E,ou fRs Ns.O. York Stap, Anr. l2.
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 Ihere had been much rain all day. the vast uuantity of combustible materials which were in this part of the city. being chiefly printing and publishing establishments of dif- Ferent newspapers, paper warehouses and bookstores, caused the flames to spread with | frightfOI rapidily. The extreme height Of Inc buildings also, the confined rooms and passages of the stores, the hour at which the fire broke out, and the general narrOwness of the streets, all contributed to give more ter rible character to this awful cOnfagration.

 We lament to state that there were several yalu able lives lost. 1t is te be regretted. where the practice exists so generally of the uppermOst stories for sleeping, as affOrding the purest air, that people do not take the precautiOn of having safety ladder in their rooms. Until, however, there is a radical change in the false and flimsy mode of building houses prevalent in our city, we may expect a repetition of such scenes as were exhibited this morning. The rpins are still smoking, and present a scene of devasta- ton which was seldom or never befOre wit messed incur city. It is impossible to-day to

 fix the immense amount of property destroy ed or the proportion insured. 8ar

 The following are the particulars as far as we are enabled to procure them for to. day:

 

 I15 Fulton, five story buildings, occupied as book. stores, printing offices. and hook binde- ries,) all totally destroyed. man named

 Blanchard jumped from the 4th story of ll3, with his clothes on fire, and died in about five minutes after striking the ground. This may have been considered rash, but it must be recollected that the fire broke out at an early hour in the morning. when all were in their beds-that the buildings are extremely high. and the rooms and passages being small and filled with smoke, rendered escape by the staircase next to impossible. Mr. Scott, Mr. c. Baldwin, Messrs. Carlise and Wyatt, Printers, who slept in the same building, were buried in the ruins. Nos. 1O7, Mr. JnO. Budd. cabinet maker-109, Mrs. Prentiss' boarding house; and TIT, occupied by Abm. Bell & Co.-all totally destroyed,

 On the Opp0site side of Fulton, No. 1l6, Gale. Wood & Hughes. silversmiths-ll8, Joseph & s. Hall. gunsmiths-il4. three sto- ry brick-aiI totally destroyed-l12, 6 sto- ry) partially; also the 5 story brick house corner of Dutch-street, partially.

 Aan-street.-NO. S2, 1st story, Old COun- tryman office 2d and Sd, bindery. and 4th and 9th, Wm. E. Dean, printer-hnilding en- tirely destroyed. No. S4, story, totally de- strOyed-occupied in basement as 3 press

 

 derson, value $SOOO-insured Sl5OO on that and printing office in Sd story, which alone was valued at $i5OO. First story of same building. Transcript paper; publication ma terials mostly saved. 2d story, Jefsrsonian materials partly saved. 4th story, furniture of the old Catholic church. temporarily de- posted there, entirely destroyed. ,5th story, printing office of the New Yorker, (Greely & Winchester.) Their total loss is about S25O0, having saved, out of the general wreck, only few papers. Nos. S8 and 40, story brick, entirely destroyed. On the opposite side of the street. No. S2, a 5 story brick, occupied as a paper warehouse below, and as bindery in the stOry-N0. SS. Occu- pied by Mr. Scott, printer. Mr. Redfeld, ste reotype founder, and others--both destroyed. This was also the printing office of the Mirror. 5000 copies of which, prepared for the present week. were destroyed, a small proportion only of which was insured. Also the Catholic church, and story brick ad- jOining. aaa8xn g'H sj

 Nassu0- eet.-Ex attending to Nassau. street, destroying Nos. lO2, lO4, l06, lO8, I1O. Ill. ll2. IA, ll6, 1l8, l2O. ll4,3ll6 and ll8 ail occupied as Book and Paper stores, and 1O6, los. 8 story brick-llO, IF, story brick, all totally destroyed. ll4, l16. 118, were att story brick. 122, l24, l story brick-Lawyers' offices lower part {; | lpPer part dwellings,. l22, owned by E. ! Neyman-insured; occupied by Mrs. Ball, ! ls Boarding house, and lower floor by J. | }. Hart. P. Barnes. and A. Kiriland. Aitor- lies. l24, lower foor, E. Brown and F. A. 1 ralImajge. AttorDies. l2O, occupied by [ Mr. Edie, Baker. . llO Jno. Campbell & Go. ! Paper WarehOuse,--w extended into % | lnn street. No. III Nassau street, small wo story frame building, adjoining the Mir pr Office. occupied as Srgar store,-par- ally destroyed. o .@ stl1

 There has not been such a fire in thirty ve years !-There were 30 or 40 valuable lrge buildings destroyed. The engines col .cted as early as could be expected. consid- ring the hour of the night. But there seem ! to be an apathy in the owners and occu- iers. each believing his building was fire roof and safe. Therefore the loss was im- 'ense. The very .unsubstantial manner in hich most of houses were built, ,-their walls , Ihin as lO tumble nearly by their own made the fremen cautious } entering them. A new system of build 6 must be devised. No insurance cOmpa- must risk their funds On houses of this 'o-work character. especially if over fonr Iories. |,

 Itcenty- one of the finest printing offices in own--eteten binderies, including shirieea pub InnIg establishments of ne,cspapers-.fUe of 'n'cn were large. and eight penny papers ave been among the property destroyed.

 U IS, iact. that the greater portion of the ,rge nlgn oul!diDgs of brick were perfect