Endonuclease/Exonuclease/phosphatase family
# Endonuclease/Exonuclease/phosphatase family

Endonuclease/Exonuclease/phosphatase family is a structural domain found in the large family of proteins including magnesium dependent endonucleases and many phosphatases involved in intracellular signaling.

## Examples

* AP endonuclease proteins EC 4.2.99.18,
* DNase I proteins EC 3.1.21.1,
* Synaptojanin, an inositol-1,4,5-trisphosphate phosphatase EC 3.1.3.56
* Sphingomyelinase EC 3.1.4.12
* Nocturnin, an NADPH 2' phosphatase

## Subfamilies

* Inositol polyphosphate related phosphatase InterPro: IPR000300

## Human proteins containing this domain

2'-PDE; 2-PDE; ANGEL1; ANGEL2; APEX1; APEX2; CCRN4L; CNOT6; CNOT6L; DNASE1; DNASE1L1; DNASE1L2; DNASE1L3; INPP5A; INPP5B; INPP5D; INPP5E; INPPL1; KIAA1706; OCRL; PIB5PA; SKIP; SMPD2; SMPD3; SYNJ1; SYNJ2; TTRAP; Nocturnin;

