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By Ashley BuchananThe last line of a recipe for a nerve ointment within Anna Maria Luisa’s (1667 – 1743) collection of culinary, alchemical, and medicinal recipes reads: “this being a balm, and particular secret, which is made only in the S.A.R. fonderia, and not in another location, even if others say they have the same recipe.” Five of Anna Maria Luisa’s recipes—two fever waters, one ointment for nerves and another for burns, and a powder to control epilepsy—are attributed to the fonderia of the most serine royal highness, the grand duke of Tuscany. Of these five, three are printed on small sheets of paper and prominently emblazoned with the Medici crest. The printed recipe for fever water stated that this particular water was useful for reoccurring fevers, both malignant and acute. The directions praised the water’s success in moderating the heat of fevers in patients of all ages. It advised giving the water four or five times in the morning, but suggested reducing the dosage based on age.  Of all the recipes in Anna Maria Luisa’s collection, this is the only printed text with multiple copies. The fact that this recipe was printed, and three copies remain in her collection, suggest that this particular fever water was widely used and produced by the Medici palace fonderia, or pharmacy.Established by Cosimo I in the Palazzo Vecchio, the Medici Granducal fonderia was a laboratory where naturalists, alchemists, herbalists, pharmacists, and distillers experimented with recipes and techniques for medicinal therapeutics in addition to other metallurgical pursuits. Cosimo’s son, Francesco I, moved the fonderia to the Casino di San Marco, and again in 1586 when a new fonderia opened in the Uffizi. In 1643, Grand Duke Ferdinando II donated an additional room in the Uffizi dedicated to curiosities like stuffed exotic animals and even an Egyptian mummy, which also served in the production of medicines.[caption id="" align="aligncenter" width="374"] The studiolo or alchemical laboratory of Francesco I de Medici inside the Palazzo Vecchio (via wikimedia commons)[/caption]By the seventeenth century, and continuing well into the eighteenth century, the Uffizi fonderia was famous for its pharmaceutical production. The remedies produced in the Medici fonderia were gifted by the Grand Dukes and Duchesses in precious caskets to nobles and kings of Europe, the Middle East, and even the Americas. Numerous letters within the Medici archive (now available online, thanks to the Medici archive project) attest to the value of Medici medicines as diplomatic gifts. In 1630, Anna Maria Luisa’s great-grandmother, the Grand Duchess Maria Magdalena (Von Hapsburg), sent oils from the fonderia as a diplomatic gift to the Crown Prince of Spain.[1] In 1637 military captain and diplomat Piero della Rena, who at the time of writing was being held captive by the Pasha of Tripoli, wrote Grand Duke Ferdinando II and proposed a plan to negotiate his ransom.  In order to expedite his release, Rena suggested that in addition to money, Ferdinando send an amicable letter, a tent made of damask cloth, and a box of medicinal oils (una cassetta di olii di fonderia).[2] Clearly the products produced by the palace pharmacy were held in high esteem and as such possessed great value—value that could be used for the promotion of the Medici personally and politically.Anna Maria Luisa’s recipes attest to the avid pursuit of alchemical and technical “secrets” at the Medici court. Later male and female Medici family members set up their own fonderie for the production of medicinal oils and therapeutics. The courtly patronage of science not only highlighted the Medici’s splendor and command of nature, it also produced tangible products, like fever waters. As a member of the Medici family, Anna Maria Luisa had access to these recipes to add to her own collection, to gift for diplomatic relationships, or to exchange for other recipes. The inclusion of the Medici crest and attribution to the Medici palace pharmacy was a way in which Anna Maria Luisa could increase the value of her recipe collection. As I continue my research, I am interested in investigating Anna Maria Luisa’s interaction with the granducal fonderia. Like other Medici dukes and duchesses, did she set up her own fonderia or did she patronize the existing granducal fonderia? Understanding Anna Maria Luisa’s affiliation with the granducal fonderia will reveal whether she was a patient who used and circulated Medici therapies, or if she was also a patron and practitioner of medicine.[1] ASF, Mediceo del Principato 4962. (Entry 11641 in the Medici Archive Project Documentary Sources database.)[2] ASF, Mediceo del Principato 4274 folio 196. (Entry 22136 in the Medici Archive Project Documentary Sources database.)&#160;&#160;