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1NO. O. 1 SD lCHARD NOKlH, No. 8, Government sl. 1Aand 45, Commerce street, neal St. lrancis- ia,po ter of French and Englsh l,ltgs, { hemsu,, aad PeriiimeTy, and Wholesale and Retail Deal, m Drugs, Paints, Medicines, Oils, Gass, and I.,e >tuils, No. 35, Government, near Royal, and 4o, Commerce., near Si. Francis street, miOi nls his friends and the public generally, that he has taken t- store No. 45, Common street, (iwo dools tIom Si Francs.) east side, where m conneNIon With hls stofe No. 35, Governments he intends keeping an extensive assortment of all articles ln his line ul lu- siness. He does not expect, much less hope, iol more encouragement and support than he has hher to received, without claiming for himself the metd of nefIt. lie Will at all times use his best enheas render satisfaction all who may iasoi h,s establishment With their patronage. As he Is well aware how highly important it Is tor Physicians and ianilies obtain medicines in their pure state, the public may rest assured in obtaining Lure and iresh medicines. He Is receiving, and will continue tU cel,e, by the latest arrivals, aIge, fresh, and peror assortment of American, English, and Elenrh Medicines, selected wIth the greatest care. The assortment of drugs and family medicines, eomIrs- ing every article of the choises and freshest seie tion in the line, from the best European and A. lHerican manuiaclures.

 He also will keep hand select assortment fresh Garden amp Field Seeds, Beens and Peas

 N. B. Orders frOm the country filled al Ibe shoIl est notice. feb l UAILEK'S FRENCH PILLS.-F300 CHAL- LENGE.-The genuine French Pills against all Qnack Nostrums of the age, for the cure oi f*f

 The Preach Pills are applicable in all cases k.r [, her sex, (warranted flee from Mel culy) and possess great assaptaRes oser the Bakams and all liauid medicines, by beng entirely free from snle anu con seqaeatly do not affect the breah thereby preventing the possibility of discovery while using them.

 Besides this important advantage, they never dsa- gree with the stonach and in the first stages of the disease, they usually effect in n few days with little regard to diet exposure.

 In the most obstinate stages of the disease, they are equally certain, having cured many after every other remedy had failed In short, they have leen so universally successfl that the proprietor challenges any io produce remedy of equal certainty unGer a forfeiture of Three Hundred Dollars.

 ianl2 I.C. DUBOSE x CO, 39 Water st.

 0y- Price, S2 per box, with full directions.

 JUDGE PATTERSON.-Rea the follow ing O frsm Judge Patterson, for thirty years the firsi Judge of the county Tn which lie lives.

 -gsr MIDDLETowN, N. J., March l2. is40. Messrs. Comstock & Co.,, ..

 Gentlernen-You are at liberty to make tech use of the following certificate you deem will nes sub- serve the purposes for which it is intended. L tCERTIrICATE or JUDGE PATTERtoK.1 hereby certify, that my daughter has be, afict- | ed with sick headache for the space of nbou, 20 years-the attack occurring once in about eeks, frequently lasting 24 hours, during which lime the Paroxy.ms have been SO severe, as appaientiy soon to deprive her of life. And after having tr, q almost all other remedies in vain, have been indu, cd last resort to try Spohn's Headache kemed, IS sold | by you; and to the great disappointment ah joy of herse and all her friends found very material relic from the first dose of the medicine. She has follow ed up the directions with the article, and in every case when, attack threatened has found lmne dlats reliet, until she is near permanently cmed.- The attacks are very seldom, and disappea, a- most immediately after taking the quantity oiiected. | A hope that ethers may be beneitted , the use oi this truly inv sauable medicine, has induced | yon the above, and reniain your obedent servant, 'JEHU PATTERSON, Judge of the Count oi | P. | j | .i=si e@i i4 y.A COMSTOCk < O., Wholesale Druggists, 2 Fletcher st. New lok. l. Sold by - l. C. DuBOSE x. co, Agents,

 and by Drs Maynard, Hammond, and Gates, sloee Il jan 28 TO

 KaITCHEN'S PATENT PREPARED IO- lA C0A.--A supply of the above original and lru-

 y. vslabe preparation of Cocoa long and ayoiabl, knswn ths public, just received direct from the proprietor sad for sale by the undersigned. Among Fl other highly hatteripg testimonials ot its superior quality and usefulness, are found the following. II "J. Kitchen left with me soine of his P. Cocoa and on trial find it very superior article, and rerom

 mend it's adoption for tamil, ase." e,i Fl ss. N'. j" Dr. WILLIAM THOMAS, lntI have tried your P. Cocoon and consider ii dec- decly superior any have used before in my anl- I y-" ..., ,-.,t4.,,, f f. Dr. JNO. COOPER.

 a"I concur in the foregoing staiements." ,l.., l3A Ean tlss'al ..l' Dr. D. HossAcK, L. ~I have drank of Kitchens F. Cocoa an, recoln- . araton of Cocoa exanteit possesses less of the oii- aginous nature of Chocolate, therefore less liable becoge offensive to the coayalescent and able for the healthy. .,,, .an1. t ID. BLoss!

 For sale by I. e. DuBosE $ co. x

 eianl4 "113al late DuBose < Rolf, 39 Water st. .DAtiGING, ROPE < TWINE.-The subscri-

 ID Der. having been appointed AGENT for the

 MAysyiLLE MANUfAeTpRIne,iC Co. will be con constantly supplied and fill orders for Bagging and Rope to any extent, on favorable terms, The quality is unsurpassed D, any Factory in the western country. #.,.,,-t,.ff !ot3.I, ,3 ftiti .sfs ~

 Daily expected direct from the Factory .s.a s300 pieces Bagglng, 300 coils Rope ,, na 3ii qsl4 FRANKLIN W. MCCOY,

 an27 lo9Kmo l.. .l.l ia D 69 Commerce st' lil LUST RECEIvED.--The Life, Adventures an and ! O Opinions of David Tho. Hines, of South Caro ,rl, master of arts, and sometimes doctor of medi ,, cines, alias, Dr, Hamilton, Col Hamilton, Dr. Hay

 mes, Col Hayne, cl &c. &c. in series of letters td

 his friends, written by himself \ @ssrhe good old rule s s 2 a

 ''" Suffceth ms,--the simple plan, .. | sas., That they should take, who have the power, ' IL And they should keep who can, Wordsuorfh AFor sale by ,i go1qmsns K RANDALL, : Ebl6 n l, Bookseller, A Water sts IuyALKER ON, IsTERMARRIAGE.-a. {,

 W DOUBLEDAY & SEARS, 50 Dauphn-s, Have received Walker on lntermarriage; or ih mode in which, and the causes why, Beauty, Heat and InteIect, result from certain auaions. deform,

 disease and insanity from others, with eight illusira

 tive dfawags.h fp'i7A hr'' - ian2S LNOR SALE.-l0, ,OOpp pes of superior, heavy, 4

 " inch Dundee Bagging, manufactured expressl

 for this market. part of the lo is made in imiia

 tion of the Kentucky Bagging, ind quite equal to

 in quality. We invite the attention of the Planel

 and the trade to this article Also, 80 coils Russia

 Rope, for sale by D 800 ssu- AsPOPE SON,

 dec29 147tfi f t..f 57 Commerce 70 IOMPOUNDe SYRUP OF LlvERWORT : " (Hspatiea Tfilsba.)-For the cure of Pulmoa ,, y and Hepac affections, Coughs, Colds, Consuml T. ton, Spitiing of Blood, Sc. The reputation whc this article .iyerwort) has obtained in the treafmer 10 of Consumptions, Splitting of Bood Liver Con paints Coughs, c. and the great uncertainty her mus: always be in the preparation of decoctions t |. mode in which this plant has been usually admin. n ,ered by persons ignorant of Pharmaceutical Man, - puations, has led us make concentrated Con