2021 Knoxville Challenger – Doubles
# 2021 Knoxville Challenger – Doubles

Hans Hach Verdugo and Adrián Menéndez Maceiras were the defending champions but only Hach Verdugo chose to defend his title, partnering Miguel Ángel Reyes-Varela. Hach Verdugo lost in the final to Malek Jaziri and Blaž Rola.

Jaziri and Rola won the title after defeating Hach Verdugo and Reyes-Varela 3–6, 6–3, [10–5] in the final.

## Seeds

* Hans Hach Verdugo / Miguel Ángel Reyes-Varela (final)
* Treat Huey / Frederik Nielsen (first round)
* Evan King / Hunter Reese (semifinals)
* Robert Galloway / Alex Lawson (quarterfinals)

## Draw

### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

| First round | First round | First round | First round | First round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| 1 | H Hach Verdugo MÁ Reyes-Varela | $6^3$ | $7^7$ | [10] | | | | | | | | | | | | | | | |
| WC | Emile Hudd Shunsuke Mitsui | $7^7$ | $6^4$ | [6] | 1 | H Hach Verdugo MÁ Reyes-Varela | 6 | 2 | [12] | | | | | | | | | | |
| WC | M Damm G Nanda | 4 | 4 | | | J Jung M Krueger | 3 | 6 | [10] | | | | | | | | | | |
| | J Jung M Krueger | 6 | 6 | | | | | | | 1 | H Hach Verdugo MÁ Reyes-Varela | 6 | 5 | [10] | | | | | |
| 3 | E King H Reese | $7^7$ | 6 | | | | | | | 3 | E King H Reese | 3 | 7 | [2] | | | | | |
| Alt | D Marrero Y Uchiyama | $6^3$ | 4 | | 3 | E King H Reese | $7^9$ | 4 | [14] | | | | | | | | | | |
| | C Harrison N Lammons | $6^7$ | 4 | | | T Sandgren M Torpegaard | $6^7$ | 6 | [12] | | | | | | | | | | |
| | T Sandgren M Torpegaard | $7^9$ | 6 | | | | | | | | | | | | 1 | H Hach Verdugo MÁ Reyes-Varela | 6 | 3 | [5] |
| | A Kadhe R Roelofse | 3 | 6 | [6] | | | | | | | | | | | | M Jaziri B Rola | 3 | 6 | [10] |
| | M Jaziri B Rola | 6 | 4 | [10] | | M Jaziri B Rola | 6 | 6 | | | | | | | | | | | |
| WC | Martim Leote Prata J Monday | 3 | 4 | | 4 | R Galloway A Lawson | 2 | 2 | | | | | | | | | | | |
| 4 | R Galloway A Lawson | 6 | 6 | | | | | | | | M Jaziri B Rola | 6 | $6^6$ | [11] | | | | | |
| | JC Aragone D Novikov | 1 | 3 | | | | | | | | R Gonzales C Rungkat | 3 | $7^8$ | [9] | | | | | |
| | R Gonzales C Rungkat | 6 | 6 | | | R Gonzales C Rungkat | 6 | $7^8$ | | | | | | | | | | | |
| | W Blumberg M Schnur | $7^7$ | 6 | | | W Blumberg M Schnur | 4 | $6^6$ | | | | | | | | | | | |
| 2 | T Huey F Nielsen | $6^3$ | 2 | | | | | | | | | | | | | | | | |
