1-(2-Diphenyl)piperazine
# 1-(2-Diphenyl)piperazine

1-(2-Diphenyl)piperazine, also known as RA-7, is a drug which acts as a potent and selective antagonist at the $5HT_7$ serotonin receptor. It was discovered as an active metabolite of the synthetic $5-HT_7$ agonists LP-12 and LP-211, and unexpectedly turned out to be a potent antagonist with selectivity approaching that of the parent molecules, despite its much simpler structure.

