AP4B1
# AP4B1

AP-4 complex subunit beta-1 is a protein that in humans is encoded by the AP4B1 gene.

## Function

The heterotetrameric adaptor protein (AP) complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways. AP4 is composed of 2 large chains, beta-4 (AP4B1, this protein) and epsilon-4 (AP4E1), a medium chain, mu-4 (AP4M1), and a small chain, sigma-4 (AP4S1)

## Interactions

AP4B1 has been shown to interact with AP4M1.

## Clinical relevance

AP4-complex-mediated trafficking plays a crucial role in brain development and functioning.

