Norman Maclean (biologist)
# Norman Maclean (biologist)

Norman Maclean is an Emeritus Professor of Genetics at The University of Southampton. Besides genetics he has worked in wildlife conservation and river management. He has been a Director of the Test and Itchen Association, and a panel member of the European Food Safety Authority. He is an elected Fellow of the Royal Society of Biology and the Linnaean Society. Served as the editor of the Molecular and Cell Science section of the Journal of Fish Biology, and also on editorial boards of other journals in the past. Norman was also a Trustee of Marwell Wildlife Park for many years, and served as its Honorary Scientific Advisor.

Maclean has authored, co-authored and edited over a dozen textbooks and reference books in genetics and cell biology. Between 1984 and 1991 he edited an annual review entitled 'Oxford Surveys on Eukaryotic Genes' (published by Oxford University Press) and most recently edited Silent Summer (Cambridge University Press, 2010). His most recent book A Less Green and Pleasant Land (Cambridge University Press, 2015) was published in early 2015.

## Biography

Maclean was born in 1932 in Edinburgh, Scotland. He was educated at George Heriot's School before going on to obtain a Scottish Diploma in Agriculture at Edinburgh University. Changing track he graduated with a 1st Class Honours in Zoology, and later completed his PhD on ribosome/messenger RNA specificity. Following the completion of his doctorate, Norman spent a year at Rockefeller University, New York as a Sir Henry Wellcome fellow.

Maclean married Jean Kay Smith in 1962. Jean has worked as a medical general practitioner for most of her married life, and together they have two children; Lorna, born in 1965, and Gavin born in 1967

Although reared in a Protestant sect called the 'Exclusive Brethren'; Maclean is an active member of Humanists UK and currently serves as a chair of the local branch.

Maclean began his career as a lecturer at the University of Southampton at the [then] Department of Zoology under the headship of Professor Leslie Brent, was later promoted to a personal chair in Genetics, and eventually went on to become Head of the Department of Biology. During his career he has been a visiting fellow and professor at Universities including; the University of California at Davis; the University of Dalhousie, Canada; the Institute of Hydrobiology, Wuhan, China; the Oceanographic Institute, Cumana, Venezuela; the Institute of Cell Biology, Moscow; and the Biotechnology Institute, Godollo, Hungary.

Norman's entry in "Who's Who" lists his hobbies and interests as: Tennis, Fly Fishing, Gardening and Reading

## Scientific career

Maclean's career began with research attempts to understand the developmental switching of globin genes. In the vast majority of vertebrates there are distinct embryonic, foetal and adult globins. His early work was directed at trying to reactivate foetal globin expression, chiefly working with the amphibian Xenopus and chickens. He was, however, unsuccessful in this project; and indeed the problem remains largely unsolved until the present.

Moving on and with the advent of molecular genetics and the availability of cloned gene sequences, Maclean worked – for a time – with Professor Steve Wratten on the use of DNA fingerprinting in understanding aphid infections of cereal crops. For a few years he also collaborated with Dr David Oscier (a medical consultant at Bournemouth Hospital) on the haematological disease of polycythaemia.

Maclean is best known for his pioneering work on transgenic fish, along with his friend and colleague Zuoyan Zhu. Using rainbow trout (Oncorhynchus mykiss), zebrafish (Danio rerio) and tilapia; he used molecular methods to study gene regulation in fish, and was successful in producing growth-enhanced transgenic tilapia for use in the third world. He also collaborated with Aquagene in the United States in producing transgenic tilapia expressing human factor VII (a clotting factor) in their livers.

