PATENT MEDICINES.

nR CONSTANTINE,S
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safe and certain that thIs medicine has ei- iected, in all cases in winch il has been administer ed, lhat il has no equal for the Of these distressing diseases so prevalent in our southern and western countries. He has been prevailed up- offer il for sale to Ihe public by the frequent solicitations of those who have been suddenly cured by the of it, after frequent tras of ihe most ap- proved medicines of the day had failed. These Pills only cure the Chills and Fever in all the most complicated forms, but they possess the adm- rabe property of purifying the blood, of renoving all morbid matter, of giving tone to the stomach, of increasing the appetite. of acting upon The liver and lnngs. thereby restoring the whole system to q healthy action. They are, CarninailYe, Ca medi- cine which tends 10 expel wind from the body,) Ex- pectorant, Tonic, Stilnusnt, Diaphoretlc, Anodyne and Ant-Spasmatic. All who will given these pills a fair tral will find this to be the fact. There is no mineral in these pills, any thing that IS poisonous in it's nature. They are peecily harmless, and may be taken with entire safety at all times, and m all situations by both sexes. They are offered to the public for the benefit of mankind, carefully compos- ed of such vegetable ingredients as are calculated 10 assist nature n overcoming disease; and from the numerous testimonials the proprietor has received, | from those who have beer ured at once by the use ofthese piIls he IS of the non that il will be kuowledged nlalchless saLAiiye for cis and lever, and valuable medicine in the treatment of levers of every description.

 l DIREcrIoNs.-ln continued levers, these pills should be taken at any tune. $" ibat the regular | vers that return periodically, they should al any rate, as well as at other times, be used in the sweating stage. In of d stubborn character, take two pills every hour for three hours previous to the tune of the chill coming These pills are safe and sautary perfectly in harmony with nature, and the active siinulant to support and reani- mate her feeble and exhausted powers. This medi- cine is powerful in it's effect m removing diseases, l yet there will not be the least danger of a small child tsk ng double doso, and perfectly safe to the 1 hnr. sl,. I,a. of long standing. and impaired the constitution, the patent should lake dose of he antibiious before commencing with inc Ague pills, repeating the Anti bilious pills every three or four days, and continue to take the Agne pills for several days after the chis | heve been broken. Disease if suffered 10 run its course with but occasional checking, until the syslen, is entirely exhausted by the repeated attacks, will in all probability, cause all the dreadful complaints of Consumption. Drtpsy, Liver Complaint, Dyspepsia, and many others, which often bale the skill of all medical science. If, any one should feel like be. | ing sick, or in travelling through sickly country, a few of these pills will before disease becomes seated | m the system, give immediate reef Remember the old pioverb Gan ounce of preventive is better than | pound Cure"

 | GENERAL OBSERVATIONS This medicine pos sesses ths great and decided advantage where il is kept by families. Itplaces the physician and remedy al home. ou have notto wander at the hour of midnight in search ofa physician, with the Impressi n on you' | mind that some of your family may be dead before you return home. You may, by taking dose of ht Anti-bious pills, pip the fever in its infancy.

 MOBILE, Ala. April I3, lS43. | DR. F. l.. CONSTANTINE: Sir.-For the beneh of the community large, and act of jistce t yourself, take this method gratefully to acknow ledge the surprising and almost miraculous benefit have derived from he use of your Vegetable Agu | Pills. About eleven months since, was atlacke, with chiIIs and fever. I immediately placed mysel under tine direction of skul physician, who treat sd my case for several weeks without any benefit Il me. 1 then resorled to another, with no better sue cess. Hearing of Chapman's Celebrated Fever an Ague Pills, was induced, through the persuasion 0 my friends to give them iral and used severa boxes without deriving any benefit from them

 then resorled 10 Sappington's Pills, which used o several weeks, hut derived no benefit from ihem.- | despaired of finding relief from any source, an concluded my situation altogether hopeless. l ha now become much emaciated-my strength alnos wholly exhausted, my appetite gone and my whol frame racked with pain Just at this stage of m disease, in addition to the ills suffered, distress ing Dysentery made it's appearance, winch complete ly prostrated me. For the last four days, thre, up every thing that ate and drank. ] was unabl to rest at night, and scarce able to walk in room, and not without reelmg like one ntox xlcated heard you in this city, and immediately mad application to you, and now, after having used tw boxes of your Ague Pills, find myself restored to degree of health had despared of ever again en toying. My chills have left me, the dysentery ha disappeared under the magic effects, my appetite Iestored, and returning strength and animation seer to thrill my every nerve. To you owe everlastin grat,tude and shall while live hail your ines timable Pills as my deliverer from wasting diseas and certain death. THOS. FLEMING.

 We, the undersigned, are personally acquante with Mir. Flemming, and fully coroborale the state ment above made. WILLIAM BIRD,

 ABRAM GREER.

 Certificate a Rev Leroy Masseg gale Methodist Preach

 CT, Norubes County, Miss May 9th, 1843.

 This is to certify that was afflicted with Ihe Sy nocial Fever, fever ofa highly inAammatory charac ter, which had fallen upon my bowels and produces a soreness and swelling. that could not bear tn least pressure without excruciating pain. btook oi and pills with small portion of caomel for days and found no relief. but grew worse day

 then sent for Dr. Constantine, believing hlm to be h safest practitioner in the country, and he gave me hi Ague Pills, with some other medicine, winch gave m immediate relief. My little has been aflcte with the sick headache all his life. took only sma box of these pills and is measurably relieved, if no entirely. therefore feel confident in recommendin these pills to the public. LEROY MAssENeALE.

 To be had of l. c. DUBOSE, & CO.,, | m nNlsyfV AIfit ISsS