Caloosahatchee
# Caloosahatchee

Caloosahatchee may refer to:

* Caloosahatchee River, a river on the southwest Gulf Coast of Florida in the United States
* Caloosahatchee culture, an archaeological culture on the Gulf coast of Southwest Florida that lasted from about 500 to 1750 CE
* Caloosahatchee National Wildlife Refuge, part of the United States National Wildlife Refuge System
* USS Caloosahatchee (AO-98), US Navy ship
