Ethyl bromodifluoroacetate
# Ethyl bromodifluoroacetate

Ethyl bromodifluoroacetate is an ester that can be used to introduce the $CF_2$ group when synthesising chemical compounds. It is a clear to yellow liquid. It is an ester of bromodifluoroacetic acid and ethyl alcohol.

## Formation

Ethyl fluorosulfonoxydifluoroacetate can react with sodium bromide (NaBr) to produce ethyl bromodifluoroacetate. And this reaction could happen in the solvent sulfolane. The reactions takes 12 hours at 100 °C with a yield of 31%.

## Reactions

Ethyl bromodifluoroacetate, and other similar compounds containing a $CF_2$ units can be generated using the Reformatsky reagent with aldehydes and ketones. This yields 2,2-difluoro-3-hydroxy esters. Also ethyl bromdifluoroacetate is considered to be a good compound in generation of compounds and for testing with other organic compounds like lactones, imines and other amino acids.

