Mainframe (disambiguation)
# Mainframe (disambiguation)

A mainframe computer is a type of large data processing system.

Mainframe may also refer to:

## Fictional entities

* Mainframe (comics), several Marvel Comics characters
* Mainframe (G.I. Joe), a character in the G.I. Joe universe
* Mainframe, a character from the game Gunman Chronicles
* Mainframe, the city in the animated series ReBoot
* Tina "Mainframe" Cassidy, a character from the animated TV series COPS
* Mainframe, a character in Gene Wolfe's series of novels The Book of the Long Sun
