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Colloque organisé du 24 juin au 28 septembre 1985 par René Lefever et Jacques Urbain, à l’instigation du professeur Ilya Prigogine, le séminaire « Système immunitaire et cancer » a réuni des chimistes, des biologistes et des médecins.Les interventions ont relevé de quatre thèmes principaux : Regulatory mechanisms in the immune system and growth control Cancer, immunity and metastasis, Cell mediated immune responses Manipulation of the anti-tumor immune responseCommunications Paola Allavena (Instituto Mario Negri, Milan, Italy), Regulation and function of tumor infiltrating leucocytes Benjamin Bonavida (UCLA, Dept. of Microbiology and Immunology, USA), The role of soluble cytotoxic factors in cell mediated cytotoxicity Denis M. Callewaert (Oakland University, Dept. of Chemistry, USA), Kinetic analysis of natural cytotoxicity Jean-Charles Cerottini (Ludwig Institute for Cancer Research, Epalinges, Suisse), The function of cytotoxic T lymphocytes Klaus Eichmann (Max Planck Institute for Immunology, Freiburg, Germany), T cell repertoire Michael Feldman (Weizmann Institute of Sciences, Rehovot, Israel), Genes and antigens of metastasis Philip Frost (The University of Texas, Houston, USA), Tumor metastasis Pierre Golstein (CNRS, Centre d'Immunologie de Marseille Luminy, France), Mechanisms of cytotoxicity Mark I. Green (Tufts University School of Medicine, Boston, USA), The T lymphocyte suppressor cascade Karl Erik Hellström (University of Washington, Oncogene Corporation, Seattle, USA), Idiotypic manipulations of the anti-tumor response Thierry Hercend (Institut Gustave Roussy, Villejuif, France), Mechanisms of tumor cell recognition by human natural killer lymphocytes Jean Hiernaux (Université Libre de Bruxelles (ULB), Sce Chimie-Physique II, Belgique), Kinetic analysis of CTL clones Johan Hoebecke (Institut Jacques Monod, Paris VI) Dieter Kabelitz (University of Ulm, Germany), Induction of EBV specific MHC restricted human toxicity T cells René Lefever (Université Libre de Bruxelles (ULB), Belgique), Dynamical properties of cancer tissue attacked by immune cytotoxic cells Julia G. Levy (University of British Columbia, Vancouver, Canada), Role of T supressor lymphocytes in the anti-tumor response Jacqueline Marvel (Université Libre de Bruxelles (ULB), Belgique) Maria-Grazia Masucci (Karolinska Institute, Stockhom, Sweden), Oncogene activation and tumor immunity Patricia Meyers (Laboratoire de Physiologie animale, Rhode St-Genèse, Belgique) Aviron N. Mitchison (University College London (UCL), Dept. of Zoology), Immunoregulatory T lymphocytes Ilya Prigogine (1917-2003) (Université Libre de Bruxelles (ULB), Instituts Internationaux de Physique Chimie, Belgique), Opening remarks Patrick A. Riley (School of Medicine, University College London (UCL)), Melanocyte destruction initiated by tyrosine analogs as an approach to melano therapy John H. Russel (Washington University School of Medicine, St Louis, USA), Mechanisms of cytolysis Moncef Slaoui (Medical School Boston, USA) Dominique Stehelin (Institut Pasteur, Laboratoire d'Oncologie moléculaire, Paris), Viral and cellular oncogenes Jacques Urbain (Laboratoire de Physiologie animale, Rhode St-Genèse, Belgique), Idiotypic networks: order from the beginning or order out of chaos? Catherine Uyttenhove (Ludwig Institute for Cancer Research, Epalinges, Suisse), Enhancement of tumor immunity Frederick E. Wheelock (Hahnemann Medical College, Philadelphie, USA), Tumor dormance