PATENT MEDICINES.

mn CflNSTANTINE,S
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1adtchleSs for the thHS aud Fepef also dn e.

 fectHdl remedy for FsUas ot epoy denomination.

 FENIIE proprietor is induced ta believe from the

 N safe and certain cure that this medicine has ef fected, in all cases in winch il has been administer ed, that il has equal for the cure of these most distressing diseases, so prevalent m our southern and western countries. He has been prevailed np- on 10 offer it for sale to the public by the frequent solicitations of those who have been suddenly cured by the of it. after frequent trials of the most ap- proved medicines of the day had failed. These Pills noi only cure the Chills and Fever in all then most complicated forms, but they possess the adm- rable property of purifying Ihe blood, of removlng all morbid matter, of giving tone 10 the stomach, of increasing the appete of acting upon the liver and Inngs, thereby restoring the whole system to healthy action. They are, CarminaiVe, Ca medi- cine which tends 10 expel wind from the body,) Ex- pectorant, Tonic, Stimulant, Diaphoretic, Anodyne and Anti-Spasmatic. All who will gives these pills a fair trial will find this to be the fact. There is no mineral in these pills, or any thing that is poisonous in it's nature. They pefectly harmless, and may be taken with entire safety at all times, and ln all situations by both They are offered to the public for the benefit of mankind, carefully compos- ed of such vegetable ingredients as are calculated 10 assist nature in overcoming disease; and from the numerous testimonials the proprietor has received, | from those who have beer ured at once by the use ofthese pills, he IS of the .uon that il will be kuowledged matchlcss sahdtive for clls and fever, and valuable medicine in the treatment of levers of every description.

 l DIREcTIoEs.-ln continued levers, these pills should be taken at any tune, that the regular hours observed; hut in of the chls and fe- vers that return periodically, they should al any | rate, as we'll as at other times, be used in the sweating stage. In cases of stubborn character, take two pills every hour for three hours previous | to the tune of the chill coming These pills safe and salutary, perfectly in harmony with nature, and the active stimuant to support and reani- mate her feeble and exhausted powers. This medi- cine is powerful in it's effect in removing diseases, | yet there will not be the least danger of a small child talk ing double dose, and perfectly safe to the constitution, In all where the chiIls have been 1 of long standing, and impaired the constitution, the patient should take dose of the anti-biious before commencing with the Ague pills, repeating the Anti bilious pulls every three or four days, and continue take the Agne pills for several days after the chs

 heve been broken. Disease if suffered run its course with but occasional checking, until the system is entirely exhausted by the repeated attacks, will m all probability, all the dreadful complaints of

 Consumption, Drq,sy, Liver Complaint, Dyspepsia, and many others, which too often bafie the skill of all medical sclence. If any should feel like be- ing sick, or in travelling through sicky country, a

 few of these pills w before disease becomes seated | m the system, give immediate relief. Remember the

 old p,overb 'an ounce of preventive Is better than | pound cure.'

 GEEERAL OBSERVATIONS This medicine pos-

 sesses ths great ard decided advantage where it is

 kept by families IL places the physician and remedy at

 home. You have not to wander al the hour oi midnight

 in search ofa physician with the lmpressl n on your

 mind that some of your family may be dead before

 you return home. You may, by taking dose o the

 Ant-bous pills, nip the fever in it's infancy.

 | MOBILE, Ala. April I3, lS43.

 DR. F. L. CoEsTAErIsEI Sir.-For tue benefit

 of the community at large, and as an act of justice to

 yourself take tis method gratefully to acknow,

 ledge the surprising and almost miraculous benefit

 have derived from the use of your Vegetable Ague

 Pills. About eleyen months since, was attacked with chiIls and fever. immediately placed mysel

 under the direction of skilul physician, who treat

 al my case for several weeks without any benefit tt

 me. then resorted to another, with no better sue

 cess. Hearing of Chapman's Celebrated Fever ant

 Ague Pills, was induced, through the persuasion 0 my friends tO give them a tr,al, and used seVera

 boxes wi,hou deriving any benef, from them.

 then resoried 10 Sappngtoh's Pills, which used fol z several weeks, but derived no benefit from ihem- I despared of finding relief from any source, an' concluded my situation altogether hopeless. ] ha' now become much emaciated-my strength almos

 wholly exhausted, my appetite gone and my who'll

 frame racked with pain Just at this stage of m.

 disease, in addition the ills suffered, distress ing Dysentery made it's appearance, which complete ly prosrated me. For the last four days, l threv up every thing that ate and drank. ] was unable

 to rest at night, and scarce able to walk across m room, and not without reel,ng like one intoxicated heard you were in this city, and immediately mad application to you and now, after having used twi boxes of your Ague Pills, find myself restored to degree of health had despaired of ever again en toying. My chills have left me, the dysentery ha disappeared under the magic effects, my appetite lestored, and returning strength and animation seen , to thrill my every nerve. Toy owe everhstin gratitude, and shall ever while live hail your ines timiabe Pills as my deliverer from wasting dseas and certain death. THOS. FLEMMlNG. , We, the undersigned, personally acquainted with Mir. Flemming, and fully aoroborae the state ment above made. WILLIAM BIRD, ABRAM GREER.

 Certificate qf Rep Leroy Massengals Methodist Preach CT, Norubee County, Miss May 9th, lS43.

 This is to certify that was afflicted with ihe Sy nocbal Fever, fever of highly inAammatory charac

 ter, which had fallen upon my bowels and produced

 a soreness and swelling. that could not bear thu

 least pressure without excruciatng pain. took oi and pills with small portion of caomel for severa , days and found no relief. but grew daily;

 then sent for Dr. Constantine, believing hun to be tn

 safest practitioner in the country, and he gave me hi Ague Pills, with some other medicine, which gave m immediate relief. My little has been afflicted with the sick headache all his life. took only sma

 box of these pills and Is measurably relieved, if no entirely. therefore feel confident in recommending these pills to the public. LEROY MAssENGALE. To be had of I. c. DUBOSE, & CO.,, DR. CONSERVATIVES

 Anti-BiliOus, Vegetable, PurgatiVe and Reno