TTC37
# TTC37

TTC37 (Tetratricopeptide repeat domain 37) is a protein which in humans is encoded by gene TTC37, located on chromosome 5.

## Structure

The length of the polypeptide chain is 1,564 amino acids, and the molecular weight is 175,486 Da. TTC37 contains six tetratricopeptide repeat domains.

## Function

TTC37 is a component of the Ski complex which is involved in exosome mediated RNA decay.

## Subcellular distribution

It is localized in the cytoplasmatic space and the cell nucleus.

## Clinical significance

Mutation in the TTC37 gene are associated with tricho-hepato-enteric syndrome.

