E-55888
# E-55888

E-55888 is a drug developed by Esteve, which acts as a potent and selective full agonist at the $5HT_7$ serotonin receptor, and is used for investigating the role of $5-HT_7$ receptors in the perception of pain. When administered by itself, E-55888 is anti-hyperalgesic but not analgesic, but when administered alongside morphine, E-55888 was found to significantly increase the analgesic effects.

