List of Cash Box Top 100 number-one singles of 1972
# List of Cash Box Top 100 number-one singles of 1972

These are the singles that reached number one on the Top 100 Singles chart in 1972 as published in Cash Box magazine.

| Issue Date | Song | Artist |
| - | - | - |
| January 1 | "Got to Be There" | Michael Jackson |
| January 8 | "American Pie" | Don McLean |
| January 15 | "Brand New Key" | Melanie |
| January 22 | "American Pie" | Don McLean |
| January 29 | "American Pie" | Don McLean |
| February 5 | "American Pie" | Don McLean |
| February 12 | "Let's Stay Together" | Al Green |
| February 19 | "Let's Stay Together" | Al Green |
| February 26 | "Precious and Few" | Climax |
| March 4 | "Without You" | Nilsson |
| March 11 | "Without You" | Nilsson |
| March 18 | "Heart of Gold" | Neil Young |
| March 25 | "A Horse with No Name" | America |
| April 1 | "A Horse with No Name" | America |
| April 8 | "A Horse with No Name" | America |
| April 15 | "Rockin Robin" | Michael Jackson |
| April 22 | "The First Time Ever I Saw Your Face" | Roberta Flack |
| April 29 | "The First Time Ever I Saw Your Face" | Roberta Flack |
| May 6 | "The First Time Ever I Saw Your Face" | Roberta Flack |
| May 13 | "The First Time Ever I Saw Your Face" | Roberta Flack |
| May 20 | "I'll Take You There" | The Staple Singers |
| May 27 | "I'll Take You There" | The Staple Singers |
| June 3 | "Oh Girl" | The Chi-Lites |
| June 10 | "The Candy Man" | Sammy Davis, Jr. |
| June 17 | "Sylvia's Mother" | Dr. Hook & The Medicine Show |
| June 24 | "Nice to Be with You" | Gallery |
| July 1 | "Song Sung Blue" | Neil Diamond |
| July 8 | "Outa-Space" | Billy Preston |
| July 15 | "Lean on Me" | Bill Withers |
| July 22 | "Lean on Me" | Bill Withers |
| July 29 | "Too Late to Turn Back Now" | Cornelius Brothers & Sister Rose |
| August 5 | "Daddy Don't You Walk So Fast" | Wayne Newton |
| August 12 | "Alone Again (Naturally)" | Gilbert O'Sullivan |
| August 19 | "Alone Again (Naturally)" | Gilbert O'Sullivan |
| August 26 | "Alone Again (Naturally)" | Gilbert O'Sullivan |
| September 2 | "Brandy (You're a Fine Girl)" | Looking Glass |
| September 9 | "I'm Still in Love with You" | Al Green |
| September 16 | "Long Cool Woman in a Black Dress" | The Hollies |
| September 23 | "Back Stabbers" | The O'Jays |
| September 30 | "Black and White" | Three Dog Night |
| October 7 | "Baby, Don't Get Hooked on Me" | Mac Davis |
| October 14 | "Everybody Plays the Fool" | Main Ingredient |
| October 21 | "My Ding-a-Ling" | Chuck Berry |
| October 28 | "My Ding-a-Ling" | Chuck Berry |
| November 4 | "Nights in White Satin" | The Moody Blues |
| November 11 | "Burning Love" | Elvis Presley |
| November 18 | "I Can See Clearly Now" | Johnny Nash |
| November 25 | "I'll Be Around" | The Spinners |
| December 2 | "I'd Love You to Want Me" | Lobo |
| December 9 | "Papa Was a Rollin' Stone" | The Temptations |
| December 16 | "I Am Woman" | Helen Reddy |
| December 23 | "Me and Mrs. Jones" | Billy Paul |
| December 30 | "Me and Mrs. Jones" | Billy Paul |
