Swimming at the 1999 Pan American Games – Women's 4 × 100 metre medley relay
# Swimming at the 1999 Pan American Games – Women's 4 × 100 metre medley relay

The women's 4 × 100 metre medley relay competition of the swimming events at the 1999 Pan American Games took place on August 6 at the Pan Am Pool. The last Pan American Games champion was the United States.

## Results

All times are in minutes and seconds.

| KEY: | q | Fastest non-qualifiers | Q | Qualified | GR | Games record | NR | National record | PB | Personal best | SB | Seasonal best |
| - | - | - | - | - | - | - | - | - | - | - | - | - |

### Final

The final was held on August 6.

| Rank | Name | Nationality | Time | Notes |
| - | - | - | - | - |
| | Denali Knapp Staciana Stitts Karen Campbell Tammie Spatz | United States | 4:06.08 | GR |
| | Kelly Stefanyshyn Lauren van Oosten Jessica Deglau Laura Nicholls | Canada | 4:08.73 | |
| | Fabíola Molina Tanya Schuh Patrícia Comini Tatiana Lemos | Brazil | 4:15.00 | |
| 4 | - - - - | Cuba | 4:24.15 | |
| 5 | - - - - | - | - | |
| 6 | - - - - | - | - | |
| 7 | - - - - | - | - | |
| 8 | - - - - | - | - | |
