Incentives to increase willingness to undergo research lumbar puncture

Alzheimer’s disease (AD) research increasingly relies on biomarker testing to understand longitudinal biological contributions to clinical disease progression. The collection of cerebrospinal fluid (CSF) through a lumbar puncture (LP) is an efficient method to obtain reliable AD biomarkers; however, most people are unwilling to participate in the procedure for research. This study aimed to understand what incentives could be offered to increase the propensity for people to consider a research LP.