent to which newer plasma and CSF biomarker are related to driving and cognitive metrics among cognitively normal older drivers.