End organ
# End organ

The term end organ or end-organ has two meanings in medicine:

* A small organ at the terminal end of a nerve conduction pathway
   * Bulbous corpuscle (Ruffini corpuscle end-organ)
   * Tactile corpuscle (Meissner corpuscle end-organ)
   * Merkel nerve ending (Merkel corpuscle end-organ)
   * Neuromuscular junction (motor end-organ)
   * Lamellar corpuscle (Pacinian corpuscle end-organ)
* The ultimately affected organ in a chain of events, such as a disease process (pathophysiology) or a drug's mechanism of action (sometimes called a target organ in this sense)
      * End organ damage, disease of such organs
         * Ambulatory blood pressure § Target organ damage
         * Sepsis § End-organ dysfunction
         * HFE hereditary haemochromatosis § End-organ damage
