2011 US Open – Wheelchair women's singles
# 2011 US Open – Wheelchair women's singles

Five-time defending champion Esther Vergeer defeated Aniek van Koot in the final, 6–2, 6–1 to win the women's singles wheelchair tennis title at the 2011 US Open.

## Seeds

* Esther Vergeer (champion)
* Jiske Griffioen (semifinals)

## Draw

### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Finals | Finals | Finals | Finals |
| - | - | - | - | - | - | - | - | - | - | - | - |
| 1 | Esther Vergeer | 6 | 6 | | | | | | | | |
| | Marjolein Buis | 1 | 0 | | | | | | | | |
| | Marjolein Buis | 1 | 0 | 1 | Esther Vergeer | 6 | 6 | | | | |
| | | | | | Annick Sevenans | 2 | 3 | | | | |
| | Daniela di Toro | 3 | 3 | | Annick Sevenans | 2 | 3 | | | | |
| | Annick Sevenans | 6 | 6 | | | | | | | | |
| | Annick Sevenans | 6 | 6 | | | | | 1 | Esther Vergeer | 6 | 6 |
| | | | | | | | | | Aniek van Koot | 2 | 1 |
| | Aniek van Koot | 7 | 6 | | | | | | | | | Aniek van Koot | 2 | 1 |
| | Sharon Walraven | 5 | 1 | | | | | | | | |
| | Sharon Walraven | 5 | 1 | | Aniek van Koot | 6 | 6 | | | | |
| | | | | 2 | Jiske Griffioen | 3 | 2 | | | | |
| WC | Emmy Kaiser | 2 | 2 | 2 | Jiske Griffioen | 3 | 2 | | | | |
| 2 | Jiske Griffioen | 6 | 6 | | | | | | | | |
