Woolly hair autosomal recessive
# Woolly hair autosomal recessive

Woolly hair autosomal recessive is a rare hereditary hair disorder characterized by sparse, short, curly hair.

## Signs/symptoms

The scalp hair is sparse, short and curly. It grows slowly and stops growing after a few inches.

## Genetics

This condition may be part of a more complex syndrome or an isolated mutation.

Isolated cases are due to mutations in the lipase member H (LIPH), lysophosphatidic acid receptor 6 (LPAR6) or keratin 2A (KRT2) genes. Isolated cases are inherited in an autosomal recessive fashion.

## Epidemiology

This is rare disorder. Precise estimates of its prevalence are not known.

## Diagnosis

This is made by light microscopy. A number of structural anomalies are visible under light microscopy including trichorrhexis nodosa and tapered ends.

### Differential diagnosis

* Cardiofaciocutaneous syndrome
* Naxos disease
* Palmoplantar keratoderma and cardiomyopathy syndrome

## Treatment

There is no treatment for this condition known at present.

## Prognosis

In isolate cases life expectancy is normal and there are no other related problems.

As part of another syndrome this will depend on the other features of the syndrome.

