2010 Australian Open – Wheelchair women's singles
# 2010 Australian Open – Wheelchair women's singles

Korie Homan defeated Florence Gravellier in the final, 6–2, 6–2 to win the women's singles wheelchair tennis title at the 2010 Australian Open.

Esther Vergeer was the four-time reigning champion, but did not participate this year.

## Seeds

* Korie Homan (champion)
* Florence Gravellier (final)

## Draw

### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| First round | First round | First round | First round | First round | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| 1 | Korie Homan | $6^5$ | 7 | 6 | | | | | | | | | |
| | Daniela Di Toro | 7 | 5 | 2 | | | | | | | | | |
| | Daniela Di Toro | 7 | 5 | 2 | 1 | Korie Homan | 6 | $6^4$ | 6 | | | | |
| | | | | | | Aniek Van Koot | 1 | 7 | 2 | | | | |
| | Katharina Krüger | 0 | 1 | | | Aniek Van Koot | 1 | 7 | 2 | | | | |
| | Aniek Van Koot | 6 | 6 | | | | | | | | | | |
| | Aniek Van Koot | 6 | 6 | | | | | | | 1 | Korie Homan | 6 | 6 |
| | | | | | | | | | | 2 | Florence Gravellier | 2 | 2 |
| | Annick Sevenans | 3 | $6^5$ | | | | | | | | | | | 2 | Florence Gravellier | 2 | 2 |
| | Jiske Griffioen | 6 | 7 | | | | | | | | | | |
| | Jiske Griffioen | 6 | 7 | | | Jiske Griffioen | 2 | 4 | | | | | |
| | | | | | 2 | Florence Gravellier | 6 | 6 | | | | | |
| | Lucy Shuker | 3 | 6 | 4 | 2 | Florence Gravellier | 6 | 6 | | | | | |
| 2 | Florence Gravellier | 6 | 2 | 6 | | | | | | | | | |
