PATENT MEDICINES.

DR. CONSTANTlNE'S
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mdfcaesS cms J0r the ChHS and Feper. also ef- teciadi ren,edyJor Fslers of epay denonlinahon. fEtHE proprieto, Is indured L, believe from the safe and certain that this medicine has ef- iected m ali cases in winch it has been adm ed, at II has equal for the of these most distressing diseases, so prevalent in our southern and western countries. He has been prevailed up- on 10 offer II for sale to Ihe public by the frequent solicitations of those who have been suddenly cured by the use oi it. after frequent trials of the most ap- proved medicines of the day had failed. Thete Pills mol ouly the Chills and Fever in all lle

 nost complicated forms, but they possess the adni- rabe property of purifying Ihe boSd of removing all morbid natter of giving to the stomach. of increasing ihe appetite of acting upon the liver and lnngs, thereby restoring the whole system to a healthy action. They are, Carminatve, Ca medi- cine which tends to expel wind from the body,) Ex- peetorant, Tonic, Stimulant, Diaphoretic, Anodyne and Anti pasniaiic, Al who will giyeE these pills fair trial, will find this to he the fact. There is no mineral in these pills, or any thing that is poisonous in it's nature They perfectly harmless, and may be taken with entire safety ni all times and m all situations by both sexes. They offered to the public for the benefit of lind, carefully compos- ed such vegetable ingredients calculated to assist nature in overcoming disease; and from the numerous testimonials the proprietor has received, from those who have heen cured a by the use Ufthcsr pills, he of the ornion that it will be ac- knowleged T malchless sauatye for chills and fever, and valuable medicine in the treatment of levers of every desct iptInn.

 | DIRECTIoNs.-m continued levers, these pills should be taken at any iimc. so that tha regular hours are observed; hut m eases ul the chis and e vers tlnat return periodically, they should any rate, as well as at other times, he used in the sweating stage. In cases of a stubborn character, take two pills every hour for three hours previous to lhe tune of the chill coming on These pills are safe and salulary, perfectly m harmony with nature, and the most active siimulant 10 support and reani mate her feeble and exha isled powers. This medi- cine is powerful in its effect m removing dsea 'es l yet there will not be the least danger of a small child akIng double dose and perfectly safe n the constitution. In all cases where the c.is have hcen of long standing, and impaired the constitution, the patient should take dose of the anti.bi0us before commencing with he Ague pills, repeating fine Anti bilious pills every three or four days and continue to take the Ague pills for several days after the chs heve been broken. Disease lf suffered 10 run its course with bu, occasional checking until the system is entirely exhausiedby the repeated attacks, ill Tn all probability, cause all the dreadful complaints of Consumption, Drupsy, yer-Compant, Dyspepsia. | and many others, winch too often bafhe the skill oi all medical science. If any should feel like be- ing sick, or in travelling through sickly country, few of these pills will before disease becomes seated m ihe system, give immediate rcliei. Remember the old poyerb ''an ounce of preventive is better than l a pound Care ''

 1 GENERAL OBSERVATIONS This medicine pos. sesses this great and decided vantage where il is kept by families. lt places he physician and remedy hpme. You have not to wander a the hour of idnghi in search oi a hysician, with the snsress your | mind that of your family ma, he dead before you return home. You may, by taking dose of the Ant-bIious pills, nip he fever in its infancy

 | MOBILE, Ala. April l3, 1913. | DR. r. L. CoHsTASTINE: Sir,-Fur ihe h-ne6t of the community at large, and act of justice to yourself take this method gratefully 10 acknow- ledge the surprising and almost miraculous benefit 1 | have derived from the of your Vegetable Agu' Pills. About eleven months since, was attacked oh, I nt ,sali under the direction of skul physician, who treat. sd my case for several weeks without any benefit o | me. then resorted 10 another, with m better sue. cess. Hearing of Chapmans Celebrated Fever and Ague Pills, was induced, through ihe per, r,uasinn "i | my friends 10 gIve them d tra, and used several boxes without deriving any benefit from them ] then resored To Sappington's Pills which used for | several weeks, bat derived no benefit from them - despaired of finding relief from any source, and | concluded my situation altogether hopeless. l had | now become much euaciaed-iDy strength almost wholly exhausted. my appetite gone and my whole | frame racked with pain. Just at this stage oi my dsease in addition 10 the ills suffered, distress ing Dysentery made it's appearance, winch complete. iy prostrated me. For the last four dsys, l threw | up every thing that ate and drank. ] was unable to rest at night, and scarce able to walk my | room, and not withou, reeng like one intoxicated heard you were in this city, and immediately made application to you, and now, after having used two boxes of your Ague Pills, find myself restored 10 a degree or neaitn nau uespalfeu Oi ever again en- toying. My chills have left me, the dysentery has disappeared under the magic effects, my appetite is

 esored, and returning strength and animation seem | to thrill my every nerve. To you l owe everlasting graiiludc and shall while live hail your ines timtble Pills my deliverer from wasting disease and certain death. THOS. FLEMING.

 We, the undersigned, personally acquainted with Mr. FIemming, and fully c,rpboraie the state ment above made. WILLIAM BIRD,

 ABRAM GREER.

 Certificate af Reu Leroy assengaie Methodist Preach

 CT, Norubee County, Miss. May 9th, l843.

 This is to certify that was afflicted with Ihe Sy- nochal Fever, fever ofa highly infammatory charac- ter, which had fallen upon my bowels and produced d soreness and swelling, that could not bear the least pressure without excruciating pain. took oil and pills with small portion of caomel for several days and found no relief but grew worse day 1 then for Dr.. Constantine believing hun to be the safest practitioner in the country and he gave his | Aguc Pills, with some other medicine, which gave me immediate relief. My little has been afflicted with the sick headache all his life. took only small box of hese pulls and is measuraby relieved, if not entirely. therefore feel confident in recommending these pills to the public. LEROY MAssEEGALE.

 To be had of I.C. DUBOSE, x CO.,, | 24 39 Water street. Mobile. | NJE AND VAI(1ARI E MEDICINE for ibs