P-Phenetidine
# P-Phenetidine

p-Phenetidine (4-ethoxyaniline) is a chemical compound with the molecular formula $C_8H_{11}NO.$ It is one of the three isomers of phenetidine. It is used as an intermediate in the synthesis of pharmaceutical drugs, dyes, and the sweetener dulcin.

p-Phenetidine is a metabolite of the pharmaceutical drugs bucetin and phenacetin and of the preservative ethoxyquin. It is also used as a chemical intermediate in the manufacture of bucetin, phenacetin, ethoxyquin, and phenacaine.

p-Phenetidine has high renal toxicity and it is believed to be responsible for the adverse effects that led to the withdrawal of phenacetin and bucetin from pharmaceutical use. p-Phenetidine is also a possible mutagen.

