Silene jenisseensis
# Silene jenisseensis

Silene jenisseensis, is a species of flowering plant in the family Caryophyllaceae, native to Siberia, Far East and Mongolia.

## Chemistry

Phytochemical analysis of Silene jenisseensis roots have found ecdysteroid 20-hydroxyecdysone, sterol α-spinasterol-3-O-glucoside, triterpenoids quillaic acid derivatives — jenisseensoside A, B, C and D. In herb of Silene jenisseensis flavone-C-glycosides were detected including vitexin, isovitexin, orientin, isoorientin, as well as ecdysteroids 2-desoxyecdysone, 2-desoxy-20-hydroxyecdysone, ponasterone A, dacryhainansterone, 20-hydroxyecdysone and integristerone A. Total content of ecdysteroids in Silene jenisseensis roots and herb collected in Buryatia Republic was 0.06% and 0.06—0.83%, respectively.

## Uses

Triterpenoids jenisseensoside A—D showed inhibitory effect in the cyclooxygenase inhibition assay, significant enhancement of the granulocyte phagocytosis, and cytotoxicity against human colon cancer cells (HP 29).

