2021 FINA World Swimming Championships (25 m) – Women's 4 × 50 metre freestyle relay
# 2021 FINA World Swimming Championships (25 m) – Women's 4 × 50 metre freestyle relay

The Women's 4 × 50 metre freestyle relay competition of the 2021 FINA World Swimming Championships (25 m) was held on 21 December 2021.

## Records

Prior to the competition, the existing world and championship records were as follows.

| World record | Netherlands (NED) | 1:32.50 | Eindhoven, Netherlands | 12 December 2020 |
| - | - | - | - | - |
| Competition record | United States (USA) | 1:34.03 | Hangzhou, China | 16 December 2018 |

## Results

### Heats

The heats were started at 09:30.

| Rank | Heat | Lane | Nation | Swimmers | Time | Notes |
| - | - | - | - | - | - | - |
| 1 | 1 | 6 | United States | Katharine Berkoff (24.43) Torri Huske (24.44) Kate Douglass (23.39) Abbey Weitzeil (23.62) | 1:35.88 | Q |
| 2 | 1 | 4 | Netherlands | Kim Busch (24.30) Marrit Steenbergen (24.16) Tessa Giele (23.95) Maaike de Waard (23.86) | 1:36.27 | Q |
| 3 | 2 | 3 | Sweden | Sarah Sjöström (23.50) Michelle Coleman (23.98) Sara Junevik (24.31) Hanna Rosvall (24.76) | 1:36.55 | Q |
| 4 | 2 | 4 | Russian Swimming Federation | Rozaliya Nasretdinova (24.42) Daria Klepikova (24.53) Ekaterina Nikonova (24.35) Daria S. Ustinova (23.84) | 1:37.14 | Q |
| 5 | 1 | 2 | China | Cheng Yujie (24.59) Zhang Yufei (23.95) Zhu Menghui (24.19) Wu Qingfeng (24.76) | 1:37.49 | Q |
| 6 | 2 | 5 | France | Marie Wattel (24.49) Charlotte Bonnet (24.14) Analia Pigrée (24.74) Béryl Gastaldello (24.21) | 1:37.58 | Q |
| 7 | 2 | 7 | Canada | Kayla Sanchez (24.45) Maggie Mac Neil (24.58) Katerine Savard (25.81) Rebecca Smith (25.61) | 1:40.45 | Q |
| 8 | 1 | 1 | Hong Kong | Tam Hoi Lam (25.21) Stephanie Au (25.17) Chan Kin Lok (25.22) Sze Hang Yu (25.04) | 1:40.64 | Q |
| 9 | 2 | 6 | Turkey | Ekaterina Avramova (25.07) Selen Özbilen (25.66) Viktoriya Zeynep Güneş (24.97) Nida Eliz Üstündağ (25.93) | 1:41.63 | |
| 10 | 1 | 7 | Thailand | Jenjira Srisaard (24.80) Kornkarnjana Sapianchai (25.47) Kamonchanok Kwanmuang (26.27) Jinjutha Pholjamjumrus (26.35) | 1:42.89 | |
| 11 | 2 | 1 | South Korea | Jeong So-eun (25.37) Kim Seo-yeong (25.39) Han Da-kyung (26.88) Ryu Ji-won (26.17) | 1:43.81 | |
| | 1 | 3 | Slovakia | | DNS | |
| | 1 | 5 | Italy | | DNS | |
| | 2 | 2 | Singapore | | DNS | |

### Final

The final was held at 18:00.

| Rank | Lane | Nation | Swimmers | Time | Notes |
| - | - | - | - | - | - |
| | 4 | United States | Abbey Weitzeil (23.59) Claire Curzan (23.40) Katharine Berkoff (23.81) Kate Douglass (23.42) | 1:34.22 | |
| | 3 | Sweden | Sarah Sjöström (23.33) Michelle Coleman (23.38) Sara Junevik (24.02) Louise Hansson (23.81) | 1:34.54 | NR |
| | 5 | Netherlands | Kim Busch (24.29) Maaike de Waard (23.71) Kira Toussaint (24.01) Ranomi Kromowidjojo (22.88) | 1:34.89 | |
| 4 | 2 | China | Cheng Yujie (24.27) Zhang Yufei (23.12) Zhu Menghui (23.90) Wu Qingfeng (23.71) | 1:35.00 | AS |
| 5 | 6 | Russian Swimming Federation | Maria Kameneva (23.59) Arina Surkova (23.99) Daria S. Ustinova (23.92) Rozaliya Nasretdinova (23.90) | 1:35.40 | |
| 6 | 1 | Canada | Kayla Sanchez (23.87) Maggie Mac Neil (23.50) Katerine Savard (24.46) Rebecca Smith (24.04) | 1:35.87 | |
| 7 | 7 | France | Marie Wattel (24.42) Béryl Gastaldello (23.61) Charlotte Bonnet (23.90) Analia Pigrée (24.43) | 1:36.36 | |
| 8 | 8 | Hong Kong | Tam Hoi Lam (24.70) Stephanie Au (24.68) Chan Kin Lok (25.21) Sze Hang Yu (24.76) | 1:39.35 | NR |
