The Predictive Power of Cellular Homeostasis Models Illustrated with a Study of the Gardos Effect

Alexey Vereninov and collaborators pioneered the application of mathematical models of cellular homeostasis with ground-breaking contributions to the understanding of the mechanisms behind the dynamics of homeostatic changes in a variety of different cell types. As part of an issue dedicated to Vereninov’s memory, I thought that an example of the predictive potential of such models would be a fitting tribute to his work and achievements. The “Gardos effect” is the example chosen from our modelling experience.