PATENT MEDICINES.

ma. cONsTANTINE,s
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 matchiess cure for the ChiHs aud Fepe, also sf 1 tecfudi remedyfor Feues of evvy denomination. VEfHE proprietor Is induced to believe from ihe

 A safe and certain cure that this medicine has ef- feeted, m all cases in winch il has been administer ed, that if has equal for the of these most distressing discusses, prevalent in southern and western countries He has been prevailed up- on o offer it for sale the public by the frequent solicitations of those who have been suddenly cured by the use of it, after frequent trials of the ap prayed medicines of the day had failed. These Pills moi only cure the Chils and Fever in all heii most complicated forms, but they possess the adni- rable property of purifying the blood, of remnving all morbid matter, of giving tone to the stomach, of increasing the appetite. of acting upon the liver and lungs, thereby :oring the whole system to q healthy action. They are, Carminative, Ca medi- cine which tends to expeI wind from the bodyO Ex- pectorant, Tonic Stimulant, Diaphoretic, Anodyne and Anti-S Spasmalc. All who will giyeG these pills fair trial, will find this to be the fact. There is no mineral in these pills, any thing that is poisonous in it's nature. They are pelectly harmless and may be taken with entire safety at all times, and Tn all

 situations by both sexes. They are offered to the public for the benefit of mankind, carefully compos- ed of such vegetable ingredients are calculated assIst nature in overcoming disease; and from the numerous testimonials the proprietor has received from those who have been cured at by the use of these pills, he IS o the orinon that it will be knowledged malchless sanatve for chills and lever and valuable medicine in the treatment of levers of every descr ipion.

 DIRECTIoNs.-ln continued levers, these pills should be taken al any tune. that the regular hours observed; but in cases of the chs and ie- vers that return periodically, they should at any rate, as well as at other times, be used in the sweating stage. In cases ofa stubborn character, take two pills every hour for three hours previous to the tune of the chill comng These pills are safe and salulary perfectly in harmony with nature and the most active simulant to support and reani mate her feeble and exhausted powers. This medi- cine Is powerful in it's effect in removing diseases, yet there will not be ihe least danger of small

 child talk ing double dose, and perfectly safe to the constituiIon In all cases where the chls have been of long standing, and impaired the constitution, the patent should take dose of the ani-bilious before commencing with he Ague pills repeating the Anti bilious pills every three four days, and continue to take the Agne pills for several days after the chls heve been broken. Disease if suffered run Its course with but occasional checking, until the system

 is entirely exhausted by the repeated attacks, will in all probability, cause tl,e dreadful complaints of Consumption. Dropsy, Liver-Compaint, Dyspepsia. and many others, which too often baflle the skill of all medical science. If any should feel like be-

 ing sick, in travelling through scklv country, a few of these pills will, before disease becomes seated m the system, give immediate relief. Remember the old overb ''an ounce of preventive Is better than | n pound Cure"

 GENERAL COMBINATIONS This medicine DOS. sesses ths great and decided advantage where it is kept by families. places inc physician and remedy at home. You have not to wander at the hour o midnight

 in search of physician, with the impress on your mind that some of your family may be dead before you return home. You may, by taking dose oi the Ambitious pills, nip the fever in its infancy.

 MOBILE, Ala. April l3, lS43. DR. F. L. CoNsTANTINE: Sir.-For the benefit of the community at large, and act of justce to yourself, take this method gratefully 10 acknow- lode haaa have derived from the use of your Vegetable Ague | Pills. About eleven months siace, was attacked | with chlls and fever. immediately placed myself under the direction of skiu physician, who ireat- cd my case for several weeks without any benefit 10 me. then resoried to another, with better suc- cess Hearing of Chapman's Celebrated Fever and Ague Pills, induced. through the persuasion of | my friends giye them irml, and used several | boxes without deriving any benefit from them. l then resored Sappington's Pills, which used for several weeks, bu, derived no benefit from ihem.- I despaired of finding relief from any source, and concluded my situation altogether hopeless. had now become much emacated-ny strength almost wholly exhausted, my appetite gone and my whole | frame racked with pain. Just at this stage of my disease, in addition the ills sufered distress ing Dysentery made its appearance, winch complete- ly prostrated me. For the last four days, threw | up every thing that ate and drank. l was unable to rest at night, and scarce able walk across my room, and not without reeling like intoxicated. heard you were in this city, and immediately made application to you, and now, after having used two boxes of your Ague Pills, find myself restored to d degree of health had despaired of ever again en- toying. My chills have left me, the dysenlery has disappeared under the magic effects, my appetite is Iestored, and returning strength and animation | to thrill my every nerve. To you owe everlasting gratitude, and shall while live hail your ines- tmable Pills az my deyerer from wasting disease | and certain death. THOS. FLEMING. We, the undersigned, are personally acquainted with MT. Flemming, and fully ooroborate the slate- | ment above made. WILLIAM BIRD, ABRAM GREER.

 Certificate af Rey. Leroy Massengals, Methodist Preach CT, Norubee County, Miss. May 9th, 1s43.

 This is to certify that was afflicted with ihe Sy- nochal Fever, fever of highly infammatory charac- ter, which had fallen upon my bowels and produced a soreness and swelling. that could not bear the least pressure without excruciating pain. took oil and pills with small portion of calome for several days and found no relief. but grew worse daily; I then for Dr. Constantne believing hIm to be the safest practitioner in the country, and he gave his Ague Pills, with some other medicine, winch gave immediate relief. My lilte son has been afflicted with the sick headache all his life. took only small box of these pills and is measuraby relieved if not entirely. therefore feel confident in recommending these pills to the public. LEROY MAssENeALE. To be had of 1. c. DUBOSE, & CO.,, 24 39 Water street. Mobile. NEW AND VALUABLE MEDICINE for Me