Commission Regulation (EC) No 508/1999 of 4 March 1999 amending Annexes I to IV to Council Regulation (EEC) No 2377/90 laying down a Community procedure for the establishment of maximum residue limits of veterinary medicinal products in foodstuffs of animal origin
L 60/16 EN Official Journal of the European Communities 9. 3. 1999 COMMISSION REGULATION (EC) No 508/1999 of 4 March 1999 amending Annexes I to IV to Council Regulation (EEC) No 2377/90 laying down a Community procedure for the establishment of maximum residue limits of veterinary medicinal products in foodstuffs of animal origin THE COMMISSION OF THE EUROPEAN COMMUNITIES, Having regard to the Treaty establishing the European Community, Having regard to Council Regulation (EEC) No 2377/90 of 26 June 1990 laying down a Community procedure for the establishment of maximum residue limits of veter- inary medicinal products in foodstuffs of animal origin (1), as last amended by Commission Regulation (EC) No 2728/98 (2), and in particular Articles 6, 7 and 8 thereof, Whereas, since the adoption of Regulation (EEC) No 2377/90, the Annexes have been amended a number of times; whereas, since the texts are numerous, complex and dispersed among various Official Journals, they are difficult to use and thus lack the clarity which should be an essential feature of all legislation; whereas, certain of those Annexes should therefore be consolidated; whereas on the same occasion the name or chemical description of some compounds should be rectified or made more precise and certain material errors should be corrected; Whereas the measures provided for in this Regulation are in accordance with the opinion of the Standing Committee on Veterinary Medicinal Products, HAS ADOPTED THIS REGULATION: Article 1 Annexes I to IV to Regulation (EEC) No 2377/90 are hereby replaced by the texts set out in the Annex to this Regulation. Article 2 This Regulation shall enter into force on the 60th day following that of its publication in the Official Journal of the European Communities. This Regulation shall be binding in its entirety and directly applicable in all Member States. Done at Brussels, 4 March 1999. For the Commission Martin BANGEMANN Member of the Commission (1) OJ L 224, 18. 8. 1990, p. 1. (2) OJ L 343, 18. 12. 1998, p. 8. LIST OF PHARMACOLOGICALLY ACTIVE SUBSTANCES FOR WHICH MAXIMUM RESIDUE LIMITS HAVE BEEN FIXED ANNEX I Anti-infectious agents Chemotheurapeutics 1. 1. 1. 1. 1. 1. Sulfonamides Pharmacologically active substance(s) All substances belonging to the sulfonamide group Marker residue Animal species MRLs Target tissues Other provisions Parent drug All food-producing species Bovine, ovine, caprine 100 lg/kg Muscle 100 lg/kg 100 lg/kg 100 lg/kg Kidney 100 lg/kg Milk Fat Liver The combined total residues of all substances within the sulfonamide group should not exceed 100 lg/kg 1. 1. 2. Diamino pyrimidine derivatives Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Baquiloprim Baquiloprim Bovine Porcine Trimethoprim Trimethoprim Bovine Porcine Equidae Fat Liver 10 lg/kg 300 lg/kg 150 lg/kg Kidney 30 lg/kg Milk 40 lg/kg 50 lg/kg 50 lg/kg Kidney Skin and fat Liver Fat Liver 50 lg/kg Muscle 50 lg/kg 50 lg/kg 50 lg/kg Kidney 50 lg/kg Milk 50 lg/kg Muscle 50 lg/kg 50 lg/kg 50 lg/kg Kidney 100 lg/kg Muscle 100 lg/kg 100 lg/kg 100 lg/kg Kidney Fat Liver Skin and fat Liver 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 1 7 Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Poultry Not for use in animals from which eggs are produced for human consumption Fin fish 50 lg/kg Muscle 50 lg/kg 50 lg/kg 50 lg/kg Kidney 50 lg/kg Muscle and Skin and fat Liver skin in natural proportions 1. 2. Antibiotics 1. 2. 1. Penicillins Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Amoxicyllin Amoxicyllin All food-producing species Ampicillin Ampicillin All food-producing species Benzylpenicillin Benzylpenicillin All food-producing species Cloxacillin Cloxacillin All food-producing species 50 lg/kg Muscle 50 lg/kg 50 lg/kg 50 lg/kg Kidney 4 lg/kg Milk Fat Liver 50 lg/kg Muscle 50 lg/kg 50 lg/kg 50 lg/kg Kidney 4 lg/kg Milk Fat Liver 50 lg/kg Muscle 50 lg/kg 50 lg/kg 50 lg/kg Kidney 4 lg/kg Milk Fat Liver 300 lg/kg Muscle 300 lg/kg 300 lg/kg 300 lg/kg Kidney 30 lg/kg Milk Fat Liver L 6 0 / 1 8 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Dicloxacillin Dicloxacillin All food-producing species Oxacillin Oxacillin All food-producing species Penethamate Benzylpenicillin Bovine 300 lg/kg Muscle 300 lg/kg 300 lg/kg 300 lg/kg Kidney 30 lg/kg Milk Fat Liver 300 lg/kg Muscle 300 lg/kg 300 lg/kg 300 lg/kg Kidney 30 lg/kg Milk Fat Liver 50 lg/kg Muscle 50 lg/kg 50 lg/kg 50 lg/kg Kidney 4 lg/kg Milk Fat Liver 1. 2. 2. Cephalosporins Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Cefazolin Cefazolin Bovine, ovine, caprine 50 lg/kg Milk Cefquinome Cefquinome Bovine 50 lg/kg Muscle 50 lg/kg 100 lg/kg 200 lg/kg Kidney 20 lg/kg Milk Fat Liver 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 1 9 1. 2. 3. Quinolones Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Danofloxacin Danofloxacin Bovine Not for use in animals from which milk is produced for human consumption Chicken Not for use in animals from which eggs are produced for human consumption Fat Liver 200 lg/kg Muscle 100 lg/kg 400 lg/kg 400 lg/kg Kidney 200 lg/kg Muscle 100 lg/kg 400 lg/kg 400 lg/kg Kidney Skin and fat Liver Difloxacin Difloxacin Chicken, turkey 300 lg/kg Muscle 400 lg/kg 1 900 lg/kg Skin and fat Liver 600 lg/kg Kidney Enrofloxacin Sum of enrofloxacin and ciprofloxacin Bovine Rabbits Porcine Poultry Not for use in animals from which eggs are produced for human consumption Fat Liver Fat Liver 100 lg/kg Muscle 100 lg/kg 300 lg/kg 200 lg/kg Kidney 100 lg/kg Milk 100 lg/kg Muscle 100 lg/kg 200 lg/kg 300 lg/kg Kidney 100 lg/kg Muscle 100 lg/kg 200 lg/kg 300 lg/kg Kidney 100 lg/kg Muscle 100 lg/kg 200 lg/kg 300 lg/kg Kidney Skin and fat Liver Skin and fat Liver L 6 0 / 2 0 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Sarafloxacin Sarafloxacin Chicken Salmonidae 10 lg/kg 100 lg/kg 30 lg/kg Muscle and Skin and fat Liver skin in natural proportions 1. 2. 4. Macrolides Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Spiramycin Sum of spiramycin and neospiramycin Bovine Chicken Tilmicosin Tilmicosin Bovine, ovine, porcine Ovine Chicken Tylosin Tylosin A Bovine Fat Liver 200 lg/kg Muscle 300 lg/kg 300 lg/kg 300 lg/kg Kidney 200 lg/kg Milk 200 lg/kg Muscle 300 lg/kg 400 lg/kg Skin and fat Liver Fat Liver 50 lg/kg Muscle 50 lg/kg 1 000 lg/kg 1 000 lg/kg Kidney 50 lg/kg Milk 75 lg/kg Muscle 75 lg/kg 1 000 lg/kg Skin and fat Liver 250 lg/kg Kidney 100 lg/kg Muscle 100 lg/kg 100 lg/kg 100 lg/kg Kidney 50 lg/kg Milk Fat Liver Not for use in animals from which eggs are produced for human consumption 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 2 1 Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Porcine Poultry Not for use in hens producing eggs for human consumption Skin and fat Liver 100 lg/kg Muscle 100 lg/kg 100 lg/kg 100 lg/kg Kidney 100 lg/kg Muscle 100 lg/kg 100 lg/kg 100 lg/kg Kidney Skin and fat Liver 1. 2. 5. Florfenicol and related compounds Pharmacologically active substance(s) Florfenicol Marker residue Animal species MRLs Target tissues Other provisions Sum of florfenicol and its metabolites measured as florfenicol-amine Bovine 200 lg/kg Muscle 3 000 lg/kg Liver 300 lg/kg Kidney Thiamphenicol Thiamphenicol Bovine Chicken Not for use in animals from which eggs are produced for human consumption Fat Liver 50 lg/kg Muscle 50 lg/kg 50 lg/kg 50 lg/kg Kidney 50 lg/kg Milk 50 lg/kg Muscle 50 lg/kg 50 lg/kg 50 lg/kg Kidney Skin and fat Liver 1. 2. 6. Tetracyclines Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Chlortetracycline Sum of parent drug and All food-producing species its 4- epimer Liver 100 lg/kg Muscle 300 lg/kg 600 lg/kg Kidney 100 lg/kg Milk Eggs 200 lg/kg L 6 0 / 2 2 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Doxycycline Doxycycline Bovine Not for use in animals from which milk is produced for human consumption Porcine Poultry Not for use in animals from which eggs are produced for human consumption Oxytetracycline Sum of parent drug and All food-producing species its 4-epimer Tetracycline Sum of parent drug and All food-producing species its 4-epimer Skin and fat Liver Skin and fat Liver Liver 100 lg/kg Muscle 300 lg/kg 600 lg/kg Kidney 100 lg/kg Muscle 300 lg/kg 300 lg/kg 600 lg/kg Kidney 100 lg/kg Muscle 300 lg/kg 300 lg/kg 600 lg/kg Kidney Liver 100 lg/kg Muscle 300 lg/kg 600 lg/kg Kidney 100 lg/kg Milk Eggs 200 lg/kg Liver 100 lg/kg Muscle 300 lg/kg 600 lg/kg Kidney 100 lg/kg Milk Eggs 200 lg/kg 1. 2. 7. Naphtalene-ringed ansamycin Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Rifaximin Rifaximin Bovine 60 lg/kg Milk 1. 2. 8. Pleuromutilines Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Valnemulin Valnemulin Porcine 50 lg/kg Muscle 500 lg/kg 100 lg/kg Kidney Liver 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 2 3 Antiparasitic agents Agents acting against endoparasites 2. 2. 1. 2. 1. 1. Salicylanilides Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Closantel Closantel Bovine Ovine Fat Liver 1 000 lg/kg Muscle 3 000 lg/kg 1 000 lg/kg 3 000 lg/kg Kidney 1 500 lg/kg Muscle 2 000 lg/kg 1 500 lg/kg 5 000 lg/kg Kidney Fat Liver 2. 1. 2. Tatra-hydro-imidazoles (imidazolthiazoles) Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Levamisole Levamisole Bovine, ovine, porcine, poultry 10 lg/kg Muscle 10 lg/kg 100 lg/kg 10 lg/kg Kidney Fat Liver 2. 1. 3. Benzimidazoles and pro-benzimidazoles Marker residue Animal species MRLs Target tissues Other provisions Pharmacologically active substance(s) Albendazole Bovine, ovine albendazole Sum of sulphoxide, albendazole sulphone, and albenda- zole 2-amino sulphone, expressed as albendazole Febantel Sum of extractable resi- be dues which may oxidised to oxfendazole Bovine, ovine Bovine, ovine, porcine, equidae 100 lg/kg Muscle 100 lg/kg 1 000 lg/kg Fat Liver 500 lg/kg Kidney 100 lg/kg Milk 10 lg/kg Milk 50 lg/kg Muscle 50 lg/kg 500 lg/kg 50 lg/kg Kidney Fat Liver L 6 0 / 2 4 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 Pharmacologically active substance(s) Fenbendazole Marker residue Animal species MRLs Target tissues Other provisions Sum of extractable resi- dues which may be oxidised to oxfendazole sulphone Bovine, ovine Bovine, ovine, porcine, equide 10 lg/kg Milk 50 lg/kg Muscle 50 lg/kg 500 lg/kg 50 lg/kg Kidney Fat Liver Flubendazole Oxfendazole Sum of flubendazole and (2-amino 1H-benzimida- zol-5-yl) (4fluorophenyl) methanone Porcine, chicken, game birds Flubendazole Chicken Sum of extractable resi- dues which may be oxidised to oxfendazole sulphone Bovine, ovine Bovine, ovine, porcine, equidae Oxibendazole Oxibendazole Porcine Thiabendazole Sum of thiabendazole and 5-hydroxythiabenda- zole Bovine Triclabendazole Sum of extractable resi- dues be that may oxidised to ketotricla- bendazole Bovine, ovine 50 lg/kg Muscle 50 lg/kg 400 lg/kg 300 lg/kg Kidney 400 lg/kg Eggs Skin and fat Liver 10 lg/kg Milk 50 lg/kg Muscle 50 lg/kg 500 lg/kg 50 lg/kg Kidney Fat Liver 100 lg/kg Muscle 500 lg/kg 200 lg/kg 100 lg/kg Kidney Skin and fat Liver 100 lg/kg Muscle 100 lg/kg 100 lg/kg 100 lg/kg Kidney 100 lg/kg Milk Fat Liver 100 lg/kg Muscle 100 lg/kg 100 lg/kg Kidney Liver Not for use in animals from which milk is produced for human consumption 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 2 5 2. 2. Agents acting against ectoparasites 2. 2. 1. Organophosphates Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Diazinon Diazinon Bovine, ovine, caprine Bovine, porcine, ovine, caprine 20 lg/kg Milk 20 lg/kg Muscle 700 lg/kg 20 lg/kg 20 lg/kg Kidney Fat Liver 2. 2. 2. Formamidines Pharmacologically active substance(s) Amitraz 2. 2. 3. Pyrethroids Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Sum of amitraz and all metabolites containing the 2,4-DMA moiety, expressed as amitraz Bovine Ovine Porcine Fat Liver 200 lg/kg 200 lg/kg 200 lg/kg Kidney 10 lg/kg Milk 400 lg/kg 100 lg/kg 200 lg/kg Kidney 10 lg/kg Milk 400 lg/kg 200 lg/kg 200 lg/kg Kidney Fat Liver Skin and fat Liver Marker residue Animal species MRLs Target tissues Other provisions Flumethrin Flumethrin trans-Z isomers) (sum of Bovine 10 lg/kg Muscle 150 lg/kg 20 lg/kg 10 lg/kg Kidney 30 lg/kg Milk Fat Liver L 6 0 / 2 6 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 2. 3. Agents acting against endo- and ectoparasites 2. 3. 1. Avermectins Phramacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Abamectin Avermectin B1a Bovine 10 lg/kg 20 lg/kg Fat Liver Not for use in bovine from which milk is produced for human consumption for use in ovine from which milk is Not produced for human consumption Doramectin Doramectin Bovine Porcine, ovine Eprinomectin Eprinomectin B1a Bovine Ivermectin 23-Dihydro-aver- 22, mectin B1a Bovine Porcine, ovine, equidae Deer, including reindeer Fat Liver 10 lg/kg Muscle 150 lg/kg 100 lg/kg 30 lg/kg Kidney 20 lg/kg Muscle 100 lg/kg 50 lg/kg 30 lg/kg Kidney Fat Liver 30 lg/kg Muscle 30 lg/kg 600 lg/kg 100 lg/kg Kidney 30 lg/kg Milk Fat Liver Fat Liver Fat Liver 40 lg/kg 100 lg/kg 20 lg/kg 15 lg/kg 20 lg/kg Muscle 100 lg/kg 50 lg/kg 20 lg/kg Kidney Fat Liver Moxidectin Moxidectin Bovine, ovine 50 lg/kg Muscle 500 lg/kg 100 lg/kg 50 lg/kg Kidney Fat Liver 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 2 7 2. 4. Agents acting against protozoa 2. 4. 1. Triazinetrione derivative Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Toltrazuril Toltrazuril sulfone Chicken Turkey 3. Agents acting on the nervous system 3. 1. Agents acting on the central nervous system 3. 1. 1. Butyrophenone tranquillisers Not for use in animals from which eggs are produced for human consumption Skin and fat Liver 100 lg/kg Muscle 200 lg/kg 600 lg/kg 400 lg/kg Kidney 100 lg/kg Muscle 200 lg/kg 600 lg/kg 400 lg/kg Kidney Skin and fat Liver Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Azaperone Sum of azaperone and azaperol Porcine 100 lg/kg Muscle 100 lg/kg 100 lg/kg 100 lg/kg Kidney Skin and fat Liver 3. 2. Agents acting on the autonomic nervous system 3. 2. 1. Anti-adrenergics Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Carazolol Carazolol Porcine 5 lg/kg Muscle 5 lg/kg 25 lg/kg 25 lg/kg Kidney Skin and fat Liver L 6 0 / 2 8 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 Anti-inflammatory agents 4. 4. 1. Nonsteroidal anti-inflammatory agents 4. 1. 1. Arylpropionic acid derivative Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Vedaprofen Vedaprofen Equidae 50 lg/kg Muscle 20 lg/kg 100 lg/kg Fat Liver 1 000 lg/kg Kidney 4. 1. 2. Fenamate group derivatives Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Tolfenamic acid Tolfenamic acid Bovine Porcine Liver 50 lg/kg Muscle 400 lg/kg 100 lg/kg Kidney 50 lg/kg Milk 50 lg/kg Muscle 400 lg/kg 100 lg/kg Kidney Liver 5. 5. 1. Corticoides Glucocorticoides Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Dexamethasone Dexamethasone Bovine Bovine, porcine, equidae 0,3 lg/kg Milk 0,75 lg/kg Muscle 2 lg/kg Liver 0,75 lg/kg Kidney 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 2 9 LIST OF SUBSTANCES NOT SUBJECT TO MAXIMUM RESIDUE LIMITS ANNEX II 1. Inorganic chemicals Pharmacologically active substance(s) Animal species Other provisions Aluminium distearate All food-producing species Aluminium hydroxide acetate All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species For oral use only All food-producing species For oral use only All food-producing species For oral use only All food-producing species For oral use only All food-producing species All mammalian food-producing species For topical use only All food-producing species Aluminium phosphate Aluminium tristearate Ammonium chloride Bismuth subcarbonate Bismuth subgallate Bismuth subnitrate Bismuth subsalicylate Boric acid and borates Bromide, sodium salt Calcium acetate Calcium benzoate Calcium carbonate Calcium chloride Calcium gluconate Calcium hydroxide Calcium hypophosphite Calcium malate Calcium oxide Calcium phosphate Calcium polyphosphates Calcium propionate Calcium silicate Calcium stearate Calcium sulphate L 6 0 / 3 0 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 Pharmacologically active substance(s) Animal species Other provisions Calcium glucoheptonate Calcium glucono glucoheptonate Calcium gluconolactate Calcium glutamate Cobalt carbonate Cobalt dichloride Cobalt gluconate Cobalt oxide Cobalt sulphate Cobalt trioxide Copper chloride Copper gluconate Copper heptanoate Copper methionate Copper oxide Copper sulphate Dicopper oxide Hydrochloric acid Hydrogen peroxide Iodine and iodine inorganic compounds including: — Sodium and potassium-iodide — Sodium and potassium-iodate — Iodophors including polyvinylpyrrolidone-iodine Iron dichloride Iron sulphate All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species For use as excipient All food-producing species All food-producing species All food-producing species All food-producing species 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 3 1 Pharmacologically active substance(s) Animal species Other provisions Magnesium Magnesium sulphate Magnesium hydroxide Magnesium stearate Magnesium glutamate Magnesium orotate Magnesium aluminium silicate Magnesium oxide Magnesium carbonate Magnesium phosphate Magnesium glycerophosphate Magnesium aspartate Magnesium citrate Magnesium acetate Magnesium trisilicate Nickel gluconate Nickel sulphate Potassium DL-aspartate Potassium glucuronate Potassium glycerophosphate Potassium nitrate Potassium selenate Sodium chlorite Sodium dichloroisocyanurate Sodium hypophosphite Sodium selenate Sodium selenite Sulphur Zinc acetate Zinc chloride Zinc gluconate Zinc oleate Zinc stearate All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species Bovine Bovine, ovine, caprine All food-producing species All food-producing species All food-producing species Bovine, porcine, ovine, caprine, equidae All food-producing species For topical use only For topical use only L 6 0 / 3 2 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 2. Organic compounds Pharmacologically active substance(s) Animal species Other provisions 17b-Oestradiol 2-Aminoethanol All mammalian food-producing species For therapeutic and zootechnical uses only All food-producing species 2-Aminoethyl dihydrogenphosphate All food-producing species 2-Pyrrolidone 8-Hydroxyquinoline Acetyl cysteine Alfacalcidol Alfaprostol Bacitracin All food-producing species At parenteral doses up to 40 mg/kg bw All mammalian food-producing species For topical use in newborn animals only All food-producing species Bovine For parturient cows only Rabbits Bovine, porcine, equidae Bovine For intramammary use in lactating cows only and for all tissues except milk Benzalkonium chloride All food-producing species For use as an excipient at concentrations up to 0,05 % only Benzocaine Benzylalcohol Betaine Bronopol Brotizolam Buserelin All food-producing species For use as local anaesthetic only All food-producing species For use as excipient All food-producing species Salmonidae Bovine All food-producing species For use only on farmed fertilised eggs For therapeutic uses only Butorphanol tartrate Equidae For intravenous administration only Butyl 4-hydroxybenzoate All food-producing species 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 3 3 Pharmacologically active substance(s) Animal species Other provisions Butylscopolaminium bromide Caffeine Carbetocin Cefazolin Cetostearyl alcohol Cetrimide Chlorhexidine Chlorocresol Clazuril Cloprostenol All food-producing species All food-producing species All mammalian food-producing species Bovine Ovine, caprine All food-producing species All food-producing species For intramammary use, except if the udder may be used as food for human consumption All food-producing species For topical use only All food-producing species Pigeon Bovine, porcine, equidae Coco alkyl dimethyl betaines All food-producing species For use as excipient Corticotropin All food-producing species D-Phe 6 -luteinising-hormone releasing hormone All food-producing species Dembrexine Denaverine hydrochloride Detomidine Diclazuril Diethyl phtalate Equidae Bovine Bovine, equidae Ovine All food-producing species For therapeutic uses only For oral use in lambs only Diethylene glycol monoethyl ether Bovine, porcine Dimanganese trioxide Dimethyl phtalate Dinoprost All food-producing species For oral use only All food-producing species All mammalian food-producing species Dinoprost tromethamine All mammalian food-producing species L 6 0 / 3 4 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 Pharmacologically active substance(s) Animal species Other provisions Diprophylline Etamiphylline camsylate Ethanol Ethyl lactate Etiproston tromethamine Fertirelin acetate Flumethrin Folic acid Glycerol formal All food-producing species All food-producing species All food-producing species For use as excipient All food-producing species Bovine, porcine Bovine Bees (honey) All food-producing species All food-producing species Gonadotrophin releasing hormone All food-producing species Heptaminol Hesperidin Hesperidin methyl chalcone Hexetidine All food-producing species Equidae Equidae Equidae Human chorion gonadotrophin All food-producing species Human menopausal urinary gonadotrophin Bovine For topical use only Hydrocortisone Iodine organic compounds — Iodoform Isobutane Isoflurane Isoxsuprine Ketamine All food-producing species For topical use only All food-producing species All food-producing species Equidae Bovine, equidae All food-producing species For use as anaesthetic only For therapeutic use only in accordance with Council Directive 96/22/EEC (OJ L 125, 23. 5. 1996, p. 3) Ketanserin tartrate Equidae 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 3 5 Pharmacologically active substance(s) Animal species Other provisions Ketoprofen Bovine, porcine, equidae L-tartaric acid and its mono- and di-basic salt of sodium, potassium and calcium All food-producing species For use as excipient Lactic acid Lecirelin Lobeline Luprostiol Malic acid Manganese carbonate Manganese chloride Manganese gluconate Manganese glycerophosphate Manganese oxide Manganese pidolate Manganese ribonucleate Manganese sulphate Mecillinam Medroxyprogesterone acetate Melatonin Menadione Menbutone Menthol All food-producing species Bovine, equidae, rabbits All food-producing species All mammalian species All food-producing species For use as excipient For oral use only For oral use only For oral use only For oral use only For oral use only For oral use only For oral use only For oral use only For intrauterine use only For intravaginal use for zootechnical purposes only All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species Bovine Ovine Ovine, caprine All food-producing species Bovine, ovine, caprine, porcine, equidae All food-producing species Methyl nicotinate Bovine, equidae For topical use only Mineral hydrocarbons, low to high viscosity including microcristal- line waxes, approximately C10-C60; aliphatic, branched aliphatic and alicyclic compounds All food-producing species Excludes aromatic and unsaturated compounds L 6 0 / 3 6 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 Pharmacologically active substance(s) Animal species Other provisions N-butane N-butanol Natamycin Neostigmine Nicoboxil Nonivamide Oleyloleate Oxytocin Pancreatin Papain Papaverine Peracetic acid Phenol Phloroglucinol Phytomenadione Policresulen All food-producing species All food-producing species For use as excipient Bovine, equidae For topical use only All food-producing species Equidae Equidae For topical use only For topical use only All food-producing species For topical use only All mammalian food-producing species All mammalian food-producing species For topical use only All food-producing species Bovine Newborn calves only All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species For topical use only Polyethylene glycol 15 hydroxystearate All food-producing species For use as excipient Polyethylene glycol 7 glyceryl cocoate All food-producing species For topical use only Polyethylene glycol stearates with 8-40 oxyethylene units All food-producing species For use as excipient Polysulphated glycosaminoglycan Equidae 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 3 7 Pharmacologically active substance(s) Animal species Other provisions Praziquantel Ovine Equidae For use in non-lactating sheep only Pregnant mare serum gonadotrophin All food-producing species Prethcamide (crotethamide and cropropamide) All mammalian food-producing species Procaine Propane Propylene glycol Quatresin R-Cloprostenol Rifaximin Romifidine All food-producing species All food-producing species All food-producing species All food-producing species For use as preservative only at concentrations of up to 0,5 % Bovine, porcine, equidae All mammalian food-producing species For topical use only Bovine Equidae For intramammary use, except if the udder may be used as food for human consumption For therapeutic uses only Sodium 2-methyl-2-phenoxy-propanoate Bovine, porcine, caprine, equidae Sodium benzyl 4-hydroxybenzoate All food-producing species Sodium butyl 4-hydroxybenzoate All food-producing species Sodium cetostearyl sulphate All food-producing species For topical use only Somatosalm Tanninum Tau fluvalinate Terpin hydrate Tetracaine Salmon All food-producing species Bovine, porcine, ovine, caprine All food-producing species For use as anaesthetic only L 6 0 / 3 8 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 Pharmacologically active substance(s) Animal species Other provisions Theobromine Theophylline Thiomersal Thymol Timerfonate Trimethylphloroglucinol Vitamin D Wool alcohols All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species For use only as preservatives in multidose vaccines at a concentra- tion not exceeding 0,02 % For use only as preservatives in multidose vaccines at a concentra- tion not exceeding 0,02 % All food-producing species For topical use only 3. Substances generally recognised as safe Pharmacologically active substance(s) Animal species Other provisions Absinthium extract Acetylmethionine Aluminium hydroxide Aluminium monostearate Ammonium sulfate Benzoyl benzoate Benzyl p-hydroxybenzoate Calcium borogluconate Calcium citrate Camphor Cardamon extract Diethyl sebacate Dimethicone All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species External use only All food-producing species All food-producing species All food-producing species 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 3 9 Pharmacologically active substance(s) Animal species Other provisions Dimethyl acetamide Dimethyl sulphoxide Epinephrine Ethyl oleate All food-producing species All food-producing species All food-producing species All food-producing species Ethylenediaminetetraacetic acid and salts All food-producing species Eucalyptol All food-producing species Follicle stimulating hormone (natural FSH from all species and their synthetic analogues) All food-producing species Formaldehyde Formic acid Glutaraldehyde Guaiacol Heparin and its salts All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species Human chorionic gonadotropin (natural HCG and its synthetic analogues) All food-producing species Iron ammonium citrate Iron dextran Iron glucoheptonate Isopropanol Lanolin All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species Luteinising hormone (natural LH from all species and their synthetic analogues) All food-producing species Magnesium chloride Magnesium gluconate All food-producing species All food-producing species L 6 0 / 4 0 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 Pharmacologically active substance(s) Animal species Other provisions (molecular weight ranging from 200 to All food-producing species Magnesium hypophosphite Mannitol Methylbenzoate Monothioglycerol Montanide Myglyol Orgotein Poloxalene Poloxamer Polyethylene glycols 10 000) Polysorbate 80 Serotonin Sodium chloride Sodium cromoglycate Sodium dioctylsulphosuccinate Sodium formaldehydesulphoxylate Sodium lauryl sulphate Sodium pyrosulphite Sodium stearate Sodium thiosulphate Tragacanth Urea Zinc oxide Zinc sulphate All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 4 1 4. Substances used in homeopathic veterinary medicinal products Pharmacologically active substance(s) Animal species Other provisions All substances used in homeopathic veterinary medicinal products provided that their concentration in the product does not exceed one part per ten thousand All food-producing species 5. Substances used as food additives in foodstuffs for human consumption Pharmacologically active substance(s) Animal species Other provisions Substances with an E number All food-producing species Only substances approved as additives in foodstuffs for human consumption, with the exception of preservatives listed in part C of Annex III to European Parliament and Council Directive 95/2/EC (OJ L 61, 18. 3. 1995, p. 1). 6. Substances of vegetable origin Pharmacologically active substance(s) Animal species Other provisions Angelicae radix aetheroleum Anisi aetheroleum Balsamum peruvianum Carvi aetheroleum Caryophylli aetheroleum All food-producing species All food-producing species All food-producing species For topical use only All food-producing species All food-producing species Chrysanthemi cinerariifolii flos All food-producing species For topical use only Cinnamomi cassiae aetheroleum All food-producing species Cinnamomi ceylanici aetheroleum All food-producing species Citri aetheroleum Citronellae aetheroleum Coriandri aetheroleum Echinacea purpurea Eucalypti aetheroleum Foeniculi aetheroleum All food-producing species All food-producing species All food-producing species All food-producing species For topical use only All food-producing species All food-producing species L 6 0 / 4 2 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 Pharmacologically active substance(s) Animal species Other provisions Hamamelis virginiana Hyperici oleum Lespedeza capitata Lini oleum Majoranae herba Matricariae flos For topical use only For topical use only All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species Medicago sativa extractum All food-producing species For topical use only Melissae folium All food-producing species Menthae piperitae aetheroleum All food-producing species Millefolii herba Myristicae aetheroleum All food-producing species All food-producing species For use in newborn animals only Oxidation products of Terebinthinae oleum Bovine, porcine, ovine, caprine Pyrethrum extract Quercus cortex Quillaia saponins Ricini oleum Rosmarini aetheroleum Rosmarini folium Salviae folium Sambuci flos Sinapis nigrae semen All food-producing species For topical use only All food-producing species All food-producing species All food-producing species For use as excipient All food-producing species All food-producing species All food-producing species All food-producing species All food-producing species Terebinthinae aetheroleum rectificatum All food-producing species For topical use only 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 4 3 Pharmacologically active substance(s) Animal species Other provisions Terebinthinae laricina Thymi aetheroleum Tiliae flos Urticae herba All food-producing species For topical use only All food-producing species All food-producing species All food-producing species L 6 0 / 4 4 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 LIST OF PHARMACOLOGICALLY ACTIVE SUBSTANCES USED IN VETERINARY MEDICINAL PRODUCTS FOR WHICH PROVISIONAL MAXIMUM RESIDUE LIMITS HAVE BEEN FIXED ANNEX III Anti-infectious agents Chemotheurapeutics 1. 1. 1. 1. 1. 2. Benzenesulphonamides Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Clorsulon Clorsulon Bovine 50 lg/kg Muscle 150 lg/kg 400 lg/kg Kidney Liver Provisional MRLs expire on 1 January 2000 Antibiotics 1. 2. 1. 2. 1. Beta-lactamase inhibitors Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Clavulanic acid Clavulanic acid Bovine, ovine Bovine, ovine, porcine Provisional MRLs expire on 1 July 1999 200 lg/kg Milk 200 lg/kg Muscle 200 lg/kg 200 lg/kg 200 lg/kg Kidney Fat Liver Marker residue Animal species MRLs Target tissues Other provisions 1. 2. 2. Macrolides Pharmacologically active substance(s) Erythromycin MRLs apply to all micro- biological active residues expressed erythro- as mycin equivalent Bovine, ovine Bovine, ovine, porcine, poultry Josamycin Josamycin Poultry Chicken Provisional MRLs expire on 1 June 2000 Provisional MRLs expire on 1 July 2000 40 lg/kg Milk 400 lg/kg Muscle 400 lg/kg 400 lg/kg 400 lg/kg Kidney 200 lg/kg Fat Liver Eggs 200 lg/kg Muscle 200 lg/kg 200 lg/kg 400 lg/kg Kidney 200 lg/kg Fat Liver Eggs 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 4 5 1. 2. 5. Aminoglycosides Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Aminosidine Aminosidine Bovine, porcine, rabbits, chicken 500 lg/kg Muscle 1 500 lg/kg 1 500 lg/kg Kidney Liver Provisional MRLs expire on 1 July 2000 Apramycin Apramycin Bovine For use in non-lactating cattle only Porcine Dihydrostreptomycin Dihydrostreptomycin Bovine, ovine Bovine, ovine, porcine, poultry Gentamicin Gentamicin Bovine Bovine, porcine Neomycin (including framycetin) Neomycin Bovine, ovine, caprine Bovine, ovine, caprine, porcine, chicken, turkey, duck Chicken Fat Liver 1 000 lg/kg Muscle 1 000 lg/kg 10 000 lg/kg 20 000 lg/kg Kidney 1 000 lg/kg Muscle 1 000 lg/kg 1 000 lg/kg 5 000 lg/kg Kidney Skin and fat Liver 200 lg/kg Milk 500 lg/kg Muscle 500 lg/kg 500 lg/kg Fat Liver 1 000 lg/kg Kidney 100 lg/kg Milk 100 lg/kg Muscle 100 lg/kg 200 lg/kg Fat Liver 1 000 lg/kg Kidney 500 lg/kg Milk 500 lg/kg Muscle 500 lg/kg 500 lg/kg Fat Liver 5 000 lg/kg Kidney 500 lg/kg Eggs Provisional MRLs expire on 1 July 1999 Provisional MRLs expire on 1 June 2000 Provisional MRLs expire on 1 June 2000 Provisional MRLs expire on 1 June 2000 L 6 0 / 4 6 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Spectinomycin Spectinomycin Bovine Bovine, porcine, poultry Streptomycin Streptomycin Bovine, ovine Bovine, ovine, porcine, poultry Provisional MRLs expire on 1 July 2000 Provisional MRLs expire on 1 June 2000 200 lg/kg Milk 300 lg/kg Muscle 500 lg/kg 2 000 lg/kg 5 000 lg/kg Kidney Fat Liver 200 lg/kg Milk 500 lg/kg Muscle 500 lg/kg 500 lg/kg Fat Liver 1 000 lg/kg Kidney 1. 2. 6. Quinolones Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Decoquinate Decoquinate Bovine, ovine Enrofloxacin Sum of enrofloxacin and Ovine ciprofloxacin Flumequine Flumequine Bovine, ovine, porcine, chicken Marbofloxacin Marbofloxacin Bovine Salmonidae Provisional MRLs expire on 1 July 2000 Provisional MRLs expire on 1 July 1999 Provisional MRLs expire on 1 January 2000 Provisional MRLs expire on 1 July 2000 500 lg/kg Muscle 500 lg/kg 500 lg/kg 500 lg/kg Kidney Fat Liver 100 lg/kg Muscle 100 lg/kg 300 lg/kg 200 lg/kg Kidney Fat Liver 50 lg/kg Muscle 50 lg/kg Fat or skin and fat Liver 100 lg/kg 300 lg/kg Kidney 150 lg/kg Muscle and skin 150 lg/kg Muscle 50 lg/kg 150 lg/kg 150 lg/kg Kidney 75 lg/kg Milk Fat Liver 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 4 7 Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Porcine 150 lg/kg Muscle 50 lg/kg 150 lg/kg 150 lg/kg Kidney Skin and fat Liver 1. 2. 9. Polymyxins Phamarcologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Colistin Colistin Bovine, ovine Bovine, ovine, porcine, chicken, rabbits Chicken 50 lg/kg Milk 150 lg/kg Muscle 150 lg/kg 150 lg/kg 200 lg/kg Kidney 300 lg/kg Fat Liver Eggs Provisional MRLs expire on 1 July 2000 1. 2. 10. Penicillins Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Penethamate Benzylpenicillin Ovine Porcine Provisional MRLs expire on 1 January 2000 Fat Liver 50 lg/kg Muscle 50 lg/kg 50 lg/kg 50 lg/kg Kidney 4 lg/kg Milk 50 lg/kg Muscle 50 lg/kg 50 lg/kg 50 lg/kg Kidney Fat Liver 1. 2. 11. Florfenicol and related compounds Pharmacologically active substance(s) Florfenicol Marker residue Animal species MRLs Target tissues Other provisions Sum of florfenicol and its metabolites measured as florfenicol-amine Fish 1 000 lg/kg Muscle and skin in natural proportions Provisional MRLs expire on 1 July 2001 L 6 0 / 4 8 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 2. Antiparasitic agents 2. 1. Agents acting against endoparasites 2. 1. 2. Benzimidazoles and pro-benzimidazoles Pharmacologically active substance(s) Albendazole sulphoxide Netobimin Marker residue Animal species MRLs Target tissues Other provisions Bovine, ovine Bovine, ovine, pheasant Bovine, ovine, caprine albendazole, Sum of albendazole sulphoxide, albendazole sulphone, and albendazole 2-amino sulphone, expressed as albendazole Sum of netobimin and albendazole and meta- bolites albendazole measured as 2-amino- benzimidazole sulphone of Provisional MRLs expire on 1 January 2000 Provisional MRLs expire on 31 July 1999 100 lg/kg Milk 100 lg/kg Muscle 100 lg/kg 1 000 lg/kg Fat Liver 500 lg/kg Kidney 100 lg/kg Muscle 100 lg/kg 1 000 lg/kg Fat Liver 500 lg/kg Kidney 100 lg/kg Milk 2. 2. Agents acting against ectoparasites 2. 2. 1. Formamidines Pharmacologically active substance(s) Amitraz Marker residue Animal species MRLs Target tissues Other provisions Sum of amitraz and all metabolites containing the 2,4-DMA moeity, expressed as amitraz Bees 200 lg/kg Honey Provisional MRLs expire on 1 July 1999 2. 2. 2. Iminophenyl thiazolidine derivative Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Cymiazole Cymiazole Bees 1 000 lg/kg Honey Provisional MRLs expire on 1 July 1999 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 4 9 2. 2. 3. Pyretrin and pyrethroids Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Cyfluthrin Cyfluthrin Bovine Provisional MRLs expire on 1 January 2001 10 lg/kg Muscle 50 lg/kg 10 lg/kg 10 lg/kg Kidney 20 lg/kg Milk Fat Liver provisions in Council Further Directive to be 94/29/EC are observed (OJ L 189, 23. 7. 1994, p. 67) 2. 2. 4. Organophosphates Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Azamethiphos Azamethiphos Salmonidae 100 lg/kg Muscle and skin in Provisional MRLs expire on 1 June 1999 natural proportions 2. 2. 5. Acyl urea derivates Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Teflubenzuron Teflubenzuron Salmonidae 500 lg/kg Muscle and skin in Provisional MRLs expire on 1 July 1999 natural proportions 2. 3. Agents acting against endo- and ectoparasites 2. 3. 1. Avermectins Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Moxidectin Moxidectin Equidae 50 lg/kg Muscle 500 lg/kg 100 lg/kg 50 lg/kg Kidney Fat Liver Provisional MRLs expire on 1 January 2000 L 6 0 / 5 0 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s 9. 3. 1 9 9 9 Agents acting on the nervous system Agents acting on the autonomic nervous system 3. 3. 2. 3. 2. 1. b2 sympathomimetic agents Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Clenbuterol hydrochloride Clenbuterol Bovine Indication: parturient cows solely for tocolysis in Equidae Indications: tocolysis and the treatment of respiratory ailments Anti-inflammatory agents 5. 5. 1. Nonsteroidal anti-inflammatory agents 5. 1. 1. Arylpropionic acid derivative Liver 0,1 lg/kg Muscle 0,5 lg/kg 0,5 lg/kg Kidney 0,05 lg/kg Milk 0,1 lg/kg Muscle 0,5 lg/kg 0,5 lg/kg Kidney Liver Provisional MRLs expire on 1 July 2000 Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Carprofen Carprofen Bovine Equidae Provisional MRLs expire on 1 January 2000 Fat Liver 500 lg/kg Muscle 500 lg/kg 1 000 lg/kg 1 000 lg/kg Kidney 50 lg/kg Muscle 100 lg/kg 1 000 lg/kg 1 000 lg/kg Kidney Fat Liver 5. 1. 2. Enolic acid derivates Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions Meloxicam Meloxicam Bovine 25 lg/kg Muscle 60 lg/kg 35 lg/kg Kidney Liver Provisional MRLs expire on 1 January 2000 9. 3. 1 9 9 9 E N O f f i c i a l J o u r n a l o f t h e E u r o p e a n C o m m u n i t i e s L 6 0 / 5 1 L 60/52 EN Official Journal of the European Communities 9. 3. 1999 LIST OF PHARMACOLOGICALLY ACTIVE SUBSTANCES FOR WHICH NO MAXIMUM LEVELS CAN BE FIXED ANNEX IV Pharmacologically active substance(s) Aristolochia spp. and preparations thereof Chloramphenicol Chloroform Chlorpromazine Colchicine Dapsone Dimetridazole Metronidazole Nitrofurans (including furazolidone) Ronidazole