Fatty acid oxidation inhibitors
# Fatty acid oxidation inhibitors

Fatty acid oxidation inhibitors are a new potent class of drugs used in treatment of stable angina pectoris and an addition in treatment of chronic heart failure.

## Drugs

* CPT-I inhibitors: Etomoxir, Oxfenicine, Perhexiline CPT-I (carnitine palmitoyl transferase) converts fatty acyl-CoA to fatty acyl-carnitine.
* Carnitine biosynthesis inhibitor: Mildronate
* 3-KAT inhibitors: Trimetazidine 3-KAT (3-ketoacyl-coenzyme A thiolase) inhibitors directly inhibits fatty acid beta-oxidation.
* pFOX directly inhibits fatty acid beta-oxidation.
