List of highways in Ponce, Puerto Rico
# List of highways in Ponce, Puerto Rico

This is a list of highways in Ponce, Puerto Rico. The list focuses on major, signed, roads in the municipality of Ponce, Puerto Rico. The list shows local roads, that is, those with both terminuses within the municipality ("intra-municipal" roads), as well as inter-municipal roads.

## List of highways

* PR-2 (Ponce Bypass) looking west
* PR-14 (a.k.a. Avenida Tito Castro) west of PR-10, looking west

| Route | Network | Axis | Southern or western terminus | Northern or eastern terminus | Type | Length, km (mi) | Notes |
| - | - | - | - | - | - | - | - |
| PR-1 | Primary | S to N | Ponce | San Juan | Inter-municipal | 133.7 (83.1) | via Cayey |
| PR-1P | Primary | W to E | Ponce | Tercero | Local | unknown | — |
| PR-2 | Primary | S to N | Ponce | San Juan | Inter-municipal | 230 (140) | via Mayagüez |
| PR-2R | Primary | S to N | Canas | Canas Urbano | Local | 1.6 (0.99) | — |
| PR-9 | Primary | S to N | Vayas | Canas | Local | 12 (7.5) | via Portugués; a.k.a. Expreso Román Baldorioty de Castro |
| PR-10 | Primary | S to N | Ponce | Arecibo | Inter-municipal | 68.26 (42.41) | via Adjuntas |
| PR-12 | Primary | S to N | Playa | Ponce | Local | 5.28 (3.28) | a.k.a. Expreso Santiago de los Caballeros |
| PR-14 | Primary | W to E | Ponce | Cayey | Inter-municipal | 73.1 (45.4) | — |
| PR-14P | Primary | W to E | Ponce | Machuelo Abajo | Local | unknown | — |
| PR-14R | Primary | W to E | Ponce | Machuelo Abajo | Local | unknown | — |
| PR-52 | Primary | S to N | Ponce | San Juan | Inter-municipal | 108 (67) | a.k.a. Expreso Luis A. Ferré |
| PR-123 | Secondary | S to N | Ponce | Arecibo | Inter-municipal | 60 (37) | via Adjuntas |
| PR-123P | Secondary | S to N | Primero | Ponce | Local | unknown | — |
| PR-132 | Secondary | W to E | Guayanilla | Ponce | Inter-municipal | 25.9 (16.1) | — |
| PR-133 | Secondary | W to E | Ponce | San Antón | Local | 2.0 (1.2) | a.k.a. Calle Comercio |
| PR-139 | Secondary | S to N | Ponce | Maragüez | Local | 24.8 (15.4) | — |
| PR-139R | Secondary | S to N | Machuelo Arriba | Maragüez | Local | 2.9 (1.8) | — |
| PR-143 | Secondary | W to E | Adjuntas | Barranquitas | Inter-municipal | 58.7 (36.5) | via Ponce |
| PR-163 | Secondary | W to E | Canas Urbano | San Antón | Local | 4.8 (3.0) | a.k.a. Avenida Las Américas |
| PR-500 | Tertiary | W to E | Canas | Magueyes | Local | 1.00 (0.62) | — |
| PR-501 | Tertiary | S to N | Ponce | Marueño | Local | 7.0 (4.3) | — |
| PR-502 | Tertiary | S to N | Ponce | Quebrada Limón | Local | 5.3 (3.3) | — |
| PR-503 | Tertiary | S to N | Cantera | Jayuya | Local | 21.8 (13.5) | — |
| PR-504 | Tertiary | S to N | Ponce | Portugués | Local | 6.7 (4.2) | — |
| PR-505 | Tertiary | S to N | Ponce | Machuelo Arriba | Local | 16.6 (10.3) | — |
| PR-506 | Tertiary | S to N | Cantera | Vayas | Local | 2.0 (1.2) | — |
| PR-507 | Tertiary | S to N | Capitanejo | Capitanejo | Local | unknown | As of around January 2023, this road seems to have lost its PR-507 designation as a new road is now signed with the PR-507 designation in Machuelo Arriba. This can be seen here, here, and here. This road now signed as PR-507 leads from PR-139 to the Luis A. "Wito" Morales Park. |
| PR-510 | Tertiary | S to N | Capitanejo | Juana Díaz | Inter-municipal | 10.3 (6.4) | — |
| PR-511 | Tertiary | S to N | Ponce | Anón | Local | 16.4 (10.2) | — |
| PR-515 | Tertiary | W to E | Guaraguao | Guaraguao | Local | 1.5 (0.93) | — |
| PR-516 | Tertiary | W to E | Guaraguao | Guaraguao | Local | 3.1 (1.9) | — |
| PR-520 | Tertiary | W to E | Peñuelas | Quebrada Limón | Inter-municipal | unknown | — |
| PR-549 | Tertiary | S to N | Canas | Canas | Local | 4.2 (2.6) | — |
| PR-577 | Tertiary | S to N | Anón | Anón | Local | 0.30 (0.19) | Cerro Maravilla; dead end road |
| PR-578 | Tertiary | W to E | Bucaná | Sabanetas | Local | 0.9 (0.56) | — |
| PR-581 | Tertiary | S to N | Capitanejo | Capitanejo | Local | unknown | — |
| PR-585 | Tertiary | S to N | Canas | Playa | Local | 3.8 (2.4) | — |
| PR-588 | Tertiary | S to N | Portugués | Portugués | Local | 1.7 (1.1) | — |
| PR-591 | Tertiary | W to E | El Tuque | El Tuque | Local | 3.1 (1.9) | — |
| PR-5139 | Tertiary | S to N | Cerrillos | Machuelo Arriba | Local | 2.8 (1.7) | — |
| PR-5506 | Tertiary | S to N | Vayas | Sabanetas | Local | 1.4 (0.87) | — |
| PR-5510 | Tertiary | S to N | Capitanejo | Juana Díaz | Inter-municipal | 1.4 (0.87) | — |
| PR-5549 | Tertiary | S to N | Canas Urbano | Canas Urbano | Local | unknown | — |
