List of highest-grossing Filipino films in 2012
# List of highest-grossing Filipino films in 2012

The following are Filipino films that earned at least 50 million pesos in 2012 during their screenings.

| Rank | Film | Production outfit | Film released | Domestic gross |
| - | - | - | - | - |
| 1. | Sisterakas | Star Cinema, Viva Films | December 25 | ₱ 391,000,000 (est.) |
| 2. | The Mistress | Star Cinema | September 12 | ₱ 262,790,230 |
| 3. | This Guy's in Love with U Mare! | Star Cinema, Viva Films | October 10 | ₱ 249,105,182 |
| 4. | One More Try | Star Cinema | December 25 | ₱ 205,000,000 (est.) |
| 5. | ÜnOfficially Yours | Star Cinema | February 15 | ₱ 157,254,200 |
| 6. | Kimmy Dora and the Temple of Kiyeme | Spring Films, Star Cinema | June 13 | ₱ 133,963,009 |
| 7. | Si Agimat, si Enteng Kabisote at si Ako | OctoArts Films, GMA Films | December 25 | ₱ 133,500,000 (est.) |
| 8. | A Secret Affair | Viva Films | October 24 | ₱ 118,424,018 |
| 9. | The Healing | Star Cinema | July 25 | ₱ 104,602,460 |
| 10. | Tiktik: The Aswang Chronicles | GMA Films, Reality Entertainment | October 17 | ₱ 83,792,136 |
| 11. | 24/7 in Love | Star Cinema | November 21 | ₱ 75,057,886 |
| 12. | The Reunion | Star Cinema | August 15 | ₱ 68,112,967 |
| 13. | Moron 5 and the Crying Lady | Viva Films, MVP Pictures | April 7 | ₱ 64,642,363 |
| 14. | Born to Love You | Star Cinema | May 30 | ₱ 52,022,257 |
| 15. | Corazon: Ang Unang Aswang | Skylight Films, Reality Entertainment | March 14 | ₱ 51,389,780 |
| 16. | Every Breath U Take | Star Cinema | May 16 | ₱ 50,191,540 |
