Region 2
# Region 2

Region 2 or Region II may refer to:

* Region 2, Northwest Territories (Canadian census)
* The Midwest of the US (American census)
* Former Region 2 (Johannesburg), an administrative district in Johannesburg, South Africa, from 2000 to 2006
* Antofagasta Region, Chile
* Cagayan Valley (Region II), Philippines
* ITU Region 2, consisting of the Americas
* One of the DVD regions
* One of the health regions of Canada, managed by Horizon Health Network
* One of the regions of Iran
