Gliquidone
# Gliquidone

Gliquidone (INN, sold under the trade name Glurenorm) is an anti-diabetic medication in the sulfonylurea class. It is classified as a second-generation sulfonylurea. It is used in the treatment of diabetes mellitus type 2. It is marketed by the pharmaceutical company Boehringer Ingelheim (Germany).

## Contraindications

* Allergy to sulfonylureas or sulfonamides
* Diabetes mellitus type 1
* Diabetic ketoacidosis
* Patients that underwent removal of the pancreas
* Acute porphyria
* Severe liver disease accompanying with liver insufficiency
* Several conditions (e.g., infectious diseases or major surgical intervention), when insulin administration is required
* Pregnancy or breastfeeding

## Pharmacokinetics

Gliquidone is fully metabolized by the liver. Its metabolites are excreted virtually completely with bile (even with long-term administration), thus allowing the use of medication in diabetic patients with kidney disease and diabetic nephropathy.

