5-(Nonyloxy)tryptamine
# 5-(Nonyloxy)tryptamine

5-(Nonyloxy)tryptamine is a tryptamine derivative which acts as a selective agonist at the $5-HT_{1B}$ receptor. Increasing the O-alkoxy chain length in this series gives generally increasing potency and selectivity for $5-HT_{1B},$ with highest activity found for the nonyloxy derivative, having a $5-HT_{1B}$ binding affinity of 1.0 nM, and around 300-fold selectivity over the related $5-HT_{1A}$ receptor.

