.. PATENT MEDICINES.

DR. CONSTANTINE,S
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naatchless cure for the ChIy and FeUeE, also e

 feetaal rsmedyfo7 Fevsrs cf euery denomination.

 YNHE proprietor is induced to believe from the

 l safe and certain cure thai this medicine has ef- fected, in all in winch t has been admnster- ed, that il has equal for the cure of these most distressing diseases, so prevalent in our southern and western countries. He has been prevailed up- on 10 offer il for sale to the public by the frequent solicitations of those who have been suddenly cured by the Of it, after frequent trials Oi the most ap proved medicines of the day had failed. These Pills not only cure the Chills and Fever in all theii most complicated forns, but they possess the adm rable property of purifying Ihe blood, of removing all morbid matter, of giving tone to the stomach, of increasing the appetite, 0l acting upon the liver and lnngs, thereby restoring the whole system to healthy action. They are, Carmlnalve, Ca medi- cine which tends 10 expel wind from the body,) Ex- pectorant, Tonic. SuinuIant, Diaphoretic, Anodyne and An-Spasmalic All who will given these pills a fair trial, will find this to be the fact. There is no mineral in these pills or any thing that is poisonous in it's nature. They are pelecty harmless and may he taken with entire safety at all times, and m all situations by both They are offered to the public for the benefit of mankind. carefully compos cd Of such vegetable ingredients as are calculated to assist nature in overcoming disease; and from the numerous testimonials the proprietor has received, from those who have been cured at once by ilie use ol these pills, he of the ornion that will be ac- knowledged matchess sanallve for chiiis and lever, and valuable medicine in the treatment of levers of every description.

 DiREcTIoHs.-In cont inned levers, these pills should be taken at any tune, SD that iht regular hours observed; hut in of the cbs and fe- serS that return periodically, they should at any | rate, as well as at other times, be used in the | sweating stage. In cases ofa stubborn character, take two pills every hour for three hours previous 10 the tune of the chill coming These pills safe and sautary, perfectly in harmony with nature, and the most active simulant to support and reani- mate her feeble md exhaised powers. This medi- is ,.l iga yet there will not be the least danger of small child talk ing double dose, and perfectly safe to the constitution. In all cases where the chills have been of long siandng and impaired the constitution, the paieni should take dose of the anli-bilious before commencing with ihe Ague pills, repeating the Anti bilious pills every three four days, and continue take the Ague pills for several days after the chills heye been broken. Disease if suffered 10 run its with but occasional checking until the system | is entirely exhausted by the repeated attacks, will in all probability, cause all the dreadful complaints of Consumption, Dropsy, Liver-Complaint, Dyspepsia. and many others, which too often baille the skill of all medical scence. If any should feel like be- ing sick. or in travelling through sicklv country, few of these pills will, heore disease becomes seated

 m the system, give immediate relief. Remember the old pIoyerb san ounce of preventive is better than | pound cure."

 | GENERAL OBSERVATIONS This medicine pos sesaes thus great and decided advantage where il is kept by families IL places the physician and remedy al

  in search of a physician, with the impress your mind that some of your family may be dead before you return home. You may, by taking dose of the Anti-biious pills, nip the fever in it's infancy.

 MOBILE, Ala April B, lS43. | DR.FL CoKsTAKTiNE: Sir.--For the benefit of the community large and of justice to yourself, take this method gratefully to acknow- ledge The surprising and almost miraculous benefit l have derived from the use of your Vegetable Ague l Pills. About eleven months since, was attacked I under the direction of kul physician, who treat ,i my case for several weeks without any benefit 10 me. then resoried to another, with no better suc- | cess. Hearing of Chapman's Celebrated Fever and 1 Ague Pills, induced, through the persuasion o l my friends to give them lral, and used several boxes wi'hou, deriving any benefit from theia then resored 10 Sappngton's Pills which used for l several weeks, but derived no benefit from lhem.- despaired of finding relief from any source, and | concluded my situation altogether hopeless. had | now become much emaciated-my strength almost wholly exhausted, my appetite gone and my whole l frame racked with pan Just al this stage of my disease, in addition to the ills suffered, distress ing Dysentery made it's appearance, winch complete ly prostrated me. For the last four d.ys, threw | up every thing that ute and drank. was unable 10 rest at night, and scarce able to walk my ro0m and moi without reelIng like one intoxlcated ! heard you were in this city, and immediately made application to you, and now, after having used two boxes of your Ague Pills, find myself restored to a I ueRiee OI hau uespdtFtu Oi ever hSdih ei- toying. My chills have left me, the dysenlery has disappeared under lhe magic effects, my appetite is Iesored, and returning strength and animation | to thrill my every nerve. To you owe everlasting gratitude and shall ever while live hail your ines timable Pills as my deliverer from wasting disease and certain death. THOS. FLEMING.

 We, the undersigned, are personally acquainted with Mr. Flemming, and fully e,ruborale the state- | ment above made. WILLIAM BIRD, | ABRAM GREER.

 Certificate af Rep Lsoy Massengale, Methodist Preach

 CT, Norubee County, Miss. May 9th, l843.

 This is to certify that afflicted with Ihe Sy- nocIal Fever, fever of highly infammatory ctarac- ter, which had fallen upon my bowels and produced a soreness and swelling. that could not bear the least pressure without excruciating pain. took oil and pills with small portion of calomel for several days and found no relief but grew worse daily; then for Dr. Constantine believing h,m to be the safest practitioner in the country, and he gave his Ague Pills, with some other medicine, winch gave me

 immediate relief My liule son has been afflicted with the sick headache all his life, took only small box of these pills and is measurably relieved, if entirely. therefore feel confident in recommending these pills to he public. LEROY MAssENeALE. To be had of I. C. DUBOSE, & CO.,, | DR REPRESENTATIVES.