- PATENT MEDICINES.

DR. CONSTANTINE,s
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 Jscfuai rsmedyto Fetsrs of es,ry denomination. TsHE proprietm is induced tn believe irciu the ' safe and certain that this medicine has CT fected, in all cases in winch it has been administer ed, that il has equal for The of these most distressing diseases, so prevalent in nur southern and western countries. He has hren prevailed up- on 10 offer ii for sale o te public hy he frequent solicitations nf those whl have been suddenly cured by the of aler frequent trials of the most ap- proved medicines of the day had iailcd. These Pills only cure the Chlls and Fever in all thei, mosi complicated forms, h,a they possess the admi- rabe property of purifying the blood, of reInovng all morbid matter, o giving tDne tO the stomach, ot increasing the appetite. of acting upon the liver and lnngs, thereby restoring the whole system to healthy action. They are, CarIninaiiye, Ca medi- cine which tends lo expe wind from the body,) Ex- pecioranI, Tonic. Stmulant, Diaphoreiic, Anodyne and Anti-S Spasmatc. All who will gyea these pills fair trial, will find this to be the fact. There IS no mineral in these pills, any thing that is poisonous in it's nature. They are pefectly harmless, and may be taken with entire safety at all times, and m all situations by both sexes. They are offered to the public for the benefit of mankind carefully comPos- ed of such vegetable ingredients calculated to assist nature in overcoming disease; and from the numerous testimonials the proprietor has receised, from those who have been cured at once by the use of these pills he of the ornion that il will be ac- know letged matchess sanative for clis and lever, and valuable medicine in the treatment of levers of | esery desci ipion.

 DIREcTioSs.-ln continued levers, these pills should be taken at any tune. that the regular hours oiseryed; hut in of the chiis and ie- yer4 that return periodically, they should at any | rate, as well as at other times, he used in the sweating stage. lm cases of a stubborn character, take twu pills every hour for three hours previous to the tune uf the chill coming These pills are safe and sulutary, perfectly in harmony with nature. and the most active s,nulant support and reani- mate her feeble and exla isted powers. This medi- cine Is powrrul in it's effeci in removing disease vet there W itl not be the least danger of small child iak ing double dose, and perfectly safe the cons itu In all cases where the clls have been of long standing. and impaired the constitution, the patent should take dose of the anti.bous before commencing with the Agme pills, repeating the Anti bilious pills every three four days, and continue take the Ague pills for several days afier the chils heye been broken. Disease if suffered run It's course with but occasional checking, until the system is entirely exhausted by the repeated attacks, will in all probability, all the dreadful complaints of Consumption, Dropsy, Liver-C Complaint, Dyspepsia. and many others which too often haile the six i'll of all medical scieuce. If any should feel like be- ing sick, in travelling through sckly country, few of these pills will, before disease becomes seated m the system, give immediate relief Remember the old p,oyerb San ounce of preventive is better than | pound cure.'

 | CEREBRAL OBSERVATIONS This medicine pos sesses ths great and decided advantage where it is kept by families IL places ihe physician and remedy al home You have not to wander the hour of midnight m search of a physician. with the mpressi your mind tl,i, of your family ms, be dead before you return home. You may, by taking dose of the Anl-bous pills, nip the fever in its infancy.

 MOBILE, Ala. April I3, lS43. DR. F. l.. CoEsTAHTINE: Sir.--For the benefit of the community al large, and act of istice tC yourself, take this methnd gratefully to acknow. ledge the surprising and almost miraculous benefit have derived from the use of your Vegetable Agus Pills. Aboul eleven months siace, was attacked with chills aud fever. l immediately placed myself under the direction of sk ilful physician, who treat s my cas- for several weeks without any benefit tt me theu resorled 10 another, with no better sue cess. Hearing of Chapnan's Celebrated Fever and Ague Pills, was induced. through the persuasion my friends give them trial, and used severa boxes without deriving any benefit from the,a then resorIed to Sappngton's Pills which used fo several weeks, hat derived no benefit from ,hem.- I despaired of finding relief from any source, ant concluded my situation altogether hopeless. l had now become much emaciated-my strength almost wholly exhausted, my appetite gone and my whole frame racked with pain. Just at this stage of my disease, in addition the ills suffered, distress ing Dysentery made it's appearance, winch complete ly pros,rated me. For the last four d"ys, l threw up every thing that ate and drank. unable to rest at night and scarce able to walk m, room, and without reelIng like ntox icated heard you were in this city, and immediately made application to you, and now, after having used tw6 boxes of your Ague Pills, find myself restored 10 degree of health had despaired of ever again en joying My chls have left me, ihe dysenIery ha, disappeared under the magic effects, my appetite i, Iestored, and returning strength and animal ion seen to thrill my every nerve. To you owe everlasting gratitude, and shali ever while live hail your ines timable Pills as my deliverer from wasting disease and certain death. THOS. FLEMING.

 We, the undersigned, personally acquainted with Mr. Flemming, and fully c,roborate the state ment above made. WILLIAM BIRD,

 ABRAM GREER.

 Certificate af Rsu. Leroy Masssngale Methodist Preach

 CT, Norubes County, Miss. May 9th, 1S43.

 This is to certify that afflicted with he Sy. nochal Fever, fever ofa highly inAammatory clarac ter, which had fallen upon my bowels and produced a and swelling. that could not bear the least pressure without excruc ciatng pain took oi and pills with small portion of caIomel for severa days and found no relief. but grew worse daily then for Dr. Constantine, believing hun to be the safest practitioner in the country, and he gave me his Aguc Pills, with other medicine winch gave me immediate relief. My little has been afflicted with the sick headache all his life. took only a sma box o these pills and is measuraby relieved, if mol entirely. therefore feel confident in recommending these pills to be public. LEROY MAssEEoALE.

 To be had of l. c. DUBOSE, & CO.,,

 24 39 Water street. Mobile