Motoric Cognitive Risk Syndrome and Cognition: The Influence of Depression

Motoric Cognitive Risk (MCR) syndrome is a practical tool used to identify independent people at risk of developing dementia. Although mood disorders and MCR relates, whether depression changes the association of MCR with cognition remains uncertain. We estimated the associations of MCR with cognitive performance and impairment in people aged ≥50 years and examined whether depression modifies the relationship between these conditions.