Alpha-5 beta-1
# Alpha-5 beta-1

$α_5β_1,$ also known as the fibronectin receptor, is an integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. It is composed of $α_5$ (ITGA5/CD49e) and $β_1$ (ITGB1/CD29) subunits. It is the primary receptor for fibronectin. The interaction of VLA-5 with fibronectin plays an important role in regulating inflammatory cytokine production by human articular chondrocytes (From the Cell Migration Gateway ITGA5 ITGB1).

$α_5β_1-integrin$ is transported inside the cell by the kinesin KIF1C, a kinesin-3 organelle transporter that walks along microtubules.

