List of Cash Box Best Sellers number-one singles of 1951
# List of Cash Box Best Sellers number-one singles of 1951

These are the songs that reached number one on the Top 40 Best Sellers chart (expanded to the Top 50 as of October 13) in 1951 as published by Cash Box magazine. Artists were not specified in the charts of this period so songs may represent more than one version. The artist who most popularized each song is listed.

| Issue date | Song | Artist |
| - | - | - |
| January 6 | "Tennessee Waltz" | Patti Page |
| January 13 | "Tennessee Waltz" | Patti Page |
| January 20 | "Tennessee Waltz" | Patti Page |
| January 27 | "Tennessee Waltz" | Patti Page |
| February 3 | "Tennessee Waltz" | Patti Page |
| February 10 | "My Heart Cries For You" | Guy Mitchell |
| February 17 | "My Heart Cries For You" | Guy Mitchell |
| February 24 | "My Heart Cries For You" | Guy Mitchell |
| March 3 | "Be My Love" | Mario Lanza |
| March 10 | "Be My Love" | Mario Lanza |
| March 17 | "Be My Love" | Mario Lanza |
| March 24 | "Be My Love" | Mario Lanza |
| March 31 | "Be My Love" | Mario Lanza |
| April 7 | "If" | Perry Como |
| April 14 | "If" | Perry Como |
| April 21 | "Mockin' Bird Hill" | Patti Page |
| April 28 | "Mockin' Bird Hill" | Patti Page |
| May 5 | "Mockin' Bird Hill" | Patti Page |
| May 12 | "Mockin' Bird Hill" | Patti Page |
| May 19 | "On Top of Old Smoky" | The Weavers |
| May 26 | "Mockin' Bird Hill" | Patti Page |
| June 2 | "On Top of Old Smoky" | The Weavers |
| June 9 | "Too Young" | Nat King Cole |
| June 16 | "How High The Moon" | Les Paul and Mary Ford |
| June 23 | "How High The Moon" | Les Paul and Mary Ford |
| June 30 | "Too Young" | Nat King Cole |
| July 7 | "Too Young" | Nat King Cole |
| July 14 | "Too Young" | Nat King Cole |
| July 21 | "Too Young" | Nat King Cole |
| July 28 | "Too Young" | Nat King Cole |
| August 4 | "Too Young" | Nat King Cole |
| August 11 | "Come On-a My House" | Rosemary Clooney |
| August 18 | "Come On-a My House" | Rosemary Clooney |
| August 25 | "Because of You" | Tony Bennett |
| September 1 | "Sweet Violets" | Dinah Shore |
| September 8 | "Come On-a My House" | Rosemary Clooney |
| September 15 | "Because of You" | Tony Bennett |
| September 22 | "Because of You" | Tony Bennett |
| September 29 | "Because of You" | Tony Bennett |
| October 6 | "Because of You" | Tony Bennett |
| October 13 | "Because of You" | Tony Bennett |
| October 20 | "Because of You" | Tony Bennett |
| October 27 | "Because of You" | Tony Bennett |
| November 3 | "(It's No) Sin" | Eddy Howard |
| November 10 | "(It's No) Sin" | Eddy Howard |
| November 17 | "(It's No) Sin" | Eddy Howard |
| November 24 | "(It's No) Sin" | Eddy Howard |
| December 1 | "(It's No) Sin" | Eddy Howard |
| December 8 | "(It's No) Sin" | Eddy Howard |
| December 15 | "Down Yonder" | Del Wood |
| December 22 | "(It's No) Sin" | Eddy Howard |
| December 29 | "(It's No) Sin" | Eddy Howard |
