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theOptntOn Of Drs DaunS WHO mas witnessed | the disease in India. It appears to me to de-S pend principally upon some peculiar and un. known change in the atmosphere, affecting the constitutions of all more or less, and prOdn- cing the disposition of the disease. that change being pr0duced more particularly in the blood,

 being highly carbOnaceUus and apparently

 destitute of that vital principle SO essentially

 necessary to support the cOnstitution.-TThe

 information since received, we are happy to

 state gives us reason to consider the writer of

 the above letter as somewhat erroneous in his cOnclusOns.-EditOr. Sunderland. NOv. 9.-I have just been at

 the Medical Board, and am sorry to say that

 there are several very alarming cases of chol- era among the lower classes. A person was

 taken ill at four o'clock, and died at 10 o'clock. Two medical gentlemen who have been in In-

 dia. informed me it is the Indian cholera. of 1 which have not much d"ubt from what l have seen. Some say it is not worse than we had before, but must say haS e never heard l Of such, as it keeps us all in alarm here. Cholera Morbus.-The official accounts from

 Sunderland this morning are still favorable {;

 hut we regret to find, by the letter of our Newcastle correspondent, that a case Of chol-

 era has occurred in that town. Courier.1 Ne,ocastle. Nov. GA letter from Sunder- ] land, dated Sept. 9. states that " matters have

 been considerably exaggerated; - and adds. that there have been thirty cases of cholera in

 all, of which eighteen have proved fatal. It

 is further observed, that {" the disease is on

 the decline"

 l On the ninth there were four deaths and

 seven new cases. On the nth, eleven new

 cases. besides fourteen of diarrhea, and two

 deaths. Oa the 18th. four new cases, besides

 eleven diarrhea; no deaths. On the 18th, l one new case, besides fi,e of diarrhea. Nov. lO.-At the meeting of the medical

 board this morning, there were no fresh Cases l of the cholera reported and we now think

 Some medical men sill persist in saying it was

 not, and by the report Of the visitors, it ap-

 pears that the place is more healthy than 1t has been for many years.

 Ne,O- Castle, Nov. 1O.-I am sorry to have

 to inform you that the cholera s still raging in Sunderland. Four people died yesterday,

 one of them after four hours illness, and there

 is every appearance ofits increasing, in conse-

 quence of mild weather, with southerly winds. We are, l am happy to say, entirely free from 1 it here, and hope, will remain SO.

 Nou. 1.-The report of the party sent t6

 Sunderland, was, that the district they visit

 ed was seldom or never in more healthy

 state; the reports, and also the opinions of the

 medical men on the subject of the cholera, are

 various and conflicting. think the Sunder-

 land cholera makes great deal more noise at Newcastle than it does here, and perhaps

 more at London than at Newcastle. Several cases of cholera appear to have occurred, but the opinions are different as to whether they are native or foreign. .-...~

 TURKEY.

 ConSt0ntin0pLe, Oct. 1O.-On the 5th inst

 a

 Der, and the effect of which has been most de- structiye, filled with terror the inhabitants of this country. who areaat the same time suf- fering under all kinds of evils. After an un- commonly sultry night, threatening clouds rose about six in the morning in the horizon, to the south and west, and noise between thunder and tempest, and yet not to he com pared with either, increased .very moment, and the inhabitants of the capital reused from their strife, awaited with anxious expecta- ton the issue of this threatening phenome- non. Their uncertainty was of not long du- ration Jumps of ice as large as a mans foot falling first singly, and then like thick show CT Of stones, which destroyed every thing with which they came in contact.

 The oldest persons do not remember ever to have seen such hail stones. Some were picked up half an hour afterwards, which "oI6ucu aUOSV pound. rms dreadful storm passed over Constantinople and along the Bnsphorus, over Bujukdere and Belgrade, and the fairest. nay, the only hope of this beautiful and fertile tract, the vintage just was destroyed in day. Ami. mals of all kinds, and even some persons, gre said to have been killed; an innumerable quan- tity are wounded. and the damage done to the houses is incaleulable. Besides that scarcely a window has escaped in all the country, the force of the falling masses of ice was SO great. that they broke to atoms all the tiles on the roofs, and shattered like musket- balls planks half an inch thick. Since that day the rain l has not ceased fo pour down in torrents, and from the slight way in which the houses are l built. almost wholly consisting of windows. 1 and with very hat@roofs that have nothing 1 to keep off the wet besides tiles, innumsrable 1 families are not much more comfortable than 1 ia bivouac. If, in addition to this, NC con- sider that in consequence of the burning of Pera. and the great fires in Constantinople it. self, many have no shelter whatever. and re- f collect besides the. plague which continues to spread, and theseases of cholera which still oc- cur, both together indeed make the whole most gloomy picture.

 Milledgeuille. Dec. 2S.-GeorgiG Legisla- t@re.-The House this morning passed the bill from the Senate, commonly known by the name of tue Gold Mine Bill, without 84. nays sl. You have already received a copy of the bill. It pro-