PATENT MEDICINES.

DIR. CONSTANTlNE,S
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DIR. CONSTANTlNE'S

 VEGETA BILE 4 UE PILLS.

 matchlsSs care for the Chs aud Fever, also an ef-

 f,efuai remedyfo Ferers of eVsry denomination. HlHE proprietor IS induced to believe from the safe and certain cure that this medicine has ec feced in all cases in winch if has been administers ed, that il has no equal for the cure of these most distressing diseases, prevalent in southern and western countries. He has been prevailed up- on offer t for sale lo the public by the frequent solicitations of those who have been suddenly cured by the use Of t, aler frequent trials of the most ap- proved medicines of the day had failed These Pills moi only the Chills and Fever in all theii most complicated forms, but they possess the admi- rabe property of purifying lhe blood, of removing all morbid matter, ol giving tone to the stomach, of increasing the appetite, of acting upon the liver and nngs, thereby restoring the whole system to a healthy action They are, Carminative, Ca medi- cine which tends to expe wind from the body) Ex- pectorant, Tonic, Stnulsnt. Diaphoretic, Anodyne and Anti-Spasmatic. All who will gves these pills

 fair trial, will find this 10 be the fact. There is no mineral in these pills any thing that poisonous in it's nature. They peiectly fmrmless and may be taken with entire safety at all lmes and m all situations by both sexes. They are offered to the public for the benefit of mankind, carefully compos- ed of such vegetable ingredients calculated to assist nature in overcoming disease; and from the numerous testimonials the proprietor has received, from those who have been cured al by the use of these pills, he oi the orlnon that it will be &C., kuowedged matchess sanative for chils and fever, and valuable medicine in the treatment of levers of every desci ipllun.

 DIREcTioSs.-ln continued levers, these pills should be taken at any tune, that the regular hours are observed but in ofthe chills and le- vers that return periodically, they should at any rate, as well $ at other times, be used in the sweating stage. In cases of stubborn character, take pills every hour for three hours previous to the tune of the chill coming on These pills are

 

 and the most active stimuant to support and reani mate her feeble and exhausted powers. This medi- cine is powerful in its effect in removing diseases yet there will not be the least danger of a small child taking double dose, and perfectly safe to the constitution In all cases where the chs have been of long standing, and impaired the constitution, the patient should take d dose of the anti bilious benre commencing with the Ague pills repeating the Anti bilious pills every three or four days, and continue to take the Agne pills for several days afer the chills he e been broken. Disease if suffered run its course with but occas sionil check ing until ihe system is entirely exhausted by the repeated attacks, will in all probability, cause all the dreadful complaints of Consumption, Dropsy, Liver Complaint, Dyspepsia. and many others, which too often battle the skill oi all medical science. Ii any should feel like be. ing sick, in travelling through sicky country few of these pills wilt before disease becnmes seated m the system, give immediate relief. Remember ,lle old p,overb "an ounce of preventive is better than Il pound cure."

 GENERAL OBSERVATIONS This medicine pos thIs great and decided advantage where il is kept by families. ltp places fhe physician and remedy home. ou have not to wander the hour of midngh in search oft physician, with the mpressi on your mind that some of yonr family may he dead before you return home. You may, by taking dose of the Anli-bous pills, nip the fever in its infancy.

 MOBILE, Ala. April Is, lS43. DR. F. l.. CoEsTAHTINE: Sr.-For ihe benefit of the community at large and as an act of ustce to yourself, take this method gratefully 10 acknow- ledge the surprising and almost miraculous benefit have derived from the use of your Vegetable Ague Pills. About eleven months si1ce, was attacked with chills and fever. immediately placed myself under the direction of sk ul physician, who reat sd my for several weeks without any benefit to me. then resored in another, with no better suc- cess. Hearing oi ChapmaD's Celebrated Fever and Ague Pills, induced, through the persuasion o my friends to giye them tral, and used several boxes without deriving any benefit from them then resored Sappngton's Pills, which used for several weeks, but derived no benefit from ,hem.-- despaired of finding relief from any source, and concluded my situation altogether hopeless. l had now become much emaciated-y,ny strength almost | wholly exhausted, my appetite gone and my whole frame racked with pain. Just at this stage of my disease, in addition 10 the ills suffered, distress ing Dysentery made it's appearance, winch complete ly prostrated me. For the last four dsys, threw up every thing that ate and drank. was unable rest at night, and scarce able to walk across my room, and not without reeling like one intoxicated. l heard yon in this city, and immediately made application to you, and now, after having used two boxes of your Ague Pills find myself restored to degree of health I had despaired of ever again en- toying. My chills have left me, tine dysentery has disappeared under the magic effects, my appetite is Iestored, and returning strength and animation seem to thrill my every To you owe everlasting gratitude, and shall ever while live hail your ines timabIe Pills as my deliverer from wasting disease and certain death. THOS. FLEMMlNG.

 We, the undersigned, personally acquainted with Mir. Flemmng, and fully coroborate the state ment above made. WILLIAM BIRD,

 ABRAM GREER. Certificate a Req Leroy Massengals, Methodist Preach

 CT, Norubee County, Miss. May 9th, lSi3.

 This is to certify that was afflicted with ihe Sy- nochal Fever, fever of highly infammatory charac- ter, which had fallen upon my bowels and produced a and swelling. that could not bear the least pressure without excruciating pain. took oil and pills with small portion of calomel for several days and found no relief, but grew daily; then sent for Dr. Constantine believing hun to be the safest practitioner in the country and he gave me his Ague Pills, with some other medicine, winch gave immediate relief. My little has been afflicted with the sick headache all his life, took only small box of these pulls and is measuraby relieved, if not entirely. therefore feel confident in recommending these pills to the public. LEROY MAssENeALE.

 To be had of I.C. DUBOSE, & CO.,,

 24 39 Water street. Mobile,