Sam Hughes (disambiguation)
# Sam Hughes (disambiguation)

Sam Hughes (1853–1921) was a Canadian soldier and politician.

Sam, Sammy, or Samuel Hughes may also refer to:

* Sam Hughes (American football) (born 1970), American football player
* Sam Hughes (fighter) (born 1992), American mixed martial artist
* Sam Hughes (footballer), English footballer
* Sam Hughes (Manitoba politician) (1873–1940)
* Sam Hughes (musician) (1824–1898), ophicleide player
* Sammy Hughes (footballer) (died 2011), footballer from Northern Ireland
* Sammy T. Hughes (1910–1981), baseball player
* Samuel Hughes (judge) (1913–2002), Canadian judge, Chairman of the Hughes Inquiry
* Samuel Hughes (Quaker) (1785–1856), member of the Children of Peace and politician in Upper Canada
* Samuel Hughes (rugby league) (born 2001), Australian rugby league player
* Samuel C. Hughes (1829–1917), American businessman and politician
* qntm (born 1983), British programmer and science fiction author
