Placental site nodule
# Placental site nodule

A placental site nodule (PSN) is benign remnant from a previous pregnancy.

## Presentation

They are typically asymptomatic and found incidentally.

## Pathology

PSNs are intermediate trophoblastic remnants.

## Diagnosis

PSNs are diagnosed by examining the tissue under a microscope, usually obtained with a dilation and curettage.

Typically, they consist of pink (hyaline) material using the standard stain and contain few cells. Bizarre multinucleated cells may be present; however, there is no mitotic activity. The differential diagnosis includes (cervical) squamous cell carcinoma, gestational trophoblastic disease, and exaggerated placental site.

## Prognosis

PSN are benign. Once removed, they do not require any treatment and do not recur.

