2021 FINA World Swimming Championships (25 m) – Men's 4 × 50 metre freestyle relay
# 2021 FINA World Swimming Championships (25 m) – Men's 4 × 50 metre freestyle relay

The Men's 4 × 50 metre freestyle relay competition of the 2021 FINA World Swimming Championships (25 m) was held on 19 December 2021.

## Records

Prior to the competition, the existing world and championship records were as follows.

| World record | United States (USA) | 1:21.80 | Hangzhou, China | 14 December 2018 |
| - | - | - | - | - |
| Competition record | United States (USA) | 1:21.80 | Hangzhou, China | 14 December 2018 |

## Results

### Heats

The heats were started at 09:30.

| Rank | Heat | Lane | Nation | Swimmers | Time | Notes |
| - | - | - | - | - | - | - |
| 1 | 1 | 4 | Italy | Leonardo Deplano (21.49) Alessandro Miressi (21.12) Manuel Frigo (21.39) Lorenzo Zazzeri (20.95) | 1:24.95 | Q |
| 1 | 2 | 5 | Russian Swimming Federation | Vladimir Morozov (21.33) Daniil Markov (21.47) Vladislav Grinev (21.01) Aleksandr Shchegolev (21.14) | 1:24.95 | Q |
| 3 | 1 | 1 | United States | Zach Apple (21.62) Hunter Tapp (21.53) Kieran Smith (21.20) Tom Shields (21.26) | 1:25.61 | Q |
| 4 | 2 | 4 | Netherlands | Stan Pijnenburg (21.52) Kenzo Simons (21.14) Thomas Verhoeven (22.04) Thom de Boer (21.00) | 1:25.70 | Q |
| 5 | 1 | 7 | China | Zhang Zhoujian (21.82) Wang Changhao (21.22) Pan Zhanle (21.60) Yang Jintong (21.94) | 1:26.58 | Q, NR |
| 6 | 2 | 7 | Belgium | Jasper Aerents (21.42) Jérôme Emo (22.00) Sebastien De Meulemeester (21.76) Thomas Thijs (21.64) | 1:26.82 | Q |
| 7 | 1 | 6 | Switzerland | Roman Mityukov (22.27) Thomas Hallock (21.74) Antonio Djakovic (21.60) Noè Ponti (21.44) | 1:27.05 | Q |
| 8 | 2 | 8 | Lithuania | Danas Rapšys (21.92) Simonas Bilis (21.15) Andrius Šidlauskas (22.23) Deividas Margevičius (21.98) | 1:27.28 | Q |
| 9 | 2 | 1 | South Korea | Hwang Sun-woo (21.72 NR) Kim Woo-min (22.21) Won Young-jun (22.20) Lee Ho-joon (22.43) | 1:28.56 | NR |
| 10 | 2 | 2 | Hong Kong | Ng Cheuk Yin (22.45) Ian Ho (20.96) Ng Yan Kin (23.10) Cheuk Ming Ho (22.53) | 1:29.04 | NR |
| 11 | 1 | 3 | Turkey | Emre Sakçı (21.61) Doruk Tekin (22.97) Rasim Oğulcan Gör (22.35) Metin Aydın (22.49) | 1:29.42 | |
| 12 | 2 | 6 | Vietnam | Hồ Nguyễn Duy Khoa (23.83) Nguyễn Hữu Kim Sơn (23.76) Trần Hưng Nguyên (23.43) Phạm Thanh Bảo (25.11) | 1:36.13 | |
| | 1 | 5 | Poland | Paweł Juraszek (21.93) Jakub Majerski Kacper Stokowski Marcin Cieślak | DSQ | |
| | 1 | 2 | Slovakia | | DNS | |
| | 2 | 3 | Great Britain | | DNS | |

### Final

The final was held at 18:00.

| Rank | Lane | Nation | Swimmers | Time | Notes |
| - | - | - | - | - | - |
| | 4 | Italy | Leonardo Deplano (21.37) Lorenzo Zazzeri (20.42) Manuel Frigo (21.21) Alessandro Miressi (20.61) | 1:23.61 | |
| | 5 | Russian Swimming Federation | Andrey Minakov (21.14) Vladimir Morozov (20.61) Vladislav Grinev (20.72) Aleksandr Shchegolev (21.28) | 1:23.75 | |
| | 6 | Netherlands | Jesse Puts (21.30) Stan Pijnenburg (20.91) Kenzo Simons (21.16) Thom de Boer (20.41) | 1:23.78 | |
| 4 | 3 | United States | Ryan Held (20.72) Shaine Casas (20.73) Zach Apple (21.06) Kieran Smith (21.30) | 1:23.81 | |
| 5 | 2 | China | Zhang Zhoujian (21.67) Wang Changhao (20.88) Pan Zhanle (21.14) Yang Jintong (21.81) | 1:25.50 | NR |
| 6 | 7 | Belgium | Jasper Aerents (21.60) Jérôme Emo (22.16) Sebastien De Meulemeester (21.56) Thomas Thijs (21.62) | 1:26.94 | |
| 7 | 8 | Lithuania | Danas Rapšys (21.94) Simonas Bilis (21.33) Andrius Šidlauskas (22.01) Deividas Margevičius (21.81) | 1:27.09 | |
| 8 | 1 | Switzerland | Roman Mityukov (22.31) Thomas Hallock (21.43) Antonio Djakovic (21.61) Noè Ponti (21.75) | 1:27.10 | |
