2,5-Dimethoxy-p-cymene
# 2,5-Dimethoxy-p-cymene

2,5-Dimethoxy-p-cymene, or thymohydroquinone dimethyl ether, is a phytochemical found in the essential oils of plants within the family Asteraceae. These essential oils, which contain the compound as a major component of the oil, have antifungal, antibacterial, and insecticidal properties.

## Natural occurrence

2,5-Dimethoxy-p-cymene occurs in a variety of different plants' essential oils. Examples include:

* Ayapana triplinervis (92.8%)
* Apium leptophyllum (50.7 to 80.24%)
* Cyathocline purpurea (57.4%)
* Arnica montana (32.6%)
* Laggera crispata (32.2%)
* Blumea perrottetiana (30.0%)
* Eupatorium capillifolium (20.8%)
* Sphaeranthus indicus (18.2%)
* Limbarda crithmoides (16.4)
* Bubonium imbricatum (16.2%)

## Chemical synthesis

2,5-Dimethoxy-p-cymene can be synthesized from carvacrol by aromatic halogenation followed by nucleophilic substitution with sodium methoxide and Williamson ether synthesis using methyl iodide.

