List of Cash Box Top 100 number-one singles of 1978
# List of Cash Box Top 100 number-one singles of 1978

These are the number-one singles of 1978 according to the Top 100 Singles in Cash Box Magazine

| Issue date | Song | Artist |
| - | - | - |
| January 7 | How Deep Is Your Love | Bee Gees |
| January 14 | Baby Come Back | Player |
| January 21 | Baby Come Back | Player |
| January 28 | Short People | Randy Newman |
| February 4 | Stayin' Alive | Bee Gees |
| February 11 | Stayin' Alive | Bee Gees |
| February 18 | Stayin' Alive | Bee Gees |
| February 25 | Stayin' Alive | Bee Gees |
| March 4 | (Love Is) Thicker Than Water | Andy Gibb |
| March 11 | Emotion | Samantha Sang |
| March 18 | Night Fever | Bee Gees |
| March 25 | Night Fever | Bee Gees |
| April 1 | Night Fever | Bee Gees |
| April 8 | Night Fever | Bee Gees |
| April 15 | Night Fever | Bee Gees |
| April 22 | Night Fever | Bee Gees |
| April 29 | Night Fever | Bee Gees |
| May 6 | Night Fever | Bee Gees |
| May 13 | If I Can't Have You | Yvonne Elliman |
| May 20 | With a Little Luck | Paul McCartney & Wings |
| May 27 | With a Little Luck | Paul McCartney & Wings |
| June 3 | Shadow Dancing | Andy Gibb |
| June 10 | Shadow Dancing | Andy Gibb |
| June 17 | Shadow Dancing | Andy Gibb |
| June 24 | Shadow Dancing | Andy Gibb |
| July 1 | Shadow Dancing | Andy Gibb |
| July 8 | Shadow Dancing | Andy Gibb |
| July 15 | Baker Street | Gerry Rafferty |
| July 22 | Baker Street | Gerry Rafferty |
| July 29 | Miss You | Rolling Stones |
| August 5 | Miss You | Rolling Stones |
| August 12 | Three Times A Lady | Commodores |
| August 19 | Three Times A Lady | Commodores |
| August 26 | Three Times A Lady | Commodores |
| September 2 | Three Times A Lady | Commodores |
| September 9 | Grease | Frankie Valli |
| September 16 | Boogie Oogie Oogie | A Taste Of Honey |
| September 23 | Boogie Oogie Oogie | A Taste Of Honey |
| September 30 | Boogie Oogie Oogie | A Taste Of Honey |
| October 7 | Kiss You All Over | Exile |
| October 14 | Kiss You All Over | Exile |
| October 21 | Hot Child In The City | Nick Gilder |
| October 28 | Hot Child In The City | Nick Gilder |
| November 4 | Hot Child In The City | Nick Gilder |
| November 11 | MacArthur Park | Donna Summer |
| November 18 | MacArthur Park | Donna Summer |
| November 25 | You Don't Bring Me Flowers | Barbra Streisand & Neil Diamond |
| December 2 | You Don't Bring Me Flowers | Barbra Streisand & Neil Diamond |
| December 9 | You Don't Bring Me Flowers | Barbra Streisand & Neil Diamond |
| December 16 | Le Freak | Chic |
| December 23 | Le Freak | Chic |
| December 30 | Le Freak | Chic |
