2021 FINA World Swimming Championships (25 m) – Women's 4 × 100 metre freestyle relay
# 2021 FINA World Swimming Championships (25 m) – Women's 4 × 100 metre freestyle relay

The Women's 4 × 100 metre freestyle relay competition of the 2021 FINA World Swimming Championships (25 m) was held on 16 December 2021.

## Records

Prior to the competition, the existing world and championship records were as follows.

| World record | Netherlands (NED) | 3:26.53 | Doha, Qatar | 5 December 2014 |
| - | - | - | - | - |
| Competition record | Netherlands (NED) | 3:26.53 | Doha, Qatar | 5 December 2014 |

## Results

### Heats

The heats were started at 12:18.

| Rank | Heat | Lane | Nation | Swimmers | Time | Notes |
| - | - | - | - | - | - | - |
| 1 | 2 | 5 | Netherlands | Kim Busch (53.44) Marrit Steenbergen (52.13) Tessa Giele (53.26) Ranomi Kromowidjojo (52.56) | 3:31.39 | Q |
| 2 | 2 | 4 | United States | Kate Douglass (52.98) Claire Curzan (52.97) Katharine Berkoff (52.95) Torri Huske (53.01) | 3:31.91 | Q |
| 3 | 2 | 3 | China | Zhang Yufei (53.24) Cheng Yujie (52.80) Zhu Menghui (53.22) Wu Qingfeng (52.69) | 3:31.95 | Q |
| 4 | 1 | 5 | Sweden | Michelle Coleman (52.81) Sarah Sjöström (51.45) Sara Junevik (54.01) Louise Hansson (53.79) | 3:32.06 | Q |
| 5 | 2 | 6 | Russian Swimming Federation | Maria Kameneva (52.61) Ekaterina Nikonova (53.15) Arina Surkova (53.26) Daria Klepikova (53.81) | 3:32.83 | Q |
| 6 | 1 | 4 | Canada | Katerine Savard (53.16) Kayla Sanchez (51.76) Rebecca Smith (53.08) Bailey Andison (55.11) | 3:33.11 | Q |
| 7 | 2 | 2 | Hungary | Fanni Gyurinovics (53.33) Zsuzsanna Jakabos (53.56) Nikolett Pádár (54.43) Ajna Késely (54.88) | 3:36.20 | Q, NR |
| 8 | 2 | 8 | Austria | Lena Kreundl (53.95) Cornelia Pammer (54.77) Nina Gangl (55.11) Lena Opatril (54.94) | 3:38.77 | Q |
| 9 | 1 | 3 | Germany | Annika Bruhn (54.75) Marie Pietruschka (54.62) Isabel Marie Gose (55.15) Marlen Kullmann (54.70) | 3:39.22 | |
| 10 | 2 | 7 | South Korea | Jeong So-eun (54.19) Ryu Ji-won (55.67) Han Da-kyung (56.78) Kim Seo-yeong (53.76) | 3:40.40 | NR |
| 11 | 2 | 1 | Slovakia | Lillian Slušná (55.77) Zora Ripková (54.70) Sabína Kupčová (55.57) Tamara Potocká (55.82) | 3:41.86 | NR |
| 12 | 1 | 1 | Thailand | Jenjira Srisaard (55.53) Kornkarnjana Sapianchai (56.28) Kamonchanok Kwanmuang (56.45) Jinjutha Pholjamjumrus (57.63) | 3:45.89 | |
| 13 | 1 | 7 | Turkey | Selen Özbilen (56.33) Nida Eliz Üstündağ (56.87) Merve Tuncel (58.28) Deniz Ertan (57.83) | 3:49.31 | |
| | 1 | 6 | Hong Kong | Katii Tang (55.46) Tam Hoi Lam Natalie Kan Sze Hang Yu | DSQ | |
| | 1 | 2 | Singapore | | DNS | |

### Final

The final will be held at 19:47.

| Rank | Lane | Nation | Swimmers | Time | Notes |
| - | - | - | - | - | - |
| | 7 | Canada | Kayla Sanchez (51.73) Maggie Mac Neil (52.07) Rebecca Smith (52.11) Katerine Savard (52.61) | 3:28.52 | NR |
| | 5 | United States | Kate Douglass (52.39) Claire Curzan (52.25) Katharine Berkoff (52.38) Abbey Weitzeil (51.50) | 3:28.52 | |
| | 6 | Sweden | Sarah Sjöström (51.45) Michelle Coleman (52.06) Sophie Hansson (53.41) Louise Hansson (51.88) | 3:28.80 | NR |
| 4 | 4 | Netherlands | Ranomi Kromowidjojo (52.22) Marrit Steenbergen (51.76) Kim Busch (53.06) Kira Toussaint (51.82) | 3:28.86 | |
| 5 | 3 | China | Cheng Yujie (53.14) Zhang Yufei (52.32) Zhu Menghui (53.05) Wu Qingfeng (52.66) | 3:31.17 | |
| 6 | 2 | Russian Swimming Federation | Maria Kameneva (52.60) Ekaterina Nikonova (52.97) Arina Surkova (53.32) Daria S. Ustinova (52.66) | 3:31.55 | NR |
| 7 | 1 | Hungary | Fanni Gyurinovics (53.78) Zsuzsanna Jakabos (53.40) Nikolett Pádár (54.73) Ajna Késely (55.03) | 3:36.94 | |
| 8 | 8 | Austria | Lena Kreundl (53.39) Cornelia Pammer (55.45) Nina Gangl (55.33) Lena Opatril (55.01) | 3:39.18 | |
