2022 San Luis Open Challenger – Doubles
# 2022 San Luis Open Challenger – Doubles

Marcelo Arévalo and Miguel Ángel Reyes-Varela were the defending champions but only Reyes-Varela chose to defend his title, partnering Nicolás Barrientos. Reyes-Varela successfully defended his title, defeating Luis David Martínez and Felipe Meligeni Alves $7–6^{(13–11)},$ 6–2 in the final.

## Seeds

* Nicolás Barrientos / Miguel Ángel Reyes-Varela (champions)
* Luis David Martínez / Felipe Meligeni Alves (final)
* Andrej Martin / Tristan-Samuel Weissborn (semifinals)
* Gonçalo Oliveira / Divij Sharan (first round)

## Draw

### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

| First round | First round | First round | First round | First round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| 1 | N Barrientos MÁ Reyes-Varela | 6 | 6 | | | | | | | | | | | | | | | |
| WC | S Mochizuki J Shang | 4 | 0 | | 1 | N Barrientos MÁ Reyes-Varela | 6 | 6 | | | | | | | | | | |
| | M Alves E Escobedo | 6 | 6 | | | M Alves E Escobedo | 2 | 4 | | | | | | | | | | |
| | J Clarke P Krstin | 4 | 4 | | | | | | | 1 | N Barrientos MÁ Reyes-Varela | 6 | $7^7$ | | | | | |
| 3 | A Martin T-S Weissborn | 6 | $6^4$ | [10] | | | | | | 3 | A Martin T-S Weissborn | 4 | $6^2$ | | | | | |
| | E Donskoy D Istomin | 1 | $7^7$ | [6] | 3 | A Martin T-S Weissborn | 6 | 6 | | | | | | | | | | |
| | JC Aragone F Mena | 4 | 4 | | | J Eysseric F Gaio | 4 | 4 | | | | | | | | | | |
| | J Eysseric F Gaio | 6 | 6 | | | | | | | | | | | | 1 | N Barrientos MÁ Reyes-Varela | $7^{13}$ | 6 |
| | N Jarry R Quiroz | $6^7$ | 6 | [10] | | | | | | | | | | | 2 | LD Martínez F Meligeni Alves | $6^{11}$ | 2 |
| | J Lenz G Melzer | $7^9$ | 4 | [8] | | N Jarry R Quiroz | 6 | $7^8$ | | | | | | | | | | |
| | B Arias F Zeballos | 7 | 6 | | | B Arias F Zeballos | 3 | $6^6$ | | | | | | | | | | |
| 4 | G Oliveira D Sharan | 5 | 3 | | | | | | | | N Jarry R Quiroz | 4 | 6 | [6] | | | | |
| WC | L Patiño M Sánchez | 2 | 4 | | | | | | | 2 | LD Martínez F Meligeni Alves | 6 | 1 | [10] | | | | |
| | JP Ficovich N Mejía | 6 | 6 | | | JP Ficovich N Mejía | $6^9$ | 6 | [8] | | | | | | | | | |
| | M-A Hüsler E King | 3 | 4 | | 2 | LD Martínez F Meligeni Alves | $7^{11}$ | 2 | [10] | | | | | | | | | |
| 2 | LD Martínez F Meligeni Alves | 6 | 6 | | | | | | | | | | | | | | | |
