2-Aminopyridine
# 2-Aminopyridine

2-Aminopyridine is an organic compound with the formula $H_2NC_5H_4N.$ It is one of three isomeric aminopyridines. It is a colourless solid that is used in the production of the drugs piroxicam, sulfapyridine, tenoxicam, and tripelennamine. It is produced by the reaction of sodium amide with pyridine, the Chichibabin reaction.

## Structure

Although 2-hydroxypyridine converts significantly to the pyridone tautomer, the related imine tautomer $(HNC_5H_4NH)$ is less important for 2-aminopyridine.

## Toxicity

The acute toxicity is indicated by the LD50 = 200 mg/kg (rat, oral).

