2021 FINA World Swimming Championships (25 m) – Men's 4 × 100 metre medley relay
# 2021 FINA World Swimming Championships (25 m) – Men's 4 × 100 metre medley relay

The Men's 4 × 100 metre medley relay competition of the 2021 FINA World Swimming Championships (25 m) was held on 21 December 2021.

## Records

Prior to the competition, the existing world and championship records were as follows.

| World record | Russia (RUS) | 3:19.16 | Saint Petersburg, Russia | 20 December 2009 |
| - | - | - | - | - |
| Competition record | United States (USA) | 3:19.98 | Hangzhou, China | 16 December 2018 |

The following new records were set during this competition:

| Date | Event | Name | Nation | Time | Record |
| - | - | - | - | - | - |
| 21 December | Final | Lorenzo Mora (50.34) Nicolò Martinenghi (55.94) Matteo Rivolta (48.43) Alessandro Miressi (45.05) | Italy | 3:19.76 | CR |

## Results

### Heats

The heats were started at 10:09.

| Rank | Heat | Lane | Nation | Swimmers | Time | Notes |
| - | - | - | - | - | - | - |
| 1 | 1 | 4 | Russian Swimming Federation | Pavel Samusenko (50.48) Alexander Zhigalov (57.74) Roman Shevliakov (50.70) Vladislav Grinev (46.09) | 3:25.01 | Q |
| 2 | 2 | 5 | Italy | Thomas Ceccon (50.96) Nicolò Martinenghi (56.90) Alberto Razzetti (50.48) Lorenzo Zazzeri (47.24) | 3:25.58 | Q |
| 3 | 2 | 4 | United States | Hunter Tapp (52.52) Will Licon (57.40) Trenton Julian (49.25) Zach Apple (46.80) | 3:25.97 | Q |
| 4 | 1 | 5 | Brazil | Guilherme Guido (50.31) Caio Pumputis (58.20) Nicholas Santos (50.46) Breno Correia (47.33) | 3:26.30 | Q |
| 5 | 1 | 2 | Netherlands | Kenzo Simons (54.10) Arno Kamminga (56.17) Nyls Korstanje (50.08) Luc Kroon (46.91) | 3:27.26 | Q, NR |
| 6 | 1 | 3 | France | Mewen Tomac (50.99) Antoine Viquerat (57.14) Thomas Piron (51.85) Jordan Pothain (47.54) | 3:27.52 | Q |
| 7 | 1 | 1 | Norway | Markus Lie (51.22) André Grindheim (58.68) Tomoe Hvas (50.42) Nicholas Lia (47.27) | 3:27.59 | Q, NR |
| 8 | 2 | 6 | Lithuania | Danas Rapšys (52.04) Andrius Šidlauskas (58.48) Deividas Margevičius (50.75) Simonas Bilis (47.91) | 3:29.18 | Q |
| 9 | 2 | 7 | Turkey | Berke Saka (52.62 ) Emre Sakçı (58.03) Rasim Oğulcan Gör (51.56) Baturalp Ünlü (48.03) | 3:30.24 | |
| 10 | 2 | 3 | China | Song Yukuan (53.32) Qin Haiyang (58.00) Wang Changhao (51.14) Pan Zhanle (47.86) | 3:30.32 | |
| 11 | 2 | 1 | Israel | Yakov Toumarkin (51.99) Kristian Pitshugin (58.67) Eitan Ben Shitrit (52.45) Denis Loktev (47.64) | 3:30.75 | NR |
| 12 | 1 | 8 | Egypt | Mohamed Samy (52.55) Youssef El-Kamash (59.71) Youssef Ramadan (50.89) Abdelrahman Sameh (47.68) | 3:30.83 | NR |
| 13 | 1 | 6 | South Korea | Won Young-jun (52.82) Moon Jae-kwon (58.31) Moon Seung-woo (52.86) Lee Ho-joon (48.88) | 3:32.87 | |
| 14 | 1 | 0 | Hong Kong | Lau Shiu Yue (53.61) Michael Ng (1:01.93) Ho Tin Long (53.17) Cheuk Ming Ho (48.22) | 3:36.93 | NR |
| 15 | 2 | 9 | Vietnam | Trần Hưng Nguyên (53.48) Phạm Thanh Bảo (59.95) Hồ Nguyễn Duy Khoa (54.47) Nguyễn Hữu Kim Sơn (50.66) | 3:38.56 | |
| | 1 | 7 | Bulgaria | | DNS | |
| | 2 | 0 | Slovakia | | DNS | |
| | 2 | 2 | Austria | | DNS | |
| | 2 | 8 | Singapore | | DNS | |

### Final

The final was held at 19:50.

| Rank | Lane | Nation | Swimmers | Time | Notes |
| - | - | - | - | - | - |
| | 5 | Italy | Lorenzo Mora (50.34) Nicolò Martinenghi (55.94) Matteo Rivolta (48.43) Alessandro Miressi (45.05) | 3:19.76 | CR, NR |
| | 3 | United States | Shaine Casas (50.44) Nic Fink (55.27) Trenton Julian (49.36) Ryan Held (45.43) | 3:20.50 | |
| | 4 | Russian Swimming Federation | Kliment Kolesnikov (49.47) Danil Semianinov (57.06) Andrey Minakov (48.81) Aleksandr Shchegolev (45.31) | 3:20.65 | |
| 4 | 6 | Brazil | Guilherme Guido (50.16) Caio Pumputis (57.36) Vinicius Lanza (49.62) Gabriel Santos (46.43) | 3:23.57 | |
| 5 | 1 | Norway | Markus Lie (51.00 NR) André Grindheim (57.73) Tomoe Hvas (49.96) Nicholas Lia (46.94) | 3:25.63 | NR |
| 6 | 2 | Netherlands | Stan Pijnenburg (53.61) Arno Kamminga (56.14) Nyls Korstanje (50.48) Luc Kroon (46.36) | 3:26.59 | NR |
| 7 | 8 | Lithuania | Danas Rapšys (51.91) Andrius Šidlauskas (58.30) Deividas Margevičius (50.90) Simonas Bilis (47.84) | 3:28.95 | |
| | 7 | France | Mewen Tomac (50.66) Antoine Viquerat Thomas Piron Maxime Grousset | DSQ | |
